(13 nodes) Heteromeric SMAD protein complex, and c-SKI Smad4 binding domain network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107557528	Ski-like protein. (728 aa)
	LOC107559658	Mothers against decapentaplegic homolog 4 isoform X1. (550 aa)
	LOC107599811	Ski oncogene-like. (726 aa)
	LOC107548407	Ski oncogene-like. (726 aa)
	ENSSGRP00000022575	SMAD family member 4a. (499 aa)
	ENSSGRP00000036217	annotation not available (113 aa)
	ENSSGRP00000036219	Mothers against decapentaplegic homolog 1-like. (181 aa)
	LOC107550085	Mothers against decapentaplegic homolog 4-like isoform X1. (571 aa)
	LOC107583760	Mothers against decapentaplegic homolog 3-like. (453 aa)
	ENSSGRP00000062617	Mothers against decapentaplegic homolog 1. (458 aa)
	LOC107591339	Ski-like protein isoform X1. (727 aa)
	LOC107553101	Mothers against decapentaplegic homolog 3. (439 aa)
	ENSSGRP00000089762	Si:dkey-222b8.1. (527 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000022575	ENSSGRP00000036217	ENSSGRP00000022575	ENSSGRP00000036217	SMAD family member 4a.	annotation not available	0.781
ENSSGRP00000022575	ENSSGRP00000036219	ENSSGRP00000022575	ENSSGRP00000036219	SMAD family member 4a.	Mothers against decapentaplegic homolog 1-like.	0.781
ENSSGRP00000022575	ENSSGRP00000062617	ENSSGRP00000022575	ENSSGRP00000062617	SMAD family member 4a.	Mothers against decapentaplegic homolog 1.	0.822
ENSSGRP00000022575	LOC107548407	ENSSGRP00000022575	ENSSGRP00000020651	SMAD family member 4a.	Ski oncogene-like.	0.888
ENSSGRP00000022575	LOC107553101	ENSSGRP00000022575	ENSSGRP00000070223	SMAD family member 4a.	Mothers against decapentaplegic homolog 3.	0.853
ENSSGRP00000022575	LOC107557528	ENSSGRP00000022575	ENSSGRP00000004436	SMAD family member 4a.	Ski-like protein.	0.775
ENSSGRP00000022575	LOC107583760	ENSSGRP00000022575	ENSSGRP00000049287	SMAD family member 4a.	Mothers against decapentaplegic homolog 3-like.	0.813
ENSSGRP00000022575	LOC107591339	ENSSGRP00000022575	ENSSGRP00000064182	SMAD family member 4a.	Ski-like protein isoform X1.	0.775
ENSSGRP00000022575	LOC107599811	ENSSGRP00000022575	ENSSGRP00000013140	SMAD family member 4a.	Ski oncogene-like.	0.888
ENSSGRP00000036217	ENSSGRP00000022575	ENSSGRP00000036217	ENSSGRP00000022575	annotation not available	SMAD family member 4a.	0.781
ENSSGRP00000036217	ENSSGRP00000036219	ENSSGRP00000036217	ENSSGRP00000036219	annotation not available	Mothers against decapentaplegic homolog 1-like.	0.498
ENSSGRP00000036217	ENSSGRP00000089762	ENSSGRP00000036217	ENSSGRP00000089762	annotation not available	Si:dkey-222b8.1.	0.750
ENSSGRP00000036217	LOC107548407	ENSSGRP00000036217	ENSSGRP00000020651	annotation not available	Ski oncogene-like.	0.743
ENSSGRP00000036217	LOC107550085	ENSSGRP00000036217	ENSSGRP00000045624	annotation not available	Mothers against decapentaplegic homolog 4-like isoform X1.	0.750
ENSSGRP00000036217	LOC107553101	ENSSGRP00000036217	ENSSGRP00000070223	annotation not available	Mothers against decapentaplegic homolog 3.	0.541
ENSSGRP00000036217	LOC107557528	ENSSGRP00000036217	ENSSGRP00000004436	annotation not available	Ski-like protein.	0.696
ENSSGRP00000036217	LOC107559658	ENSSGRP00000036217	ENSSGRP00000007947	annotation not available	Mothers against decapentaplegic homolog 4 isoform X1.	0.781
ENSSGRP00000036217	LOC107583760	ENSSGRP00000036217	ENSSGRP00000049287	annotation not available	Mothers against decapentaplegic homolog 3-like.	0.546
ENSSGRP00000036217	LOC107591339	ENSSGRP00000036217	ENSSGRP00000064182	annotation not available	Ski-like protein isoform X1.	0.696
ENSSGRP00000036217	LOC107599811	ENSSGRP00000036217	ENSSGRP00000013140	annotation not available	Ski oncogene-like.	0.743