(11 nodes) Mismatch repair complex network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PMS2	PMS1 homolog 2, mismatch repair system component. (430 aa)
	ENSSGRP00000024222	mutL homolog 3 (E. coli). (404 aa)
	msh3	DNA mismatch repair protein Msh3 isoform X1. (1090 aa)
	ENSSGRP00000040788	annotation not available (148 aa)
	LOC107550043	DNA mismatch repair protein Msh2-like. (936 aa)
	LOC107588437	DNA mismatch repair protein Msh6-like isoform X1. (1395 aa)
	mlh1	DNA mismatch repair protein MLH1. (724 aa)
	ENSSGRP00000059625	annotation not available (290 aa)
	LOC107594169	Mismatch repair endonuclease PMS2-like. (851 aa)
	LOC107582784	DNA mismatch repair protein Msh2-like. (946 aa)
	ENSSGRP00000098179	annotation not available (205 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000024222	ENSSGRP00000040788	ENSSGRP00000024222	ENSSGRP00000040788	mutL homolog 3 (E. coli).	annotation not available	0.935
ENSSGRP00000024222	ENSSGRP00000059625	ENSSGRP00000024222	ENSSGRP00000059625	mutL homolog 3 (E. coli).	annotation not available	0.935
ENSSGRP00000024222	LOC107550043	ENSSGRP00000024222	ENSSGRP00000041943	mutL homolog 3 (E. coli).	DNA mismatch repair protein Msh2-like.	0.935
ENSSGRP00000024222	LOC107582784	ENSSGRP00000024222	ENSSGRP00000087509	mutL homolog 3 (E. coli).	DNA mismatch repair protein Msh2-like.	0.935
ENSSGRP00000024222	LOC107588437	ENSSGRP00000024222	ENSSGRP00000042279	mutL homolog 3 (E. coli).	DNA mismatch repair protein Msh6-like isoform X1.	0.935
ENSSGRP00000024222	LOC107594169	ENSSGRP00000024222	ENSSGRP00000061177	mutL homolog 3 (E. coli).	Mismatch repair endonuclease PMS2-like.	0.673
ENSSGRP00000024222	PMS2	ENSSGRP00000024222	ENSSGRP00000014169	mutL homolog 3 (E. coli).	PMS1 homolog 2, mismatch repair system component.	0.673
ENSSGRP00000024222	mlh1	ENSSGRP00000024222	ENSSGRP00000059287	mutL homolog 3 (E. coli).	DNA mismatch repair protein MLH1.	0.996
ENSSGRP00000024222	msh3	ENSSGRP00000024222	ENSSGRP00000036773	mutL homolog 3 (E. coli).	DNA mismatch repair protein Msh3 isoform X1.	0.935
ENSSGRP00000040788	ENSSGRP00000024222	ENSSGRP00000040788	ENSSGRP00000024222	annotation not available	mutL homolog 3 (E. coli).	0.935
ENSSGRP00000040788	ENSSGRP00000059625	ENSSGRP00000040788	ENSSGRP00000059625	annotation not available	annotation not available	0.958
ENSSGRP00000040788	ENSSGRP00000098179	ENSSGRP00000040788	ENSSGRP00000098179	annotation not available	annotation not available	0.935
ENSSGRP00000040788	LOC107550043	ENSSGRP00000040788	ENSSGRP00000041943	annotation not available	DNA mismatch repair protein Msh2-like.	0.996
ENSSGRP00000040788	LOC107582784	ENSSGRP00000040788	ENSSGRP00000087509	annotation not available	DNA mismatch repair protein Msh2-like.	0.996
ENSSGRP00000040788	LOC107588437	ENSSGRP00000040788	ENSSGRP00000042279	annotation not available	DNA mismatch repair protein Msh6-like isoform X1.	0.958
ENSSGRP00000040788	LOC107594169	ENSSGRP00000040788	ENSSGRP00000061177	annotation not available	Mismatch repair endonuclease PMS2-like.	0.936
ENSSGRP00000040788	PMS2	ENSSGRP00000040788	ENSSGRP00000014169	annotation not available	PMS1 homolog 2, mismatch repair system component.	0.936
ENSSGRP00000040788	mlh1	ENSSGRP00000040788	ENSSGRP00000059287	annotation not available	DNA mismatch repair protein MLH1.	0.979
ENSSGRP00000059625	ENSSGRP00000024222	ENSSGRP00000059625	ENSSGRP00000024222	annotation not available	mutL homolog 3 (E. coli).	0.935
ENSSGRP00000059625	ENSSGRP00000040788	ENSSGRP00000059625	ENSSGRP00000040788	annotation not available	annotation not available	0.958