(6 nodes) Mixed, incl. Intronic transcription regulatory region sequence-specific DNA binding, and Regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pak2	Serine/threonine-protein kinase PAK 2. (471 aa)
	LOC107570753	Mitogen-activated protein kinase kinase kinase 3-like isoform X1. (620 aa)
	LOC107591272	Mitogen-activated protein kinase kinase kinase 3-like. (604 aa)
	ENSSGRP00000061753	SET and MYND domain containing 3. (329 aa)
	LOC107557297	Serine/threonine-protein kinase PAK 2-like. (518 aa)
	ENSSGRP00000082594	Mitogen-activated protein kinase kinase kinase 3-like. (621 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000061753	ENSSGRP00000082594	ENSSGRP00000061753	ENSSGRP00000082594	SET and MYND domain containing 3.	Mitogen-activated protein kinase kinase kinase 3-like.	0.689
ENSSGRP00000061753	LOC107570753	ENSSGRP00000061753	ENSSGRP00000025402	SET and MYND domain containing 3.	Mitogen-activated protein kinase kinase kinase 3-like isoform X1.	0.689
ENSSGRP00000061753	LOC107591272	ENSSGRP00000061753	ENSSGRP00000057294	SET and MYND domain containing 3.	Mitogen-activated protein kinase kinase kinase 3-like.	0.689
ENSSGRP00000082594	ENSSGRP00000061753	ENSSGRP00000082594	ENSSGRP00000061753	Mitogen-activated protein kinase kinase kinase 3-like.	SET and MYND domain containing 3.	0.689
ENSSGRP00000082594	LOC107557297	ENSSGRP00000082594	ENSSGRP00000070239	Mitogen-activated protein kinase kinase kinase 3-like.	Serine/threonine-protein kinase PAK 2-like.	0.941
ENSSGRP00000082594	Pak2	ENSSGRP00000082594	ENSSGRP00000021375	Mitogen-activated protein kinase kinase kinase 3-like.	Serine/threonine-protein kinase PAK 2.	0.936
LOC107557297	ENSSGRP00000082594	ENSSGRP00000070239	ENSSGRP00000082594	Serine/threonine-protein kinase PAK 2-like.	Mitogen-activated protein kinase kinase kinase 3-like.	0.941
LOC107557297	LOC107570753	ENSSGRP00000070239	ENSSGRP00000025402	Serine/threonine-protein kinase PAK 2-like.	Mitogen-activated protein kinase kinase kinase 3-like isoform X1.	0.940
LOC107557297	LOC107591272	ENSSGRP00000070239	ENSSGRP00000057294	Serine/threonine-protein kinase PAK 2-like.	Mitogen-activated protein kinase kinase kinase 3-like.	0.941
LOC107570753	ENSSGRP00000061753	ENSSGRP00000025402	ENSSGRP00000061753	Mitogen-activated protein kinase kinase kinase 3-like isoform X1.	SET and MYND domain containing 3.	0.689
LOC107570753	LOC107557297	ENSSGRP00000025402	ENSSGRP00000070239	Mitogen-activated protein kinase kinase kinase 3-like isoform X1.	Serine/threonine-protein kinase PAK 2-like.	0.940
LOC107570753	Pak2	ENSSGRP00000025402	ENSSGRP00000021375	Mitogen-activated protein kinase kinase kinase 3-like isoform X1.	Serine/threonine-protein kinase PAK 2.	0.936
LOC107591272	ENSSGRP00000061753	ENSSGRP00000057294	ENSSGRP00000061753	Mitogen-activated protein kinase kinase kinase 3-like.	SET and MYND domain containing 3.	0.689
LOC107591272	LOC107557297	ENSSGRP00000057294	ENSSGRP00000070239	Mitogen-activated protein kinase kinase kinase 3-like.	Serine/threonine-protein kinase PAK 2-like.	0.941
LOC107591272	Pak2	ENSSGRP00000057294	ENSSGRP00000021375	Mitogen-activated protein kinase kinase kinase 3-like.	Serine/threonine-protein kinase PAK 2.	0.936
Pak2	ENSSGRP00000082594	ENSSGRP00000021375	ENSSGRP00000082594	Serine/threonine-protein kinase PAK 2.	Mitogen-activated protein kinase kinase kinase 3-like.	0.936
Pak2	LOC107570753	ENSSGRP00000021375	ENSSGRP00000025402	Serine/threonine-protein kinase PAK 2.	Mitogen-activated protein kinase kinase kinase 3-like isoform X1.	0.936
Pak2	LOC107591272	ENSSGRP00000021375	ENSSGRP00000057294	Serine/threonine-protein kinase PAK 2.	Mitogen-activated protein kinase kinase kinase 3-like.	0.936