(5 nodes) Hippo signaling network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000013771	WW domain containing transcription regulator 1. (401 aa)
	ENSSGRP00000044184	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like. (1060 aa)
	LOC107602931	Protein salvador homolog 1-like. (395 aa)
	LOC107585392	MOB kinase activator 1B-like isoform X1. (216 aa)
	LOC107556381	Serine/threonine-protein kinase 3 isoform X1. (492 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000013771	ENSSGRP00000044184	ENSSGRP00000013771	ENSSGRP00000044184	WW domain containing transcription regulator 1.	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	0.944
ENSSGRP00000013771	LOC107556381	ENSSGRP00000013771	ENSSGRP00000100374	WW domain containing transcription regulator 1.	Serine/threonine-protein kinase 3 isoform X1.	0.930
ENSSGRP00000013771	LOC107585392	ENSSGRP00000013771	ENSSGRP00000065245	WW domain containing transcription regulator 1.	MOB kinase activator 1B-like isoform X1.	0.743
ENSSGRP00000013771	LOC107602931	ENSSGRP00000013771	ENSSGRP00000046762	WW domain containing transcription regulator 1.	Protein salvador homolog 1-like.	0.803
ENSSGRP00000044184	ENSSGRP00000013771	ENSSGRP00000044184	ENSSGRP00000013771	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	WW domain containing transcription regulator 1.	0.944
ENSSGRP00000044184	LOC107556381	ENSSGRP00000044184	ENSSGRP00000100374	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	Serine/threonine-protein kinase 3 isoform X1.	0.933
ENSSGRP00000044184	LOC107585392	ENSSGRP00000044184	ENSSGRP00000065245	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	MOB kinase activator 1B-like isoform X1.	0.944
ENSSGRP00000044184	LOC107602931	ENSSGRP00000044184	ENSSGRP00000046762	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	Protein salvador homolog 1-like.	0.931
LOC107556381	ENSSGRP00000013771	ENSSGRP00000100374	ENSSGRP00000013771	Serine/threonine-protein kinase 3 isoform X1.	WW domain containing transcription regulator 1.	0.930
LOC107556381	ENSSGRP00000044184	ENSSGRP00000100374	ENSSGRP00000044184	Serine/threonine-protein kinase 3 isoform X1.	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	0.933
LOC107556381	LOC107585392	ENSSGRP00000100374	ENSSGRP00000065245	Serine/threonine-protein kinase 3 isoform X1.	MOB kinase activator 1B-like isoform X1.	0.973
LOC107556381	LOC107602931	ENSSGRP00000100374	ENSSGRP00000046762	Serine/threonine-protein kinase 3 isoform X1.	Protein salvador homolog 1-like.	0.981
LOC107585392	ENSSGRP00000013771	ENSSGRP00000065245	ENSSGRP00000013771	MOB kinase activator 1B-like isoform X1.	WW domain containing transcription regulator 1.	0.743
LOC107585392	ENSSGRP00000044184	ENSSGRP00000065245	ENSSGRP00000044184	MOB kinase activator 1B-like isoform X1.	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	0.944
LOC107585392	LOC107556381	ENSSGRP00000065245	ENSSGRP00000100374	MOB kinase activator 1B-like isoform X1.	Serine/threonine-protein kinase 3 isoform X1.	0.973
LOC107585392	LOC107602931	ENSSGRP00000065245	ENSSGRP00000046762	MOB kinase activator 1B-like isoform X1.	Protein salvador homolog 1-like.	0.814
LOC107602931	ENSSGRP00000013771	ENSSGRP00000046762	ENSSGRP00000013771	Protein salvador homolog 1-like.	WW domain containing transcription regulator 1.	0.803
LOC107602931	ENSSGRP00000044184	ENSSGRP00000046762	ENSSGRP00000044184	Protein salvador homolog 1-like.	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	0.931
LOC107602931	LOC107556381	ENSSGRP00000046762	ENSSGRP00000100374	Protein salvador homolog 1-like.	Serine/threonine-protein kinase 3 isoform X1.	0.981
LOC107602931	LOC107585392	ENSSGRP00000046762	ENSSGRP00000065245	Protein salvador homolog 1-like.	MOB kinase activator 1B-like isoform X1.	0.814