(14 nodes) Mixed, incl. RecQ family helicase-topoisomerase III complex, and DNA replication factor A complex network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rmi2	RecQ-mediated genome instability protein 2. (149 aa)
	LOC107562955	Replication protein A 70 kDa DNA-binding subunit isoform X1. (603 aa)
	LOC107598208	Replication protein A 14 kDa subunit-like. (121 aa)
	ENSSGRP00000039659	annotation not available (116 aa)
	top3a	DNA topoisomerase 3-alpha. (996 aa)
	LOC107586922	ATR-interacting protein-like. (753 aa)
	ENSSGRP00000064987	BLM RecQ like helicase. (597 aa)
	ENSSGRP00000068109	Methionine sulfoxide reductase B1b. (410 aa)
	ENSSGRP00000070027	RecQ-mediated genome instability protein 1-like. (544 aa)
	LOC107548543	Replication protein A 70 kDa DNA-binding subunit-like. (641 aa)
	Rpa2	Replication protein A 32 kDa subunit isoform X1. (349 aa)
	LOC107568286	Replication protein A 14 kDa subunit-like. (121 aa)
	LOC107553162	Beta-2-microglobulin-like. (115 aa)
	ENSSGRP00000096842	annotation not available (127 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000039659	ENSSGRP00000064987	ENSSGRP00000039659	ENSSGRP00000064987	annotation not available	BLM RecQ like helicase.	0.976
ENSSGRP00000039659	ENSSGRP00000068109	ENSSGRP00000039659	ENSSGRP00000068109	annotation not available	Methionine sulfoxide reductase B1b.	0.926
ENSSGRP00000039659	ENSSGRP00000070027	ENSSGRP00000039659	ENSSGRP00000070027	annotation not available	RecQ-mediated genome instability protein 1-like.	0.737
ENSSGRP00000039659	ENSSGRP00000096842	ENSSGRP00000039659	ENSSGRP00000096842	annotation not available	annotation not available	0.935
ENSSGRP00000039659	LOC107548543	ENSSGRP00000039659	ENSSGRP00000075795	annotation not available	Replication protein A 70 kDa DNA-binding subunit-like.	0.975
ENSSGRP00000039659	LOC107553162	ENSSGRP00000039659	ENSSGRP00000090843	annotation not available	Beta-2-microglobulin-like.	0.885
ENSSGRP00000039659	LOC107562955	ENSSGRP00000039659	ENSSGRP00000010771	annotation not available	Replication protein A 70 kDa DNA-binding subunit isoform X1.	0.975
ENSSGRP00000039659	LOC107568286	ENSSGRP00000039659	ENSSGRP00000084576	annotation not available	Replication protein A 14 kDa subunit-like.	0.587
ENSSGRP00000039659	LOC107586922	ENSSGRP00000039659	ENSSGRP00000051220	annotation not available	ATR-interacting protein-like.	0.981
ENSSGRP00000039659	LOC107598208	ENSSGRP00000039659	ENSSGRP00000015746	annotation not available	Replication protein A 14 kDa subunit-like.	0.587
ENSSGRP00000039659	Rpa2	ENSSGRP00000039659	ENSSGRP00000077944	annotation not available	Replication protein A 32 kDa subunit isoform X1.	0.885
ENSSGRP00000039659	rmi2	ENSSGRP00000039659	ENSSGRP00000004335	annotation not available	RecQ-mediated genome instability protein 2.	0.623
ENSSGRP00000039659	top3a	ENSSGRP00000039659	ENSSGRP00000045927	annotation not available	DNA topoisomerase 3-alpha.	0.864
ENSSGRP00000064987	ENSSGRP00000039659	ENSSGRP00000064987	ENSSGRP00000039659	BLM RecQ like helicase.	annotation not available	0.976
ENSSGRP00000064987	ENSSGRP00000068109	ENSSGRP00000064987	ENSSGRP00000068109	BLM RecQ like helicase.	Methionine sulfoxide reductase B1b.	0.938
ENSSGRP00000064987	ENSSGRP00000070027	ENSSGRP00000064987	ENSSGRP00000070027	BLM RecQ like helicase.	RecQ-mediated genome instability protein 1-like.	0.990
ENSSGRP00000064987	ENSSGRP00000096842	ENSSGRP00000064987	ENSSGRP00000096842	BLM RecQ like helicase.	annotation not available	0.980
ENSSGRP00000064987	LOC107548543	ENSSGRP00000064987	ENSSGRP00000075795	BLM RecQ like helicase.	Replication protein A 70 kDa DNA-binding subunit-like.	0.994
ENSSGRP00000064987	LOC107553162	ENSSGRP00000064987	ENSSGRP00000090843	BLM RecQ like helicase.	Beta-2-microglobulin-like.	0.914
ENSSGRP00000064987	LOC107562955	ENSSGRP00000064987	ENSSGRP00000010771	BLM RecQ like helicase.	Replication protein A 70 kDa DNA-binding subunit isoform X1.	0.994