(7 nodes) Pyrin domain binding, and Inflammasome complex network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000002159	annotation not available (384 aa)
	ENSSGRP00000006976	NACHT, LRR and PYD domains-containing protein 12-like isoform X1. (654 aa)
	ENSSGRP00000011951	PYD and CARD domain containing. (198 aa)
	ENSSGRP00000018200	Caspase-1-A-like. (386 aa)
	ENSSGRP00000028646	Si:dkey-238o14.3. (913 aa)
	LOC107593958	Uncharacterized protein LOC107593958 isoform X1. (226 aa)
	ENSSGRP00000034418	PYD and CARD domain containing. (201 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000002159	ENSSGRP00000011951	ENSSGRP00000002159	ENSSGRP00000011951	annotation not available	PYD and CARD domain containing.	0.803
ENSSGRP00000002159	ENSSGRP00000034418	ENSSGRP00000002159	ENSSGRP00000034418	annotation not available	PYD and CARD domain containing.	0.803
ENSSGRP00000006976	ENSSGRP00000011951	ENSSGRP00000006976	ENSSGRP00000011951	NACHT, LRR and PYD domains-containing protein 12-like isoform X1.	PYD and CARD domain containing.	0.910
ENSSGRP00000006976	ENSSGRP00000034418	ENSSGRP00000006976	ENSSGRP00000034418	NACHT, LRR and PYD domains-containing protein 12-like isoform X1.	PYD and CARD domain containing.	0.910
ENSSGRP00000006976	LOC107593958	ENSSGRP00000006976	ENSSGRP00000032493	NACHT, LRR and PYD domains-containing protein 12-like isoform X1.	Uncharacterized protein LOC107593958 isoform X1.	0.523
ENSSGRP00000011951	ENSSGRP00000002159	ENSSGRP00000011951	ENSSGRP00000002159	PYD and CARD domain containing.	annotation not available	0.803
ENSSGRP00000011951	ENSSGRP00000006976	ENSSGRP00000011951	ENSSGRP00000006976	PYD and CARD domain containing.	NACHT, LRR and PYD domains-containing protein 12-like isoform X1.	0.910
ENSSGRP00000011951	ENSSGRP00000018200	ENSSGRP00000011951	ENSSGRP00000018200	PYD and CARD domain containing.	Caspase-1-A-like.	0.803
ENSSGRP00000011951	ENSSGRP00000028646	ENSSGRP00000011951	ENSSGRP00000028646	PYD and CARD domain containing.	Si:dkey-238o14.3.	0.910
ENSSGRP00000011951	LOC107593958	ENSSGRP00000011951	ENSSGRP00000032493	PYD and CARD domain containing.	Uncharacterized protein LOC107593958 isoform X1.	0.640
ENSSGRP00000018200	ENSSGRP00000011951	ENSSGRP00000018200	ENSSGRP00000011951	Caspase-1-A-like.	PYD and CARD domain containing.	0.803
ENSSGRP00000018200	ENSSGRP00000034418	ENSSGRP00000018200	ENSSGRP00000034418	Caspase-1-A-like.	PYD and CARD domain containing.	0.803
ENSSGRP00000028646	ENSSGRP00000011951	ENSSGRP00000028646	ENSSGRP00000011951	Si:dkey-238o14.3.	PYD and CARD domain containing.	0.910
ENSSGRP00000028646	ENSSGRP00000034418	ENSSGRP00000028646	ENSSGRP00000034418	Si:dkey-238o14.3.	PYD and CARD domain containing.	0.910
ENSSGRP00000028646	LOC107593958	ENSSGRP00000028646	ENSSGRP00000032493	Si:dkey-238o14.3.	Uncharacterized protein LOC107593958 isoform X1.	0.523
ENSSGRP00000034418	ENSSGRP00000002159	ENSSGRP00000034418	ENSSGRP00000002159	PYD and CARD domain containing.	annotation not available	0.803
ENSSGRP00000034418	ENSSGRP00000006976	ENSSGRP00000034418	ENSSGRP00000006976	PYD and CARD domain containing.	NACHT, LRR and PYD domains-containing protein 12-like isoform X1.	0.910
ENSSGRP00000034418	ENSSGRP00000018200	ENSSGRP00000034418	ENSSGRP00000018200	PYD and CARD domain containing.	Caspase-1-A-like.	0.803
ENSSGRP00000034418	ENSSGRP00000028646	ENSSGRP00000034418	ENSSGRP00000028646	PYD and CARD domain containing.	Si:dkey-238o14.3.	0.910
ENSSGRP00000034418	LOC107593958	ENSSGRP00000034418	ENSSGRP00000032493	PYD and CARD domain containing.	Uncharacterized protein LOC107593958 isoform X1.	0.640