(50 nodes) Tight junction network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107563996	Claudin-4-like. (211 aa)
	LOC107586808	Claudin-11-like. (217 aa)
	ENSSGRP00000002896	Claudin-1-like. (150 aa)
	LOC107579975	Claudin-3-like. (214 aa)
	LOC107583065	Claudin-4-like. (211 aa)
	LOC107558842	Claudin-8-like. (293 aa)
	LOC107578419	Claudin-8-like. (270 aa)
	LOC107585751	Claudin-8-like. (293 aa)
	LOC107575918	Claudin-3-like. (218 aa)
	ENSSGRP00000017422	Claudin-4-like. (180 aa)
	LOC107576154	Putative claudin-24. (228 aa)
	LOC107552167	Claudin-4-like. (215 aa)
	LOC107560284	Claudin-7-A-like. (212 aa)
	ENSSGRP00000032737	Claudin-23-like. (222 aa)
	LOC107565733	Claudin-19-like isoform X1. (218 aa)
	LOC107552232	Claudin-like protein ZF-A9 isoform X1. (209 aa)
	LOC107551262	Claudin-4-like. (209 aa)
	LOC107551266	Claudin-4-like. (206 aa)
	LOC107551269	Claudin-3-like. (215 aa)
	LOC107550596	Claudin-11-like isoform X1. (215 aa)
	LOC107558847	Claudin-8-like. (228 aa)
	CLDN20	Claudin-20-like. (243 aa)
	LOC107602706	Claudin-4-like. (216 aa)
	LOC107592677	Tight junction protein ZO-2-like. (1251 aa)
	LOC107553040	Claudin-4-like. (215 aa)
	LOC107598663	Claudin-3-like. (215 aa)
	ENSSGRP00000060497	Claudin-4-like. (111 aa)
	LOC107598569	Claudin-4-like. (206 aa)
	LOC107598615	Claudin-4-like. (155 aa)
	LOC107598666	Claudin-4-like. (191 aa)
	LOC107598571	Claudin-4-like. (209 aa)
	ENSSGRP00000060528	Claudin-4-like. (125 aa)
	LOC107572167	Claudin-7-A. (213 aa)
	LOC107552392	Putative claudin-24. (220 aa)
	CLDN20-2	Claudin-20-like. (243 aa)
	LOC107567186	Claudin-like protein ZF-A89. (208 aa)
	LOC107567167	Claudin-like protein ZF-A89. (210 aa)
	LOC107567187	Claudin-3-like. (218 aa)
	Cldn11	Claudin-11. (221 aa)
	LOC107582397	Claudin-19-like isoform X1. (218 aa)
	LOC107567749	Claudin-5-like. (217 aa)
	LOC107599648	Putative claudin-24. (220 aa)
	ENSSGRP00000091729	Claudin-23-like. (232 aa)
	LOC107586547	Claudin-11-like. (215 aa)
	LOC107586151	Claudin-7-B-like isoform X1. (209 aa)
	ENSSGRP00000103554	Claudin-18-like. (213 aa)
	LOC107548150	Claudin-3-like. (214 aa)
	ENSSGRP00000104380	Claudin-4-like. (201 aa)
	LOC107548211	Claudin-like protein ZF-A89. (208 aa)
	ENSSGRP00000104763	Claudin-15-like. (207 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN20	CLDN20-2	ENSSGRP00000055066	ENSSGRP00000068192	Claudin-20-like.	Claudin-20-like.	0.652
CLDN20	Cldn11	ENSSGRP00000055066	ENSSGRP00000071776	Claudin-20-like.	Claudin-11.	0.673
CLDN20	ENSSGRP00000002896	ENSSGRP00000055066	ENSSGRP00000002896	Claudin-20-like.	Claudin-1-like.	0.679
CLDN20	ENSSGRP00000017422	ENSSGRP00000055066	ENSSGRP00000017422	Claudin-20-like.	Claudin-4-like.	0.657
CLDN20	ENSSGRP00000032737	ENSSGRP00000055066	ENSSGRP00000032737	Claudin-20-like.	Claudin-23-like.	0.746
CLDN20	ENSSGRP00000060497	ENSSGRP00000055066	ENSSGRP00000060497	Claudin-20-like.	Claudin-4-like.	0.657
CLDN20	ENSSGRP00000060528	ENSSGRP00000055066	ENSSGRP00000060528	Claudin-20-like.	Claudin-4-like.	0.657
CLDN20	ENSSGRP00000091729	ENSSGRP00000055066	ENSSGRP00000091729	Claudin-20-like.	Claudin-23-like.	0.746
CLDN20	ENSSGRP00000103554	ENSSGRP00000055066	ENSSGRP00000103554	Claudin-20-like.	Claudin-18-like.	0.681
CLDN20	ENSSGRP00000104380	ENSSGRP00000055066	ENSSGRP00000104380	Claudin-20-like.	Claudin-4-like.	0.657
CLDN20	ENSSGRP00000104763	ENSSGRP00000055066	ENSSGRP00000104763	Claudin-20-like.	Claudin-15-like.	0.665
CLDN20	LOC107548150	ENSSGRP00000055066	ENSSGRP00000104377	Claudin-20-like.	Claudin-3-like.	0.666
CLDN20	LOC107548211	ENSSGRP00000055066	ENSSGRP00000104386	Claudin-20-like.	Claudin-like protein ZF-A89.	0.657
CLDN20	LOC107550596	ENSSGRP00000055066	ENSSGRP00000042904	Claudin-20-like.	Claudin-11-like isoform X1.	0.673
CLDN20	LOC107551262	ENSSGRP00000055066	ENSSGRP00000037873	Claudin-20-like.	Claudin-4-like.	0.657
CLDN20	LOC107551266	ENSSGRP00000055066	ENSSGRP00000037874	Claudin-20-like.	Claudin-4-like.	0.657
CLDN20	LOC107551269	ENSSGRP00000055066	ENSSGRP00000037877	Claudin-20-like.	Claudin-3-like.	0.666
CLDN20	LOC107552167	ENSSGRP00000055066	ENSSGRP00000024082	Claudin-20-like.	Claudin-4-like.	0.671
CLDN20	LOC107552232	ENSSGRP00000055066	ENSSGRP00000037242	Claudin-20-like.	Claudin-like protein ZF-A9 isoform X1.	0.657
CLDN20	LOC107552392	ENSSGRP00000055066	ENSSGRP00000066089	Claudin-20-like.	Putative claudin-24.	0.676