(12 nodes) Heteromeric SMAD protein complex, and Domain of unknown function (DUF3480) network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	smad3	Mothers against decapentaplegic homolog 3. (425 aa)
	ENSSGRP00000021965	Zinc finger FYVE domain-containing protein 9-like isoform X1. (1167 aa)
	ENSSGRP00000029005	annotation not available (67 aa)
	ENSSGRP00000029007	E3 ubiquitin-protein ligase SMURF2-like. (359 aa)
	smad2	Mothers against decapentaplegic homolog 2. (468 aa)
	SMAD9	Mothers against decapentaplegic homolog 9-like isoform X1. (434 aa)
	LOC107583766	Mothers against decapentaplegic homolog 6-like. (487 aa)
	Smad7	Mothers against decapentaplegic homolog 7. (182 aa)
	ENSSGRP00000076363	Mothers against decapentaplegic homolog 4-like isoform X1. (573 aa)
	ENSSGRP00000098989	Mothers against decapentaplegic homolog 4-like. (169 aa)
	ENSSGRP00000100725	MAD, mothers against decapentaplegic interacting protein. (1347 aa)
	ENSSGRP00000108174	Mothers against decapentaplegic homolog 3-like. (68 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000021965	ENSSGRP00000076363	ENSSGRP00000021965	ENSSGRP00000076363	Zinc finger FYVE domain-containing protein 9-like isoform X1.	Mothers against decapentaplegic homolog 4-like isoform X1.	0.587
ENSSGRP00000021965	ENSSGRP00000098989	ENSSGRP00000021965	ENSSGRP00000098989	Zinc finger FYVE domain-containing protein 9-like isoform X1.	Mothers against decapentaplegic homolog 4-like.	0.587
ENSSGRP00000021965	ENSSGRP00000108174	ENSSGRP00000021965	ENSSGRP00000108174	Zinc finger FYVE domain-containing protein 9-like isoform X1.	Mothers against decapentaplegic homolog 3-like.	0.974
ENSSGRP00000021965	LOC107583766	ENSSGRP00000021965	ENSSGRP00000049337	Zinc finger FYVE domain-containing protein 9-like isoform X1.	Mothers against decapentaplegic homolog 6-like.	0.530
ENSSGRP00000021965	SMAD9	ENSSGRP00000021965	ENSSGRP00000044683	Zinc finger FYVE domain-containing protein 9-like isoform X1.	Mothers against decapentaplegic homolog 9-like isoform X1.	0.601
ENSSGRP00000021965	Smad7	ENSSGRP00000021965	ENSSGRP00000050201	Zinc finger FYVE domain-containing protein 9-like isoform X1.	Mothers against decapentaplegic homolog 7.	0.530
ENSSGRP00000021965	smad2	ENSSGRP00000021965	ENSSGRP00000033834	Zinc finger FYVE domain-containing protein 9-like isoform X1.	Mothers against decapentaplegic homolog 2.	0.974
ENSSGRP00000021965	smad3	ENSSGRP00000021965	ENSSGRP00000003942	Zinc finger FYVE domain-containing protein 9-like isoform X1.	Mothers against decapentaplegic homolog 3.	0.974
ENSSGRP00000029005	ENSSGRP00000076363	ENSSGRP00000029005	ENSSGRP00000076363	annotation not available	Mothers against decapentaplegic homolog 4-like isoform X1.	0.686
ENSSGRP00000029005	ENSSGRP00000098989	ENSSGRP00000029005	ENSSGRP00000098989	annotation not available	Mothers against decapentaplegic homolog 4-like.	0.686
ENSSGRP00000029005	ENSSGRP00000108174	ENSSGRP00000029005	ENSSGRP00000108174	annotation not available	Mothers against decapentaplegic homolog 3-like.	0.749
ENSSGRP00000029005	LOC107583766	ENSSGRP00000029005	ENSSGRP00000049337	annotation not available	Mothers against decapentaplegic homolog 6-like.	0.830
ENSSGRP00000029005	SMAD9	ENSSGRP00000029005	ENSSGRP00000044683	annotation not available	Mothers against decapentaplegic homolog 9-like isoform X1.	0.697
ENSSGRP00000029005	Smad7	ENSSGRP00000029005	ENSSGRP00000050201	annotation not available	Mothers against decapentaplegic homolog 7.	0.905
ENSSGRP00000029005	smad2	ENSSGRP00000029005	ENSSGRP00000033834	annotation not available	Mothers against decapentaplegic homolog 2.	0.862
ENSSGRP00000029005	smad3	ENSSGRP00000029005	ENSSGRP00000003942	annotation not available	Mothers against decapentaplegic homolog 3.	0.779
ENSSGRP00000029007	ENSSGRP00000076363	ENSSGRP00000029007	ENSSGRP00000076363	E3 ubiquitin-protein ligase SMURF2-like.	Mothers against decapentaplegic homolog 4-like isoform X1.	0.686
ENSSGRP00000029007	ENSSGRP00000098989	ENSSGRP00000029007	ENSSGRP00000098989	E3 ubiquitin-protein ligase SMURF2-like.	Mothers against decapentaplegic homolog 4-like.	0.686
ENSSGRP00000029007	ENSSGRP00000108174	ENSSGRP00000029007	ENSSGRP00000108174	E3 ubiquitin-protein ligase SMURF2-like.	Mothers against decapentaplegic homolog 3-like.	0.749
ENSSGRP00000029007	LOC107583766	ENSSGRP00000029007	ENSSGRP00000049337	E3 ubiquitin-protein ligase SMURF2-like.	Mothers against decapentaplegic homolog 6-like.	0.938