(11 nodes) Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000009273	Stimulator of interferon genes protein-like. (249 aa)
	LOC107582288	TNF receptor-associated factor 3-like isoform X1. (575 aa)
	ENSSGRP00000041514	Stimulator of interferon response cGAMP interactor 1. (387 aa)
	LOC107590150	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like isoform X1. (731 aa)
	LOC107561568	TRAF family member-associated NF-kappa-B activator-like isoform X1. (349 aa)
	LOC107598585	Interferon regulatory factor 3-like. (459 aa)
	LOC107590913	TNF receptor-associated factor 3-like. (573 aa)
	LOC107557350	Interferon regulatory factor 3-like isoform X1. (455 aa)
	LOC107555619	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like. (722 aa)
	LOC107563834	TRAF family member-associated NF-kappa-B activator-like isoform X1. (349 aa)
	LOC107561249	Serine/threonine-protein kinase TBK1-like isoform X1. (741 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000009273	LOC107555619	ENSSGRP00000009273	ENSSGRP00000092151	Stimulator of interferon genes protein-like.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	0.995
ENSSGRP00000009273	LOC107557350	ENSSGRP00000009273	ENSSGRP00000090613	Stimulator of interferon genes protein-like.	Interferon regulatory factor 3-like isoform X1.	0.974
ENSSGRP00000009273	LOC107561249	ENSSGRP00000009273	ENSSGRP00000102302	Stimulator of interferon genes protein-like.	Serine/threonine-protein kinase TBK1-like isoform X1.	0.995
ENSSGRP00000009273	LOC107590150	ENSSGRP00000009273	ENSSGRP00000045554	Stimulator of interferon genes protein-like.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like isoform X1.	0.995
ENSSGRP00000009273	LOC107598585	ENSSGRP00000009273	ENSSGRP00000064815	Stimulator of interferon genes protein-like.	Interferon regulatory factor 3-like.	0.974
ENSSGRP00000041514	LOC107555619	ENSSGRP00000041514	ENSSGRP00000092151	Stimulator of interferon response cGAMP interactor 1.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	0.953
ENSSGRP00000041514	LOC107557350	ENSSGRP00000041514	ENSSGRP00000090613	Stimulator of interferon response cGAMP interactor 1.	Interferon regulatory factor 3-like isoform X1.	0.974
ENSSGRP00000041514	LOC107561249	ENSSGRP00000041514	ENSSGRP00000102302	Stimulator of interferon response cGAMP interactor 1.	Serine/threonine-protein kinase TBK1-like isoform X1.	0.953
ENSSGRP00000041514	LOC107590150	ENSSGRP00000041514	ENSSGRP00000045554	Stimulator of interferon response cGAMP interactor 1.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like isoform X1.	0.953
ENSSGRP00000041514	LOC107598585	ENSSGRP00000041514	ENSSGRP00000064815	Stimulator of interferon response cGAMP interactor 1.	Interferon regulatory factor 3-like.	0.974
LOC107555619	ENSSGRP00000009273	ENSSGRP00000092151	ENSSGRP00000009273	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	Stimulator of interferon genes protein-like.	0.995
LOC107555619	ENSSGRP00000041514	ENSSGRP00000092151	ENSSGRP00000041514	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	Stimulator of interferon response cGAMP interactor 1.	0.953
LOC107555619	LOC107557350	ENSSGRP00000092151	ENSSGRP00000090613	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	Interferon regulatory factor 3-like isoform X1.	0.992
LOC107555619	LOC107561249	ENSSGRP00000092151	ENSSGRP00000102302	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	Serine/threonine-protein kinase TBK1-like isoform X1.	0.900
LOC107555619	LOC107561568	ENSSGRP00000092151	ENSSGRP00000054633	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	TRAF family member-associated NF-kappa-B activator-like isoform X1.	0.995
LOC107555619	LOC107563834	ENSSGRP00000092151	ENSSGRP00000101479	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	TRAF family member-associated NF-kappa-B activator-like isoform X1.	0.995
LOC107555619	LOC107582288	ENSSGRP00000092151	ENSSGRP00000028389	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	TNF receptor-associated factor 3-like isoform X1.	0.982
LOC107555619	LOC107590150	ENSSGRP00000092151	ENSSGRP00000045554	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like isoform X1.	0.900
LOC107555619	LOC107590913	ENSSGRP00000092151	ENSSGRP00000076450	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	TNF receptor-associated factor 3-like.	0.982
LOC107555619	LOC107598585	ENSSGRP00000092151	ENSSGRP00000064815	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	Interferon regulatory factor 3-like.	0.992