(80 nodes) Signaling by BMP, and TGF-beta propeptide network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000001974	Bone morphogenetic protein 7-like. (392 aa)
	ENSSGRP00000003135	annotation not available (218 aa)
	ENSSGRP00000004828	Bone morphogenetic protein 2-like. (346 aa)
	LOC107580862	BMP and activin membrane-bound inhibitor homolog. (148 aa)
	LOC107580985	Noggin-2-like. (216 aa)
	LOC107577119	Bone morphogenetic protein 2-like. (424 aa)
	LOC107572302	Activin receptor type-2A-like. (645 aa)
	ENSSGRP00000011803	Bone morphogenetic protein 2-like. (383 aa)
	LOC107602431	Growth/differentiation factor 2-like isoform X1. (399 aa)
	LOC107570535	Activin receptor type-1-like isoform X1. (497 aa)
	LOC107574503	Gremlin-2-like. (166 aa)
	ENSSGRP00000022067	Bone morphogenetic protein 2-like. (332 aa)
	LOC107581671	Noggin-3-like. (223 aa)
	LOC107570723	Bone morphogenetic protein 10-like. (472 aa)
	LOC107551190	Growth/differentiation factor 6-A-like. (405 aa)
	ENSSGRP00000029033	Growth differentiation factor 2. (340 aa)
	LOC107566293	Bone morphogenetic protein 2-like. (424 aa)
	bmp5	Bone morphogenetic protein 5. (443 aa)
	LOC107555441	Bone morphogenetic protein receptor type-2-like isoform X1. (1018 aa)
	LOC107594551	Bone morphogenetic protein receptor type-1B-like. (545 aa)
	ENSSGRP00000031155	Activin receptor type-1-like isoform X1. (537 aa)
	LOC107584759	Bone morphogenetic protein receptor type-2-like. (1008 aa)
	LOC107557104	Bone morphogenetic protein 10-like. (491 aa)
	LOC107568055	Bone morphogenetic protein 7-like. (420 aa)
	LOC107552890	Bone morphogenetic protein 2-like. (388 aa)
	ENSSGRP00000037486	annotation not available (117 aa)
	ENSSGRP00000037490	Bone morphogenetic protein receptor type-1B-like. (146 aa)
	ENSSGRP00000038709	Activin receptor type-2A-like isoform X1. (499 aa)
	bmp6	Bone morphogenetic protein 6 isoform X1. (416 aa)
	LOC107587642	Growth/differentiation factor 5-like. (499 aa)
	ENSSGRP00000041345	Chordin-like. (861 aa)
	LOC107556646	Noggin-2. (211 aa)
	LOC107563048	Bone morphogenetic protein receptor type-1A-like isoform X1. (539 aa)
	ENSSGRP00000044940	Gremlin-1-like. (168 aa)
	BMPR1A	Bone morphogenetic protein receptor type 1A. (531 aa)
	LOC107558294	Activin receptor type-2B-like. (508 aa)
	LOC107566874	Noggin-3. (223 aa)
	NOG	Noggin-1. (217 aa)
	LOC107600621	Growth/differentiation factor 6-A. (405 aa)
	LOC107601072	Activin receptor type-2A-like. (544 aa)
	LOC107597351	Bone morphogenetic protein 10-like. (493 aa)
	LOC107601571	Noggin-1-like. (217 aa)
	GREM1	Gremlin-1-like. (177 aa)
	LOC107602619	Activin receptor type-1-like. (506 aa)
	bmp2	Bone morphogenetic protein 2. (388 aa)
	LOC107563639	Activin receptor type-1-like. (486 aa)
	ENSSGRP00000064974	Noggin-2-like. (211 aa)
	LOC107593012	Bone morphogenetic protein receptor type-2-like. (1085 aa)
	LOC107570400	Gremlin-2-like. (166 aa)
	LOC107557245	Bone morphogenetic protein 7-like isoform X1. (420 aa)
	LOC107558980	Bone morphogenetic protein receptor type-1B-like. (552 aa)
	LOC107583498	Gremlin-2-like. (194 aa)
	BMP4	Bone morphogenetic protein 4-like. (400 aa)
	LOC107596296	Bone morphogenetic protein 2-like. (384 aa)
	ENSSGRP00000079833	Bone morphogenetic protein receptor type-1B-like. (429 aa)
	LOC107582766	Bone morphogenetic protein receptor type-1A-like. (535 aa)
	LOC107563371	Growth/differentiation factor 6-A-like. (425 aa)
	LOC107594862	Growth/differentiation factor 6-A-like. (425 aa)
	LOC107563717	Growth/differentiation factor 6-B-like. (416 aa)
	GREM1-2	Gremlin-1-like. (174 aa)
	LOC107554709	Growth/differentiation factor 9-like. (423 aa)
	ENSSGRP00000089801	Bone morphogenetic protein 4. (193 aa)
	ENSSGRP00000091028	Bone morphogenetic protein 5-like. (353 aa)
