(25 nodes) Death-inducing signaling complex, and Amyloid fibril formation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107554068	Tumor necrosis factor receptor superfamily member 6-like isoform X1. (298 aa)
	LOC107583548	Tumor necrosis factor receptor superfamily member 6-like. (306 aa)
	ENSSGRP00000005841	CASP8 and FADD-like apoptosis regulator b. (187 aa)
	ENSSGRP00000006151	Caspase-8-like isoform X1. (152 aa)
	ENSSGRP00000012313	annotation not available (215 aa)
	ENSSGRP00000018945	annotation not available (555 aa)
	ENSSGRP00000029534	Caspase-8-like. (202 aa)
	ENSSGRP00000029537	annotation not available (218 aa)
	ENSSGRP00000029960	Receptor-interacting serine-threonine kinase 3. (364 aa)
	ENSSGRP00000031237	Caspase-8-like. (477 aa)
	LOC107555418	Caspase-8-like. (324 aa)
	ENSSGRP00000031485	Caspase-8-like. (140 aa)
	ENSSGRP00000034839	Caspase 10, apoptosis-related cysteine peptidase. (471 aa)
	ENSSGRP00000034880	CASP8 and FADD-like apoptosis regulator. (475 aa)
	ENSSGRP00000051562	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (574 aa)
	ENSSGRP00000059563	Receptor-interacting serine-threonine kinase 3. (332 aa)
	ENSSGRP00000069856	Fas ligand (TNF superfamily, member 6). (292 aa)
	LOC107559437	FAS-associated death domain protein-like. (192 aa)
	ENSSGRP00000086633	CASP8 and FADD-like apoptosis regulator. (221 aa)
	ENSSGRP00000087301	annotation not available (286 aa)
	ENSSGRP00000087331	Caspase-8-like. (228 aa)
	LOC107549841	Death domain-associated protein 6-like isoform X1. (698 aa)
	Mlkl	Mixed lineage kinase domain-like protein isoform X1. (468 aa)
	LOC107563912	Tumor necrosis factor receptor superfamily member 6-like. (435 aa)
	LOC107570294	CASP8 and FADD-like apoptosis regulator. (494 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000005841	ENSSGRP00000006151	ENSSGRP00000005841	ENSSGRP00000006151	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like isoform X1.	0.769
ENSSGRP00000005841	ENSSGRP00000018945	ENSSGRP00000005841	ENSSGRP00000018945	CASP8 and FADD-like apoptosis regulator b.	annotation not available	0.745
ENSSGRP00000005841	ENSSGRP00000029534	ENSSGRP00000005841	ENSSGRP00000029534	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000029537	ENSSGRP00000005841	ENSSGRP00000029537	CASP8 and FADD-like apoptosis regulator b.	annotation not available	0.769
ENSSGRP00000005841	ENSSGRP00000029960	ENSSGRP00000005841	ENSSGRP00000029960	CASP8 and FADD-like apoptosis regulator b.	Receptor-interacting serine-threonine kinase 3.	0.602
ENSSGRP00000005841	ENSSGRP00000031237	ENSSGRP00000005841	ENSSGRP00000031237	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000031485	ENSSGRP00000005841	ENSSGRP00000031485	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000034839	ENSSGRP00000005841	ENSSGRP00000034839	CASP8 and FADD-like apoptosis regulator b.	Caspase 10, apoptosis-related cysteine peptidase.	0.769
ENSSGRP00000005841	ENSSGRP00000051562	ENSSGRP00000005841	ENSSGRP00000051562	CASP8 and FADD-like apoptosis regulator b.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.745
ENSSGRP00000005841	ENSSGRP00000059563	ENSSGRP00000005841	ENSSGRP00000059563	CASP8 and FADD-like apoptosis regulator b.	Receptor-interacting serine-threonine kinase 3.	0.602
ENSSGRP00000005841	ENSSGRP00000069856	ENSSGRP00000005841	ENSSGRP00000069856	CASP8 and FADD-like apoptosis regulator b.	Fas ligand (TNF superfamily, member 6).	0.572
ENSSGRP00000005841	ENSSGRP00000087301	ENSSGRP00000005841	ENSSGRP00000087301	CASP8 and FADD-like apoptosis regulator b.	annotation not available	0.769
ENSSGRP00000005841	ENSSGRP00000087331	ENSSGRP00000005841	ENSSGRP00000087331	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	LOC107554068	ENSSGRP00000005841	ENSSGRP00000001837	CASP8 and FADD-like apoptosis regulator b.	Tumor necrosis factor receptor superfamily member 6-like isoform X1.	0.767
ENSSGRP00000005841	LOC107555418	ENSSGRP00000005841	ENSSGRP00000031239	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	LOC107559437	ENSSGRP00000005841	ENSSGRP00000074211	CASP8 and FADD-like apoptosis regulator b.	FAS-associated death domain protein-like.	0.935
ENSSGRP00000005841	LOC107563912	ENSSGRP00000005841	ENSSGRP00000104634	CASP8 and FADD-like apoptosis regulator b.	Tumor necrosis factor receptor superfamily member 6-like.	0.745
ENSSGRP00000005841	LOC107583548	ENSSGRP00000005841	ENSSGRP00000005561	CASP8 and FADD-like apoptosis regulator b.	Tumor necrosis factor receptor superfamily member 6-like.	0.767
ENSSGRP00000005841	Mlkl	ENSSGRP00000005841	ENSSGRP00000093378	CASP8 and FADD-like apoptosis regulator b.	Mixed lineage kinase domain-like protein isoform X1.	0.484
ENSSGRP00000006151	ENSSGRP00000005841	ENSSGRP00000006151	ENSSGRP00000005841	Caspase-8-like isoform X1.	CASP8 and FADD-like apoptosis regulator b.	0.769