(20 nodes) Mixed, incl. Rabaptin, and Kit signaling pathway network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB5A	RAB5A, member RAS oncogene family. (61 aa)
	ENSSGRP00000009081	annotation not available (71 aa)
	LOC107590564	Rab GTPase-binding effector protein 2-like. (457 aa)
	LOC107598172	Ras-related protein Rab-5B-like. (214 aa)
	LOC107597410	Rabankyrin-5-like. (1169 aa)
	LOC107577469	Rab5 GDP/GTP exchange factor-like isoform X1. (551 aa)
	ENSSGRP00000034707	RAB guanine nucleotide exchange factor (GEF) 1, like. (455 aa)
	ENSSGRP00000040142	RAB5A, member RAS oncogene family, b. (121 aa)
	LOC107550582	GTPase-activating protein and VPS9 domain-containing protein 1-like isoform X1. (1478 aa)
	ENSSGRP00000055376	RAB guanine nucleotide exchange factor (GEF) 1. (390 aa)
	LOC107553935	Early endosome antigen 1-like. (1369 aa)
	Rabep1	LOW QUALITY PROTEIN: rab GTPase-binding effector protein 1. (835 aa)
	ENSSGRP00000071444	annotation not available (85 aa)
	ENSSGRP00000073287	GTPase-activating protein and VPS9 domain-containing protein 1-like. (1386 aa)
	ENSSGRP00000076312	Early endosome antigen 1-like isoform X1. (1390 aa)
	ENSSGRP00000080884	Rab GTPase-binding effector protein 1-like. (55 aa)
	ENSSGRP00000092711	Rab GTPase-binding effector protein 2-like. (472 aa)
	RAB20-2	Ras-related protein Rab-20-like. (246 aa)
	LOC107592111	Ras-related protein Rab-5A-like. (216 aa)
	LOC107551955	Ras-related protein Rab-5B-like. (214 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000009081	ENSSGRP00000034707	ENSSGRP00000009081	ENSSGRP00000034707	annotation not available	RAB guanine nucleotide exchange factor (GEF) 1, like.	0.968
ENSSGRP00000009081	ENSSGRP00000055376	ENSSGRP00000009081	ENSSGRP00000055376	annotation not available	RAB guanine nucleotide exchange factor (GEF) 1.	0.968
ENSSGRP00000009081	ENSSGRP00000071444	ENSSGRP00000009081	ENSSGRP00000071444	annotation not available	annotation not available	0.968
ENSSGRP00000009081	ENSSGRP00000073287	ENSSGRP00000009081	ENSSGRP00000073287	annotation not available	GTPase-activating protein and VPS9 domain-containing protein 1-like.	0.667
ENSSGRP00000009081	ENSSGRP00000080884	ENSSGRP00000009081	ENSSGRP00000080884	annotation not available	Rab GTPase-binding effector protein 1-like.	0.548
ENSSGRP00000009081	ENSSGRP00000092711	ENSSGRP00000009081	ENSSGRP00000092711	annotation not available	Rab GTPase-binding effector protein 2-like.	0.548
ENSSGRP00000009081	LOC107550582	ENSSGRP00000009081	ENSSGRP00000041817	annotation not available	GTPase-activating protein and VPS9 domain-containing protein 1-like isoform X1.	0.667
ENSSGRP00000009081	LOC107577469	ENSSGRP00000009081	ENSSGRP00000028638	annotation not available	Rab5 GDP/GTP exchange factor-like isoform X1.	0.968
ENSSGRP00000009081	LOC107590564	ENSSGRP00000009081	ENSSGRP00000010812	annotation not available	Rab GTPase-binding effector protein 2-like.	0.548
ENSSGRP00000009081	LOC107597410	ENSSGRP00000009081	ENSSGRP00000025781	annotation not available	Rabankyrin-5-like.	0.746
ENSSGRP00000009081	Rabep1	ENSSGRP00000009081	ENSSGRP00000059729	annotation not available	LOW QUALITY PROTEIN: rab GTPase-binding effector protein 1.	0.548
ENSSGRP00000034707	ENSSGRP00000009081	ENSSGRP00000034707	ENSSGRP00000009081	RAB guanine nucleotide exchange factor (GEF) 1, like.	annotation not available	0.968
ENSSGRP00000034707	ENSSGRP00000040142	ENSSGRP00000034707	ENSSGRP00000040142	RAB guanine nucleotide exchange factor (GEF) 1, like.	RAB5A, member RAS oncogene family, b.	0.968
ENSSGRP00000034707	ENSSGRP00000055376	ENSSGRP00000034707	ENSSGRP00000055376	RAB guanine nucleotide exchange factor (GEF) 1, like.	RAB guanine nucleotide exchange factor (GEF) 1.	0.688
ENSSGRP00000034707	ENSSGRP00000071444	ENSSGRP00000034707	ENSSGRP00000071444	RAB guanine nucleotide exchange factor (GEF) 1, like.	annotation not available	0.681
ENSSGRP00000034707	ENSSGRP00000073287	ENSSGRP00000034707	ENSSGRP00000073287	RAB guanine nucleotide exchange factor (GEF) 1, like.	GTPase-activating protein and VPS9 domain-containing protein 1-like.	0.615
ENSSGRP00000034707	ENSSGRP00000076312	ENSSGRP00000034707	ENSSGRP00000076312	RAB guanine nucleotide exchange factor (GEF) 1, like.	Early endosome antigen 1-like isoform X1.	0.736
ENSSGRP00000034707	ENSSGRP00000080884	ENSSGRP00000034707	ENSSGRP00000080884	RAB guanine nucleotide exchange factor (GEF) 1, like.	Rab GTPase-binding effector protein 1-like.	0.999
ENSSGRP00000034707	ENSSGRP00000092711	ENSSGRP00000034707	ENSSGRP00000092711	RAB guanine nucleotide exchange factor (GEF) 1, like.	Rab GTPase-binding effector protein 2-like.	0.999
ENSSGRP00000034707	LOC107550582	ENSSGRP00000034707	ENSSGRP00000041817	RAB guanine nucleotide exchange factor (GEF) 1, like.	GTPase-activating protein and VPS9 domain-containing protein 1-like isoform X1.	0.615