(30 nodes) cGMP-mediated signaling network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107577312	Activity-dependent neuroprotector homeobox protein-like. (617 aa)
	ENSSGRP00000009221	Aquaporin-1-like. (279 aa)
	ENSSGRP00000104834	Aquaporin 1a (Colton blood group), tandem duplicate 1. (249 aa)
	ENSSGRP00000020485	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like. (527 aa)
	ENSSGRP00000022062	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like. (507 aa)
	Gucy1b3	Guanylate cyclase soluble subunit beta-1. (564 aa)
	ENSSGRP00000024308	Guanylate cyclase soluble subunit alpha-3-like. (676 aa)
	GUCY1A2	Guanylate cyclase 1 soluble subunit alpha 2. (711 aa)
	ENSSGRP00000031551	Activity-dependent neuroprotector homeobox b. (948 aa)
	ENSSGRP00000034747	Guanylate cyclase 1, soluble, beta 2. (315 aa)
	ENSSGRP00000035392	5-hydroxytryptamine receptor 2B-like. (433 aa)
	gucy1a2	Guanylate cyclase soluble subunit alpha-2. (743 aa)
	ENSSGRP00000046014	Cyclic GMP-AMP synthase-like. (376 aa)
	ENSSGRP00000059678	Guanylate cyclase soluble subunit beta-1-like. (223 aa)
	ENSSGRP00000060532	Guanylate cyclase soluble subunit beta-2-like. (143 aa)
	ENSSGRP00000060536	annotation not available (682 aa)
	ENSSGRP00000068949	Activity-dependent neuroprotector homeobox protein-like. (975 aa)
	ENSSGRP00000074526	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like. (256 aa)
	ENSSGRP00000081097	annotation not available (490 aa)
	ENSSGRP00000098335	5-hydroxytryptamine receptor 2B-like. (358 aa)
	ENSSGRP00000099199	Phosphodiesterase 9A like. (473 aa)
	LOC107567876	Aquaporin-1-like. (260 aa)
	ENSSGRP00000106516	annotation not available (510 aa)
	LOC107563106	Activity-dependent neuroprotector homeobox protein-like. (964 aa)
	LOC107581489	Guanylate cyclase soluble subunit beta-2-like. (755 aa)
	ENSSGRP00000112514	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like. (479 aa)
	LOC107572203	Guanylate cyclase soluble subunit alpha-3-like isoform X1. (687 aa)
	LOC107567874	Aquaporin-1-like. (269 aa)
	ENSSGRP00000011443	Cyclic GMP-AMP synthase-like isoform X1. (434 aa)
	ENSSGRP00000009878	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like. (199 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000009878	ENSSGRP00000024308	ENSSGRP00000009878	ENSSGRP00000024308	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-3-like.	0.776
ENSSGRP00000009878	ENSSGRP00000060532	ENSSGRP00000009878	ENSSGRP00000060532	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-2-like.	0.751
ENSSGRP00000009878	Gucy1b3	ENSSGRP00000009878	ENSSGRP00000024304	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-1.	0.750
ENSSGRP00000009878	LOC107572203	ENSSGRP00000009878	ENSSGRP00000069384	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-3-like isoform X1.	0.776
ENSSGRP00000009878	LOC107581489	ENSSGRP00000009878	ENSSGRP00000110830	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-2-like.	0.751
ENSSGRP00000009878	gucy1a2	ENSSGRP00000009878	ENSSGRP00000038016	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-2.	0.776
ENSSGRP00000011443	ENSSGRP00000046014	ENSSGRP00000011443	ENSSGRP00000046014	Cyclic GMP-AMP synthase-like isoform X1.	Cyclic GMP-AMP synthase-like.	0.900
ENSSGRP00000020485	ENSSGRP00000024308	ENSSGRP00000020485	ENSSGRP00000024308	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-3-like.	0.769
ENSSGRP00000020485	ENSSGRP00000060532	ENSSGRP00000020485	ENSSGRP00000060532	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-2-like.	0.751
ENSSGRP00000020485	Gucy1b3	ENSSGRP00000020485	ENSSGRP00000024304	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-1.	0.750
ENSSGRP00000020485	LOC107572203	ENSSGRP00000020485	ENSSGRP00000069384	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-3-like isoform X1.	0.769
ENSSGRP00000020485	LOC107581489	ENSSGRP00000020485	ENSSGRP00000110830	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-2-like.	0.751
ENSSGRP00000020485	gucy1a2	ENSSGRP00000020485	ENSSGRP00000038016	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-2.	0.769
ENSSGRP00000022062	ENSSGRP00000024308	ENSSGRP00000022062	ENSSGRP00000024308	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-3-like.	0.769
ENSSGRP00000022062	ENSSGRP00000060532	ENSSGRP00000022062	ENSSGRP00000060532	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-2-like.	0.751
ENSSGRP00000022062	Gucy1b3	ENSSGRP00000022062	ENSSGRP00000024304	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-1.	0.750
ENSSGRP00000022062	LOC107572203	ENSSGRP00000022062	ENSSGRP00000069384	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-3-like isoform X1.	0.769
ENSSGRP00000022062	LOC107581489	ENSSGRP00000022062	ENSSGRP00000110830	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit beta-2-like.	0.751
ENSSGRP00000022062	gucy1a2	ENSSGRP00000022062	ENSSGRP00000038016	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	Guanylate cyclase soluble subunit alpha-2.	0.769
ENSSGRP00000024308	ENSSGRP00000009878	ENSSGRP00000024308	ENSSGRP00000009878	Guanylate cyclase soluble subunit alpha-3-like.	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like.	0.776