(100 nodes) Negative regulation of axon extension network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000018097	annotation not available (576 aa)
	ENSSGRP00000017785	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba. (722 aa)
	LOC107599253	Semaphorin-4E-like. (757 aa)
	ENSSGRP00000016927	Disco-interacting protein 2 homolog B-A isoform X1. (1584 aa)
	LOC107575741	semaphorin-3F-like. (806 aa)
	LOC107560735	Semaphorin-3aa-like. (866 aa)
	tnr	Tenascin-R isoform X1. (1364 aa)
	ENSSGRP00000013338	Si:ch211-113g11.6. (562 aa)
	LOC107587820	Semaphorin-6D-like isoform X1. (1069 aa)
	LOC107585743	Ephrin type-A receptor 4-like. (988 aa)
	IFRD1	Interferon-related developmental regulator 1-like isoform X1. (429 aa)
	LOC107556493	Interferon-related developmental regulator 2-like isoform X1. (455 aa)
	ENSSGRP00000009213	Semaphorin-4E-like. (517 aa)
	LOC107583108	Ephrin type-A receptor 4-like isoform X1. (995 aa)
	ENSSGRP00000007595	Reticulon-4 receptor-like. (456 aa)
	ENSSGRP00000007594	Reticulon-4 receptor-like. (419 aa)
	ENSSGRP00000007388	Semaphorin-4G-like. (809 aa)
	Sema3g	Semaphorin-3G isoform X1. (747 aa)
	ENSSGRP00000005948	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B. (778 aa)
	ENSSGRP00000005585	annotation not available (256 aa)
	LOC107593332	Semaphorin-4E-like. (796 aa)
	ENSSGRP00000001478	Semaphorin-3F-like isoform X1. (786 aa)
	LOC107562295	Semaphorin-3aa. (874 aa)
	ENSSGRP00000110357	Disco-interacting protein 2 homolog C-like. (1234 aa)
	SEMA4F	Semaphorin-4F-like isoform X1. (801 aa)
	ENSSGRP00000032915	Disco-interacting protein 2 homolog Ca. (1562 aa)
	ENSSGRP00000033077	annotation not available (594 aa)
	ENSSGRP00000035593	annotation not available (853 aa)
	ENSSGRP00000036623	Semaphorin 7A. (387 aa)
	LOC107588527	Semaphorin-6D-like isoform X1. (1076 aa)
	ENSSGRP00000038500	Receptor like tyrosine kinase. (595 aa)
	ENSSGRP00000041816	Semaphorin-5B-like. (1013 aa)
	SEMA4D	Semaphorin-4D-like. (872 aa)
	ENSSGRP00000043383	annotation not available (114 aa)
	ENSSGRP00000043386	annotation not available (113 aa)
	LOC107565799	Semaphorin-4G-like. (884 aa)
	ENSSGRP00000048297	Disco-interacting protein 2 homolog C-like. (1467 aa)
	ENSSGRP00000048514	Ephrin type-A receptor 4-like. (986 aa)
	ENSSGRP00000051265	Semaphorin-6D-like. (877 aa)
	ENSSGRP00000053071	annotation not available (1016 aa)
	ENSSGRP00000054507	Disco-interacting protein 2 homolog B-A-like isoform X1. (1587 aa)
	ENSSGRP00000054638	Disco-interacting protein 2 homolog Cb. (1343 aa)
	LOC107584390	Wingless-type MMTV integration site family, member 3. (355 aa)
	ENSSGRP00000056521	Disco-interacting protein 2 homolog Bb. (1392 aa)
	LOC107591772	Semaphorin-3B-like. (779 aa)
	ENSSGRP00000058740	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl. (742 aa)
	ENSSGRP00000058767	Interferon-related developmental regulator 2-like isoform X1. (434 aa)
	LOC107586415	Semaphorin-4E-like isoform X1. (816 aa)
	ENSSGRP00000063437	annotation not available (728 aa)
