(35 nodes) Papain family cysteine protease, and Aspartyl protease network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000004167	Cathepsin D-like. (364 aa)
	ENSSGRP00000006432	Cathepsin B-like. (325 aa)
	ENSSGRP00000008376	Cathepsin B-like. (328 aa)
	ENSSGRP00000011074	annotation not available (359 aa)
	LOC107592770	Cathepsin B-like isoform X1. (330 aa)
	LOC107557611	Cathepsin L1-like. (358 aa)
	LOC107570111	Dipeptidyl peptidase 1-like. (455 aa)
	LOC107569115	Cathepsin E-A-like. (405 aa)
	ENSSGRP00000023629	annotation not available (292 aa)
	LOC107587480	Interferon-induced transmembrane protein 1-like. (118 aa)
	ENSSGRP00000030954	LOW QUALITY PROTEIN: cathepsin D-like. (404 aa)
	ENSSGRP00000039008	Lectin, mannose-binding 1. (492 aa)
	ENSSGRP00000041320	Cathepsin L1-like. (317 aa)
	LOC107559296	Cathepsin F-like. (473 aa)
	ENSSGRP00000049782	Coagulation factor VIII, procoagulant component. (1564 aa)
	ENSSGRP00000057181	Cathepsin L1-like isoform X1. (339 aa)
	LOC107558840	Dipeptidyl peptidase 1-like. (455 aa)
	ctsh	Pro-cathepsin H. (330 aa)
	ENSSGRP00000067052	Cathepsin L1-like. (244 aa)
	LOC107590952	Cathepsin L1-like. (334 aa)
	ctsd	Cathepsin D. (402 aa)
	ENSSGRP00000073424	annotation not available (104 aa)
	LOC107596856	Cathepsin Z-like. (301 aa)
	ENSSGRP00000078931	annotation not available (196 aa)
	LOC107587086	Cathepsin F-like isoform X1. (473 aa)
	ENSSGRP00000088488	Cathepsin Z. (246 aa)
	LOC107554171	Cathepsin Z-like. (301 aa)
	ENSSGRP00000089580	Cathepsin H. (250 aa)
	ENSSGRP00000089581	Pro-cathepsin H-like. (330 aa)
	LOC107597985	Cathepsin S-like. (331 aa)
	ENSSGRP00000092557	annotation not available (1327 aa)
	ENSSGRP00000098896	Lectin, mannose-binding, 1. (494 aa)
	ENSSGRP00000100482	Cathepsin L1-like. (339 aa)
	ENSSGRP00000109011	annotation not available (71 aa)
	Mcfd2	Multiple coagulation factor deficiency protein 2 isoform X1. (92 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000004167	ENSSGRP00000006432	ENSSGRP00000004167	ENSSGRP00000006432	Cathepsin D-like.	Cathepsin B-like.	0.724
ENSSGRP00000004167	ENSSGRP00000008376	ENSSGRP00000004167	ENSSGRP00000008376	Cathepsin D-like.	Cathepsin B-like.	0.801
ENSSGRP00000004167	ENSSGRP00000030954	ENSSGRP00000004167	ENSSGRP00000030954	Cathepsin D-like.	LOW QUALITY PROTEIN: cathepsin D-like.	0.902
ENSSGRP00000004167	ENSSGRP00000041320	ENSSGRP00000004167	ENSSGRP00000041320	Cathepsin D-like.	Cathepsin L1-like.	0.806
ENSSGRP00000004167	ENSSGRP00000057181	ENSSGRP00000004167	ENSSGRP00000057181	Cathepsin D-like.	Cathepsin L1-like isoform X1.	0.788
ENSSGRP00000004167	ENSSGRP00000067052	ENSSGRP00000004167	ENSSGRP00000067052	Cathepsin D-like.	Cathepsin L1-like.	0.890
ENSSGRP00000004167	ENSSGRP00000078931	ENSSGRP00000004167	ENSSGRP00000078931	Cathepsin D-like.	annotation not available	0.565
ENSSGRP00000004167	ENSSGRP00000088488	ENSSGRP00000004167	ENSSGRP00000088488	Cathepsin D-like.	Cathepsin Z.	0.584
ENSSGRP00000004167	ENSSGRP00000089580	ENSSGRP00000004167	ENSSGRP00000089580	Cathepsin D-like.	Cathepsin H.	0.634
ENSSGRP00000004167	ENSSGRP00000089581	ENSSGRP00000004167	ENSSGRP00000089581	Cathepsin D-like.	Pro-cathepsin H-like.	0.634
ENSSGRP00000004167	ENSSGRP00000100482	ENSSGRP00000004167	ENSSGRP00000100482	Cathepsin D-like.	Cathepsin L1-like.	0.829
ENSSGRP00000004167	LOC107554171	ENSSGRP00000004167	ENSSGRP00000088497	Cathepsin D-like.	Cathepsin Z-like.	0.584
ENSSGRP00000004167	LOC107557611	ENSSGRP00000004167	ENSSGRP00000012258	Cathepsin D-like.	Cathepsin L1-like.	0.829
ENSSGRP00000004167	LOC107558840	ENSSGRP00000004167	ENSSGRP00000060290	Cathepsin D-like.	Dipeptidyl peptidase 1-like.	0.610
ENSSGRP00000004167	LOC107559296	ENSSGRP00000004167	ENSSGRP00000045457	Cathepsin D-like.	Cathepsin F-like.	0.616
ENSSGRP00000004167	LOC107570111	ENSSGRP00000004167	ENSSGRP00000020113	Cathepsin D-like.	Dipeptidyl peptidase 1-like.	0.610
ENSSGRP00000004167	LOC107587086	ENSSGRP00000004167	ENSSGRP00000082095	Cathepsin D-like.	Cathepsin F-like isoform X1.	0.616
ENSSGRP00000004167	LOC107590952	ENSSGRP00000004167	ENSSGRP00000067890	Cathepsin D-like.	Cathepsin L1-like.	0.806
ENSSGRP00000004167	LOC107592770	ENSSGRP00000004167	ENSSGRP00000012009	Cathepsin D-like.	Cathepsin B-like isoform X1.	0.724
ENSSGRP00000004167	LOC107596856	ENSSGRP00000004167	ENSSGRP00000074208	Cathepsin D-like.	Cathepsin Z-like.	0.584