(24 nodes) HDR through Single Strand Annealing (SSA), and Histone H3-T11 phosphorylation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rmi2	RecQ-mediated genome instability protein 2. (149 aa)
	ENSSGRP00000009235	annotation not available (89 aa)
	ENSSGRP00000009602	Methionine sulfoxide reductase B1b. (255 aa)
	LOC107562955	Replication protein A 70 kDa DNA-binding subunit isoform X1. (603 aa)
	LOC107598208	Replication protein A 14 kDa subunit-like. (121 aa)
	ENSSGRP00000024514	ATR serine/threonine kinase. (1911 aa)
	ENSSGRP00000039659	annotation not available (116 aa)
	top3a	DNA topoisomerase 3-alpha. (996 aa)
	LOC107586922	ATR-interacting protein-like. (753 aa)
	CLSPN	Claspin-like. (895 aa)
	ENSSGRP00000064987	BLM RecQ like helicase. (597 aa)
	ENSSGRP00000068109	Methionine sulfoxide reductase B1b. (410 aa)
	ENSSGRP00000070027	RecQ-mediated genome instability protein 1-like. (544 aa)
	ENSSGRP00000074465	DNA topoisomerase III beta. (808 aa)
	LOC107548543	Replication protein A 70 kDa DNA-binding subunit-like. (641 aa)
	ENSSGRP00000077312	ATR-interacting protein-like. (759 aa)
	Rpa2	Replication protein A 32 kDa subunit isoform X1. (349 aa)
	LOC107568286	Replication protein A 14 kDa subunit-like. (121 aa)
	ENSSGRP00000084920	Exonuclease 3'-5' domain-containing protein 2-like. (625 aa)
	CLSPN-2	Claspin isoform X1. (1271 aa)
	LOC107553162	Beta-2-microglobulin-like. (115 aa)
	ENSSGRP00000096842	annotation not available (127 aa)
	ENSSGRP00000097497	Checkpoint kinase 1. (411 aa)
	ENSSGRP00000107162	Tudor domain containing 3. (720 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLSPN	ENSSGRP00000009235	ENSSGRP00000063915	ENSSGRP00000009235	Claspin-like.	annotation not available	0.953
CLSPN	ENSSGRP00000009602	ENSSGRP00000063915	ENSSGRP00000009602	Claspin-like.	Methionine sulfoxide reductase B1b.	0.894
CLSPN	ENSSGRP00000024514	ENSSGRP00000063915	ENSSGRP00000024514	Claspin-like.	ATR serine/threonine kinase.	0.836
CLSPN	ENSSGRP00000039659	ENSSGRP00000063915	ENSSGRP00000039659	Claspin-like.	annotation not available	0.836
CLSPN	ENSSGRP00000064987	ENSSGRP00000063915	ENSSGRP00000064987	Claspin-like.	BLM RecQ like helicase.	0.673
CLSPN	ENSSGRP00000068109	ENSSGRP00000063915	ENSSGRP00000068109	Claspin-like.	Methionine sulfoxide reductase B1b.	0.894
CLSPN	ENSSGRP00000077312	ENSSGRP00000063915	ENSSGRP00000077312	Claspin-like.	ATR-interacting protein-like.	0.851
CLSPN	ENSSGRP00000084920	ENSSGRP00000063915	ENSSGRP00000084920	Claspin-like.	Exonuclease 3'-5' domain-containing protein 2-like.	0.519
CLSPN	ENSSGRP00000096842	ENSSGRP00000063915	ENSSGRP00000096842	Claspin-like.	annotation not available	0.445
CLSPN	ENSSGRP00000097497	ENSSGRP00000063915	ENSSGRP00000097497	Claspin-like.	Checkpoint kinase 1.	0.985
CLSPN	LOC107548543	ENSSGRP00000063915	ENSSGRP00000075795	Claspin-like.	Replication protein A 70 kDa DNA-binding subunit-like.	0.975
CLSPN	LOC107553162	ENSSGRP00000063915	ENSSGRP00000090843	Claspin-like.	Beta-2-microglobulin-like.	0.824
CLSPN	LOC107562955	ENSSGRP00000063915	ENSSGRP00000010771	Claspin-like.	Replication protein A 70 kDa DNA-binding subunit isoform X1.	0.975
CLSPN	LOC107568286	ENSSGRP00000063915	ENSSGRP00000084576	Claspin-like.	Replication protein A 14 kDa subunit-like.	0.953
CLSPN	LOC107586922	ENSSGRP00000063915	ENSSGRP00000051220	Claspin-like.	ATR-interacting protein-like.	0.851
CLSPN	LOC107598208	ENSSGRP00000063915	ENSSGRP00000015746	Claspin-like.	Replication protein A 14 kDa subunit-like.	0.953
CLSPN	Rpa2	ENSSGRP00000063915	ENSSGRP00000077944	Claspin-like.	Replication protein A 32 kDa subunit isoform X1.	0.824
CLSPN-2	ENSSGRP00000009235	ENSSGRP00000090497	ENSSGRP00000009235	Claspin isoform X1.	annotation not available	0.953
CLSPN-2	ENSSGRP00000009602	ENSSGRP00000090497	ENSSGRP00000009602	Claspin isoform X1.	Methionine sulfoxide reductase B1b.	0.894
CLSPN-2	ENSSGRP00000024514	ENSSGRP00000090497	ENSSGRP00000024514	Claspin isoform X1.	ATR serine/threonine kinase.	0.836