(13 nodes) Positive regulation of integrin-mediated signaling pathway, and Regulation of cytoskeletal remodeling and cell spreading by IPP complex components network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107572539	LIM and senescent cell antigen-like-containing domain protein 1. (351 aa)
	Parvg	Gamma-parvin isoform X1. (305 aa)
	LOC107571343	Beta-parvin-like. (365 aa)
	rsu1	Ras suppressor protein 1 isoform X1. (277 aa)
	ENSSGRP00000071641	Parvin, alpha a. (370 aa)
	Ilk	Integrin-linked protein kinase. (434 aa)
	ENSSGRP00000087559	Integrin-linked kinase. (442 aa)
	ENSSGRP00000088665	annotation not available (60 aa)
	ENSSGRP00000088671	LIM and senescent cell antigen-like-containing domain protein 1. (340 aa)
	ENSSGRP00000088710	Ras suppressor protein 1. (257 aa)
	ENSSGRP00000088711	annotation not available (45 aa)
	LOC107551808	LIM and senescent cell antigen-like-containing domain protein 1 isoform X1. (363 aa)
	ENSSGRP00000099500	Parvin, gamma. (265 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000071641	ENSSGRP00000087559	ENSSGRP00000071641	ENSSGRP00000087559	Parvin, alpha a.	Integrin-linked kinase.	0.973
ENSSGRP00000071641	ENSSGRP00000088665	ENSSGRP00000071641	ENSSGRP00000088665	Parvin, alpha a.	annotation not available	0.861
ENSSGRP00000071641	ENSSGRP00000088671	ENSSGRP00000071641	ENSSGRP00000088671	Parvin, alpha a.	LIM and senescent cell antigen-like-containing domain protein 1.	0.861
ENSSGRP00000071641	ENSSGRP00000088710	ENSSGRP00000071641	ENSSGRP00000088710	Parvin, alpha a.	Ras suppressor protein 1.	0.703
ENSSGRP00000071641	ENSSGRP00000088711	ENSSGRP00000071641	ENSSGRP00000088711	Parvin, alpha a.	annotation not available	0.703
ENSSGRP00000071641	Ilk	ENSSGRP00000071641	ENSSGRP00000081918	Parvin, alpha a.	Integrin-linked protein kinase.	0.973
ENSSGRP00000071641	LOC107551808	ENSSGRP00000071641	ENSSGRP00000096913	Parvin, alpha a.	LIM and senescent cell antigen-like-containing domain protein 1 isoform X1.	0.861
ENSSGRP00000071641	LOC107572539	ENSSGRP00000071641	ENSSGRP00000009035	Parvin, alpha a.	LIM and senescent cell antigen-like-containing domain protein 1.	0.861
ENSSGRP00000071641	rsu1	ENSSGRP00000071641	ENSSGRP00000030889	Parvin, alpha a.	Ras suppressor protein 1 isoform X1.	0.703
ENSSGRP00000087559	ENSSGRP00000071641	ENSSGRP00000087559	ENSSGRP00000071641	Integrin-linked kinase.	Parvin, alpha a.	0.973
ENSSGRP00000087559	ENSSGRP00000088665	ENSSGRP00000087559	ENSSGRP00000088665	Integrin-linked kinase.	annotation not available	0.977
ENSSGRP00000087559	ENSSGRP00000088671	ENSSGRP00000087559	ENSSGRP00000088671	Integrin-linked kinase.	LIM and senescent cell antigen-like-containing domain protein 1.	0.977
ENSSGRP00000087559	ENSSGRP00000088710	ENSSGRP00000087559	ENSSGRP00000088710	Integrin-linked kinase.	Ras suppressor protein 1.	0.931
ENSSGRP00000087559	ENSSGRP00000088711	ENSSGRP00000087559	ENSSGRP00000088711	Integrin-linked kinase.	annotation not available	0.931
ENSSGRP00000087559	ENSSGRP00000099500	ENSSGRP00000087559	ENSSGRP00000099500	Integrin-linked kinase.	Parvin, gamma.	0.959
ENSSGRP00000087559	LOC107551808	ENSSGRP00000087559	ENSSGRP00000096913	Integrin-linked kinase.	LIM and senescent cell antigen-like-containing domain protein 1 isoform X1.	0.977
ENSSGRP00000087559	LOC107571343	ENSSGRP00000087559	ENSSGRP00000030741	Integrin-linked kinase.	Beta-parvin-like.	0.971
ENSSGRP00000087559	LOC107572539	ENSSGRP00000087559	ENSSGRP00000009035	Integrin-linked kinase.	LIM and senescent cell antigen-like-containing domain protein 1.	0.977
ENSSGRP00000087559	Parvg	ENSSGRP00000087559	ENSSGRP00000030740	Integrin-linked kinase.	Gamma-parvin isoform X1.	0.959
ENSSGRP00000087559	rsu1	ENSSGRP00000087559	ENSSGRP00000030889	Integrin-linked kinase.	Ras suppressor protein 1 isoform X1.	0.931