(20 nodes) Mixed, incl. JUN kinase kinase activity, and JUN kinase activity network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000008754	Mitogen-activated protein kinase kinase kinase 10-like. (769 aa)
	ENSSGRP00000022438	Mitogen-activated protein kinase kinase 4a. (367 aa)
	ENSSGRP00000022808	Dual specificity mitogen-activated protein kinase kinase 4-like. (254 aa)
	LOC107590058	Mitogen-activated protein kinase 9-like. (449 aa)
	LOC107571265	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase). (433 aa)
	Map3k1	Mitogen-activated protein kinase kinase kinase 1. (1365 aa)
	ENSSGRP00000043585	Mitogen-activated protein kinase kinase kinase 1-like. (1356 aa)
	LOC107601595	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1. (384 aa)
	ENSSGRP00000057787	Mitogen-activated protein kinase 8 interacting protein 1. (486 aa)
	ENSSGRP00000059502	Mitogen-activated protein kinase kinase 7. (288 aa)
	LOC107599899	C-Jun-amino-terminal kinase-interacting protein 2-like isoform X1. (1243 aa)
	mapk8ip3	C-Jun-amino-terminal kinase-interacting protein 3 isoform X1. (1306 aa)
	LOC107588610	Mitogen-activated protein kinase 8B. (458 aa)
	ENSSGRP00000084055	Mitogen-activated protein kinase kinase kinase 11-like. (742 aa)
	Mapk8ip1	Mitogen-activated protein kinase 8 interacting protein 1. (576 aa)
	Map2k7	Dual specificity mitogen-activated protein kinase kinase 7. (390 aa)
	LOC107548633	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase). (448 aa)
	ENSSGRP00000091645	Mitogen-activated protein kinase 8 interacting protein 3. (1199 aa)
	ENSSGRP00000102420	Mitogen-activated protein kinase 10. (531 aa)
	LOC107556463	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1. (415 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000008754	ENSSGRP00000022438	ENSSGRP00000008754	ENSSGRP00000022438	Mitogen-activated protein kinase kinase kinase 10-like.	Mitogen-activated protein kinase kinase 4a.	0.498
ENSSGRP00000008754	ENSSGRP00000022808	ENSSGRP00000008754	ENSSGRP00000022808	Mitogen-activated protein kinase kinase kinase 10-like.	Dual specificity mitogen-activated protein kinase kinase 4-like.	0.498
ENSSGRP00000008754	ENSSGRP00000057787	ENSSGRP00000008754	ENSSGRP00000057787	Mitogen-activated protein kinase kinase kinase 10-like.	Mitogen-activated protein kinase 8 interacting protein 1.	0.915
ENSSGRP00000008754	ENSSGRP00000059502	ENSSGRP00000008754	ENSSGRP00000059502	Mitogen-activated protein kinase kinase kinase 10-like.	Mitogen-activated protein kinase kinase 7.	0.545
ENSSGRP00000008754	ENSSGRP00000084055	ENSSGRP00000008754	ENSSGRP00000084055	Mitogen-activated protein kinase kinase kinase 10-like.	Mitogen-activated protein kinase kinase kinase 11-like.	0.901
ENSSGRP00000008754	ENSSGRP00000091645	ENSSGRP00000008754	ENSSGRP00000091645	Mitogen-activated protein kinase kinase kinase 10-like.	Mitogen-activated protein kinase 8 interacting protein 3.	0.913
ENSSGRP00000008754	LOC107556463	ENSSGRP00000008754	ENSSGRP00000107492	Mitogen-activated protein kinase kinase kinase 10-like.	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1.	0.498
ENSSGRP00000008754	LOC107599899	ENSSGRP00000008754	ENSSGRP00000062308	Mitogen-activated protein kinase kinase kinase 10-like.	C-Jun-amino-terminal kinase-interacting protein 2-like isoform X1.	0.915
ENSSGRP00000008754	LOC107601595	ENSSGRP00000008754	ENSSGRP00000051398	Mitogen-activated protein kinase kinase kinase 10-like.	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1.	0.498
ENSSGRP00000008754	Map2k7	ENSSGRP00000008754	ENSSGRP00000088976	Mitogen-activated protein kinase kinase kinase 10-like.	Dual specificity mitogen-activated protein kinase kinase 7.	0.952
ENSSGRP00000008754	Mapk8ip1	ENSSGRP00000008754	ENSSGRP00000085731	Mitogen-activated protein kinase kinase kinase 10-like.	Mitogen-activated protein kinase 8 interacting protein 1.	0.915
ENSSGRP00000008754	mapk8ip3	ENSSGRP00000008754	ENSSGRP00000064819	Mitogen-activated protein kinase kinase kinase 10-like.	C-Jun-amino-terminal kinase-interacting protein 3 isoform X1.	0.913
ENSSGRP00000022438	ENSSGRP00000008754	ENSSGRP00000022438	ENSSGRP00000008754	Mitogen-activated protein kinase kinase 4a.	Mitogen-activated protein kinase kinase kinase 10-like.	0.498
ENSSGRP00000022438	ENSSGRP00000043585	ENSSGRP00000022438	ENSSGRP00000043585	Mitogen-activated protein kinase kinase 4a.	Mitogen-activated protein kinase kinase kinase 1-like.	0.919
ENSSGRP00000022438	ENSSGRP00000059502	ENSSGRP00000022438	ENSSGRP00000059502	Mitogen-activated protein kinase kinase 4a.	Mitogen-activated protein kinase kinase 7.	0.756
ENSSGRP00000022438	ENSSGRP00000084055	ENSSGRP00000022438	ENSSGRP00000084055	Mitogen-activated protein kinase kinase 4a.	Mitogen-activated protein kinase kinase kinase 11-like.	0.498
ENSSGRP00000022438	ENSSGRP00000102420	ENSSGRP00000022438	ENSSGRP00000102420	Mitogen-activated protein kinase kinase 4a.	Mitogen-activated protein kinase 10.	0.900
ENSSGRP00000022438	LOC107548633	ENSSGRP00000022438	ENSSGRP00000089609	Mitogen-activated protein kinase kinase 4a.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.909
ENSSGRP00000022438	LOC107571265	ENSSGRP00000022438	ENSSGRP00000028793	Mitogen-activated protein kinase kinase 4a.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.909
ENSSGRP00000022438	LOC107588610	ENSSGRP00000022438	ENSSGRP00000071134	Mitogen-activated protein kinase kinase 4a.	Mitogen-activated protein kinase 8B.	0.908