(76 nodes) Regulation of vasoconstriction network (Sinocyclocheilus grahami)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107584759	Bone morphogenetic protein receptor type-2-like. (1008 aa)
	LOC107552049	Histamine H2 receptor-like. (322 aa)
	HTR1A	5-hydroxytryptamine receptor 1A-alpha-like. (406 aa)
	bmpr2	Bone morphogenetic protein receptor type-2 isoform X1. (1064 aa)
	ENSSGRP00000107568	Endothelin-2-like. (169 aa)
	F2R-3	Coagulation factor II thrombin receptor. (393 aa)
	F2R-2	Coagulation factor II (thrombin) receptor. (405 aa)
	F2R	Coagulation factor II (thrombin) receptor. (402 aa)
	smtnl2	Smoothelin-like protein 2 isoform X1. (493 aa)
	ENSSGRP00000099098	Type-1A angiotensin II receptor-like. (371 aa)
	ENSSGRP00000099034	Type-1B angiotensin II receptor-like. (368 aa)
	LOC107591070	Arginine vasopressin receptor 2. (527 aa)
	ENSSGRP00000095779	Histamine receptor H2a. (338 aa)
	ENSSGRP00000095669	Dedicator of cytokinesis 4b. (1772 aa)
	ENSSGRP00000095282	Histamine receptor H2b. (303 aa)
	LOC107589255	5-hydroxytryptamine receptor 1A-beta-like. (413 aa)
	LOC107551767	Endothelin-1-like. (189 aa)
	ENSSGRP00000087881	Arginine vasopressin receptor 1A. (343 aa)
	ENSSGRP00000082150	annotation not available (457 aa)
	ENSSGRP00000080346	Endothelin-3-like. (176 aa)
	ENSSGRP00000080169	Adrenoceptor alpha 1Bb. (465 aa)
	LOC107552750	Alpha-1D adrenergic receptor-like. (491 aa)
	LOC107586059	Alpha-1A adrenergic receptor-like. (484 aa)
	LOC107590222	Arginine vasopressin receptor 2. (308 aa)
	ENSSGRP00000075503	Arginine vasopressin receptor 2. (372 aa)
	LOC107581260	Dedicator of cytokinesis protein 4-like. (1938 aa)
	ENSSGRP00000073860	5-hydroxytryptamine receptor 1A-alpha-like. (405 aa)
	LOC107550594	Type-1 angiotensin II receptor-like. (358 aa)
	LOC107552592	Adrenergic receptor alpha-2C. (432 aa)
	ENSSGRP00000071346	Isotocin receptor. (391 aa)
	LOC107594747	Endothelin-3-like. (153 aa)
	LOC107551532	Endothelin-3-like. (153 aa)
	LOC107593012	Bone morphogenetic protein receptor type-2-like. (1085 aa)
	LOC107565372	Adenosine receptor A2b-like isoform X1. (377 aa)
	LOC107562097	Thromboxane A2 receptor-like. (377 aa)
	ENSSGRP00000060606	annotation not available (352 aa)
	ENSSGRP00000060605	Coagulation factor II (thrombin) receptor. (402 aa)
	ENSSGRP00000060604	annotation not available (395 aa)
	ENSSGRP00000060602	Coagulation factor II (thrombin) receptor. (361 aa)
	LOC107585381	Proteinase-activated receptor 1-like isoform X1. (465 aa)
	LOC107553034	Alpha-1A adrenergic receptor-like. (486 aa)
	ENSSGRP00000056624	Arginine vasopressin receptor 1Aa. (336 aa)
	LOC107599421	Arginine vasopressin receptor 2. (369 aa)
	LOC107592260	Arginine vasopressin receptor 1A. (398 aa)
	ENSSGRP00000052435	Tachykinin-like peptides receptor 86C. (342 aa)
	LOC107588672	Arginine vasopressin receptor 2. (308 aa)
	LOC107560518	Alpha-1A adrenergic receptor-like. (438 aa)
	LOC107567044	Alpha-1D adrenergic receptor-like. (484 aa)
	LOC107552332	Histamine H2 receptor-like. (383 aa)
	ENSSGRP00000047882	Endothelin 2. (132 aa)
	LOC107591737	5-hydroxytryptamine receptor 1A-beta-like. (413 aa)
	ENSSGRP00000044098	Arginine vasopressin receptor 2a, duplicate b. (327 aa)
	ENSSGRP00000041684	Fibrinogen beta chain. (249 aa)
	LOC107555966	Isotocin receptor-like. (382 aa)
	ENSSGRP00000037916	annotation not available (162 aa)
	zdhhc21	Palmitoyltransferase ZDHHC21 isoform X1. (264 aa)
	LOC107555441	Bone morphogenetic protein receptor type-2-like isoform X1. (1018 aa)
	ENSSGRP00000030492	Adrenoceptor alpha 1Ab. (450 aa)
	LOC107590063	Alpha-2Db adrenergic receptor. (415 aa)