	LOC107564489	Bone morphogenetic protein 8A-like. (456 aa)
	ENSSGRP00000100338	Bone morphogenetic protein receptor type-1A-like. (544 aa)
	LOC107595463	Growth/differentiation factor 5-like. (491 aa)
	ENSSGRP00000102172	annotation not available (458 aa)
	ENSSGRP00000102185	annotation not available (393 aa)
	ENSSGRP00000102286	Bone morphogenetic protein 7a. (403 aa)
	LOC107559606	Growth/differentiation factor 9-like. (427 aa)
	ENSSGRP00000102767	Activin A receptor type 2Aa. (502 aa)
	LOC107556408	Bone morphogenetic protein 8A-like. (456 aa)
	chrd	Chordin. (938 aa)
	LOC107596462	Bone morphogenetic protein 15-like. (384 aa)
	LOC107592104	Growth/differentiation factor 6-B. (415 aa)
	LOC107593250	Bone morphogenetic protein 2-like. (411 aa)
	LOC107557510	Bone morphogenetic protein 15-like. (384 aa)
	bmpr2	Bone morphogenetic protein receptor type-2 isoform X1. (1064 aa)
	LOC107588871	Activin receptor type-1-like isoform X1. (504 aa)
	LOC107565994	Bone morphogenetic protein 7-like. (427 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMPR1A	ENSSGRP00000078686	ENSSGRP00000045284	Bone morphogenetic protein 4-like.	Bone morphogenetic protein receptor type 1A.	0.757
BMP4	ENSSGRP00000001974	ENSSGRP00000078686	ENSSGRP00000001974	Bone morphogenetic protein 4-like.	Bone morphogenetic protein 7-like.	0.546
BMP4	ENSSGRP00000031155	ENSSGRP00000078686	ENSSGRP00000031155	Bone morphogenetic protein 4-like.	Activin receptor type-1-like isoform X1.	0.859
BMP4	ENSSGRP00000037486	ENSSGRP00000078686	ENSSGRP00000037486	Bone morphogenetic protein 4-like.	annotation not available	0.746
BMP4	ENSSGRP00000037490	ENSSGRP00000078686	ENSSGRP00000037490	Bone morphogenetic protein 4-like.	Bone morphogenetic protein receptor type-1B-like.	0.973
BMP4	ENSSGRP00000038709	ENSSGRP00000078686	ENSSGRP00000038709	Bone morphogenetic protein 4-like.	Activin receptor type-2A-like isoform X1.	0.972
BMP4	ENSSGRP00000041345	ENSSGRP00000078686	ENSSGRP00000041345	Bone morphogenetic protein 4-like.	Chordin-like.	0.907
BMP4	ENSSGRP00000044940	ENSSGRP00000078686	ENSSGRP00000044940	Bone morphogenetic protein 4-like.	Gremlin-1-like.	0.794
BMP4	ENSSGRP00000064974	ENSSGRP00000078686	ENSSGRP00000064974	Bone morphogenetic protein 4-like.	Noggin-2-like.	0.855
BMP4	ENSSGRP00000079833	ENSSGRP00000078686	ENSSGRP00000079833	Bone morphogenetic protein 4-like.	Bone morphogenetic protein receptor type-1B-like.	0.984
BMP4	ENSSGRP00000091028	ENSSGRP00000078686	ENSSGRP00000091028	Bone morphogenetic protein 4-like.	Bone morphogenetic protein 5-like.	0.562
BMP4	ENSSGRP00000100338	ENSSGRP00000078686	ENSSGRP00000100338	Bone morphogenetic protein 4-like.	Bone morphogenetic protein receptor type-1A-like.	0.984
BMP4	ENSSGRP00000102172	ENSSGRP00000078686	ENSSGRP00000102172	Bone morphogenetic protein 4-like.	annotation not available	0.613
BMP4	ENSSGRP00000102185	ENSSGRP00000078686	ENSSGRP00000102185	Bone morphogenetic protein 4-like.	annotation not available	0.613
BMP4	ENSSGRP00000102286	ENSSGRP00000078686	ENSSGRP00000102286	Bone morphogenetic protein 4-like.	Bone morphogenetic protein 7a.	0.546
BMP4	ENSSGRP00000102767	ENSSGRP00000078686	ENSSGRP00000102767	Bone morphogenetic protein 4-like.	Activin A receptor type 2Aa.	0.740
BMP4	GREM1	ENSSGRP00000078686	ENSSGRP00000052726	Bone morphogenetic protein 4-like.	Gremlin-1-like.	0.749
BMP4	GREM1-2	ENSSGRP00000078686	ENSSGRP00000087686	Bone morphogenetic protein 4-like.	Gremlin-1-like.	0.749
BMP4	LOC107555441	ENSSGRP00000078686	ENSSGRP00000030898	Bone morphogenetic protein 4-like.	Bone morphogenetic protein receptor type-2-like isoform X1.	0.969
BMP4	LOC107556646	ENSSGRP00000078686	ENSSGRP00000042246	Bone morphogenetic protein 4-like.	Noggin-2.	0.855