(44 nodes) Protein tyrosine kinase activator activity network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000044362	annotation not available (62 aa)
	ENSSGRP00000040670	Neuregulin 2b. (571 aa)
	ENSSGRP00000033547	annotation not available (62 aa)
	LOC107582823	Ghrelin-like. (101 aa)
	ENSSGRP00000029530	annotation not available (90 aa)
	ENSSGRP00000025093	Protein FAM150-like. (151 aa)
	LOC107557065	Proheparin-binding EGF-like growth factor. (222 aa)
	LOC107564117	Pro-neuregulin-1, membrane-bound isoform-like. (691 aa)
	LOC107557058	Pro-neuregulin-2, membrane-bound isoform-like isoform X1. (803 aa)
	Pak2	Serine/threonine-protein kinase PAK 2. (471 aa)
	ENSSGRP00000009501	annotation not available (87 aa)
	LOC107575152	Pro-neuregulin-1, membrane-bound isoform-like isoform X1. (683 aa)
	ENSSGRP00000007826	Growth arrest-specific protein 6-like. (598 aa)
	ENSSGRP00000004635	annotation not available (124 aa)
	ENSSGRP00000003305	Abl interactor 1-like. (104 aa)
	ENSSGRP00000002570	Proheparin-binding EGF-like growth factor. (209 aa)
	ENSSGRP00000044940	Gremlin-1-like. (168 aa)
	GREM1	Gremlin-1-like. (177 aa)
	ENSSGRP00000054531	Probetacellulin-like isoform X1. (168 aa)
	Abi1	Abl interactor 1 isoform X1. (542 aa)
	ENSSGRP00000058664	annotation not available (875 aa)
	LOC107591323	Serine/threonine-protein kinase PAK 2-like. (515 aa)
	LOC107559371	Abl interactor 1-like isoform X1. (507 aa)
	LOC107565989	Epigen-like isoform X1. (155 aa)
	ENSSGRP00000108642	Abl interactor 1-like isoform X1. (472 aa)
	ENSSGRP00000102630	Ghrelin. (109 aa)
	ENSSGRP00000089852	annotation not available (119 aa)
	ENSSGRP00000089850	annotation not available (238 aa)
	GREM1-2	Gremlin-1-like. (174 aa)
	alkal2	Protein FAM150B. (147 aa)
	ENSSGRP00000086323	ALK and LTK ligand 2b. (210 aa)
	ENSSGRP00000082393	Gremlin 2, DAN family BMP antagonist a. (151 aa)
	LOC107587125	Proheparin-binding EGF-like growth factor. (228 aa)
	LOC107583498	Gremlin-2-like. (194 aa)
	ENSSGRP00000072183	Epigen-like isoform X1. (142 aa)
	ENSSGRP00000064700	Serine/threonine-protein kinase PAK 2-like. (516 aa)
	DGKQ	Diacylglycerol kinase theta. (841 aa)
	LOC107588615	DNA excision repair protein ERCC-6-like. (1395 aa)
	LOC107557297	Serine/threonine-protein kinase PAK 2-like. (518 aa)
	ENSSGRP00000070407	Pro-neuregulin-2, membrane-bound isoform-like. (701 aa)
	ENSSGRP00000070509	Pro-neuregulin-2, membrane-bound isoform-like isoform X1. (568 aa)
	ENSSGRP00000048607	Growth arrest-specific protein 6-like. (105 aa)
	ENSSGRP00000048601	Growth arrest-specific 6. (396 aa)
	LOC107559299	Proheparin-binding EGF-like growth factor. (222 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abi1	ENSSGRP00000064700	ENSSGRP00000054561	ENSSGRP00000064700	Abl interactor 1 isoform X1.	Serine/threonine-protein kinase PAK 2-like.	0.422
Abi1	LOC107557297	ENSSGRP00000054561	ENSSGRP00000070239	Abl interactor 1 isoform X1.	Serine/threonine-protein kinase PAK 2-like.	0.422
Abi1	LOC107591323	ENSSGRP00000054561	ENSSGRP00000061968	Abl interactor 1 isoform X1.	Serine/threonine-protein kinase PAK 2-like.	0.422
Abi1	Pak2	ENSSGRP00000054561	ENSSGRP00000021375	Abl interactor 1 isoform X1.	Serine/threonine-protein kinase PAK 2.	0.422
ENSSGRP00000002570	ENSSGRP00000004635	ENSSGRP00000002570	ENSSGRP00000004635	Proheparin-binding EGF-like growth factor.	annotation not available	0.720
ENSSGRP00000002570	ENSSGRP00000040670	ENSSGRP00000002570	ENSSGRP00000040670	Proheparin-binding EGF-like growth factor.	Neuregulin 2b.	0.427
ENSSGRP00000002570	ENSSGRP00000054531	ENSSGRP00000002570	ENSSGRP00000054531	Proheparin-binding EGF-like growth factor.	Probetacellulin-like isoform X1.	0.720
ENSSGRP00000002570	ENSSGRP00000070407	ENSSGRP00000002570	ENSSGRP00000070407	Proheparin-binding EGF-like growth factor.	Pro-neuregulin-2, membrane-bound isoform-like.	0.427
ENSSGRP00000002570	ENSSGRP00000070509	ENSSGRP00000002570	ENSSGRP00000070509	Proheparin-binding EGF-like growth factor.	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	0.431
ENSSGRP00000002570	ENSSGRP00000072183	ENSSGRP00000002570	ENSSGRP00000072183	Proheparin-binding EGF-like growth factor.	Epigen-like isoform X1.	0.679
ENSSGRP00000002570	LOC107557058	ENSSGRP00000002570	ENSSGRP00000024060	Proheparin-binding EGF-like growth factor.	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	0.431
ENSSGRP00000002570	LOC107564117	ENSSGRP00000002570	ENSSGRP00000024285	Proheparin-binding EGF-like growth factor.	Pro-neuregulin-1, membrane-bound isoform-like.	0.427
ENSSGRP00000002570	LOC107565989	ENSSGRP00000002570	ENSSGRP00000111764	Proheparin-binding EGF-like growth factor.	Epigen-like isoform X1.	0.679
ENSSGRP00000002570	LOC107575152	ENSSGRP00000002570	ENSSGRP00000008698	Proheparin-binding EGF-like growth factor.	Pro-neuregulin-1, membrane-bound isoform-like isoform X1.	0.427
ENSSGRP00000003305	ENSSGRP00000064700	ENSSGRP00000003305	ENSSGRP00000064700	Abl interactor 1-like.	Serine/threonine-protein kinase PAK 2-like.	0.422
ENSSGRP00000003305	LOC107557297	ENSSGRP00000003305	ENSSGRP00000070239	Abl interactor 1-like.	Serine/threonine-protein kinase PAK 2-like.	0.422
ENSSGRP00000003305	LOC107591323	ENSSGRP00000003305	ENSSGRP00000061968	Abl interactor 1-like.	Serine/threonine-protein kinase PAK 2-like.	0.422
ENSSGRP00000003305	Pak2	ENSSGRP00000003305	ENSSGRP00000021375	Abl interactor 1-like.	Serine/threonine-protein kinase PAK 2.	0.422
ENSSGRP00000004635	ENSSGRP00000002570	ENSSGRP00000004635	ENSSGRP00000002570	annotation not available	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000004635	ENSSGRP00000040670	ENSSGRP00000004635	ENSSGRP00000040670	annotation not available	Neuregulin 2b.	0.561