	LOC107559829	Thromboxane A2 receptor-like. (402 aa)
	ENSSGRP00000024962	Arginine vasopressin receptor 2a, duplicate b. (471 aa)
	ENSSGRP00000024678	Alpha-1A adrenergic receptor-like. (440 aa)
	ENSSGRP00000024648	Adrenoceptor alpha 1Aa. (486 aa)
	ENSSGRP00000024517	Alpha-2Db adrenergic receptor-like. (415 aa)
	ENSSGRP00000022668	Probable palmitoyltransferase ZDHHC21. (264 aa)
	AVPR1A	Arginine vasopressin receptor 1A. (387 aa)
	LOC107576085	Type-1 angiotensin II receptor A-like. (359 aa)
	ENSSGRP00000017156	P2X purinoceptor 1-like. (409 aa)
	LOC107564337	Fibrinogen beta chain-like isoform X1. (487 aa)
	LOC107556512	Alpha-2C adrenergic receptor-like. (432 aa)
	LOC107559691	Endothelin-1-like. (226 aa)
	ENSSGRP00000008564	annotation not available (334 aa)
	LOC107557561	Type-1 angiotensin II receptor A-like. (348 aa)
	LOC107577673	Isotocin receptor-like. (348 aa)
	ENSSGRP00000004146	Type-1A angiotensin II receptor-like. (290 aa)
	LOC107590113	Alpha-1A adrenergic receptor-like. (494 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AVPR1A	ENSSGRP00000037916	ENSSGRP00000020244	ENSSGRP00000037916	Arginine vasopressin receptor 1A.	annotation not available	0.515
AVPR1A	ENSSGRP00000047882	ENSSGRP00000020244	ENSSGRP00000047882	Arginine vasopressin receptor 1A.	Endothelin 2.	0.408
AVPR1A	ENSSGRP00000080346	ENSSGRP00000020244	ENSSGRP00000080346	Arginine vasopressin receptor 1A.	Endothelin-3-like.	0.515
AVPR1A	ENSSGRP00000087881	ENSSGRP00000020244	ENSSGRP00000087881	Arginine vasopressin receptor 1A.	Arginine vasopressin receptor 1A.	0.948
AVPR1A	ENSSGRP00000107568	ENSSGRP00000020244	ENSSGRP00000107568	Arginine vasopressin receptor 1A.	Endothelin-2-like.	0.408
AVPR1A	LOC107551532	ENSSGRP00000020244	ENSSGRP00000071145	Arginine vasopressin receptor 1A.	Endothelin-3-like.	0.515
AVPR1A	LOC107551767	ENSSGRP00000020244	ENSSGRP00000088481	Arginine vasopressin receptor 1A.	Endothelin-1-like.	0.621
AVPR1A	LOC107559691	ENSSGRP00000020244	ENSSGRP00000008726	Arginine vasopressin receptor 1A.	Endothelin-1-like.	0.621
AVPR1A	LOC107592260	ENSSGRP00000020244	ENSSGRP00000053502	Arginine vasopressin receptor 1A.	Arginine vasopressin receptor 1A.	0.957
AVPR1A	LOC107594747	ENSSGRP00000020244	ENSSGRP00000071339	Arginine vasopressin receptor 1A.	Endothelin-3-like.	0.515
ENSSGRP00000004146	ENSSGRP00000037916	ENSSGRP00000004146	ENSSGRP00000037916	Type-1A angiotensin II receptor-like.	annotation not available	0.653
ENSSGRP00000004146	ENSSGRP00000047882	ENSSGRP00000004146	ENSSGRP00000047882	Type-1A angiotensin II receptor-like.	Endothelin 2.	0.611
ENSSGRP00000004146	ENSSGRP00000080346	ENSSGRP00000004146	ENSSGRP00000080346	Type-1A angiotensin II receptor-like.	Endothelin-3-like.	0.653
ENSSGRP00000004146	ENSSGRP00000107568	ENSSGRP00000004146	ENSSGRP00000107568	Type-1A angiotensin II receptor-like.	Endothelin-2-like.	0.611
ENSSGRP00000004146	LOC107551532	ENSSGRP00000004146	ENSSGRP00000071145	Type-1A angiotensin II receptor-like.	Endothelin-3-like.	0.653
ENSSGRP00000004146	LOC107551767	ENSSGRP00000004146	ENSSGRP00000088481	Type-1A angiotensin II receptor-like.	Endothelin-1-like.	0.686
ENSSGRP00000004146	LOC107559691	ENSSGRP00000004146	ENSSGRP00000008726	Type-1A angiotensin II receptor-like.	Endothelin-1-like.	0.686
ENSSGRP00000004146	LOC107594747	ENSSGRP00000004146	ENSSGRP00000071339	Type-1A angiotensin II receptor-like.	Endothelin-3-like.	0.653
ENSSGRP00000008564	ENSSGRP00000037916	ENSSGRP00000008564	ENSSGRP00000037916	annotation not available	annotation not available	0.653
ENSSGRP00000008564	ENSSGRP00000047882	ENSSGRP00000008564	ENSSGRP00000047882	annotation not available	Endothelin 2.	0.611