	LOC107558359	tenascin-R-like. (1323 aa)
	ENSSGRP00000064239	annotation not available (783 aa)
	LOC107585981	Semaphorin-4B-like. (848 aa)
	ENSSGRP00000067010	Semaphorin-6D-like. (824 aa)
	ENSSGRP00000067431	Semaphorin-5A-like. (1045 aa)
	ENSSGRP00000073081	Semaphorin-5B-like. (1062 aa)
	ENSSGRP00000074461	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa. (753 aa)
	LOC107580056	Interferon-related developmental regulator 1-like isoform X1. (436 aa)
	ENSSGRP00000077635	LOW QUALITY PROTEIN: semaphorin-5B-like. (1013 aa)
	ENSSGRP00000081076	Reticulon 4 receptor. (404 aa)
	ENSSGRP00000083615	Fibroblast growth factor receptor 3-like. (414 aa)
	ENSSGRP00000085495	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C. (744 aa)
	ENSSGRP00000086545	Disco-interacting protein 2 homolog A-like. (1487 aa)
	ENSSGRP00000086661	Semaphorin-7A-like. (402 aa)
	Sema3c	Semaphorin-3C. (766 aa)
	LOC107557846	Semaphorin-6D-like isoform X1. (1080 aa)
	ENSSGRP00000090666	annotation not available (789 aa)
	LOC107597982	Semaphorin-7A-like. (633 aa)
	LOC107597993	Semaphorin-6D-like isoform X1. (1070 aa)
	LOC107556264	Semaphorin-4B-like. (831 aa)
	ENSSGRP00000093959	Disco-interacting protein 2 homolog Ca. (1624 aa)
	ENSSGRP00000094068	Semaphorin-4B-like. (524 aa)
	ENSSGRP00000094364	Semaphorin-4D-like isoform X1. (887 aa)
	LOC107582524	Semaphorin-4G-like. (867 aa)
	ENSSGRP00000096489	Semaphorin-3D-like. (291 aa)
	ENSSGRP00000096493	Si:dkey-49n23.1. (374 aa)
	LOC107558010	Wingless-type MMTV integration site family, member 3. (353 aa)
	ENSSGRP00000096946	Semaphorin-7A-like. (364 aa)
	sema4c	Semaphorin-4C isoform X1. (865 aa)
	LOC107561807	Ephrin type-A receptor 4. (963 aa)
	ENSSGRP00000100916	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D. (291 aa)
	ENSSGRP00000100921	Semaphorin-3D-like. (533 aa)
	ENSSGRP00000101147	Semaphorin-3ab. (778 aa)
	ENSSGRP00000101185	annotation not available (574 aa)
	LOC107563409	Semaphorin-3E-like isoform X1. (785 aa)
	ENSSGRP00000105155	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba. (809 aa)
	ENSSGRP00000106114	Receptor like tyrosine kinase. (583 aa)
	ENSSGRP00000106892	Disco-interacting protein 2 homolog B-A-like. (1336 aa)
	wnt3a	Wnt family member 3A. (369 aa)
	ENSSGRP00000030820	annotation not available (879 aa)
	LOC107552650	Semaphorin-3F-like. (767 aa)
	LOC107559401	Semaphorin-3D isoform X1. (767 aa)
	LOC107556586	Wingless-type MMTV integration site family, member 3. (355 aa)
	ENSSGRP00000029778	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab. (730 aa)
	LOC107559846	Semaphorin-3E-like. (781 aa)
	ENSSGRP00000025869	Cyclin-dependent kinase 5. (281 aa)
	LOC107593030	Semaphorin-4B-like. (848 aa)
	ENSSGRP00000025260	Semaphorin-6B-like. (716 aa)
	LOC107569067	Semaphorin-4F-like isoform X1. (803 aa)
	ENSSGRP00000018689	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb. (816 aa)
	ENSSGRP00000018649	Semaphorin-5B-like isoform X1. (915 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000001478	ENSSGRP00000025869	ENSSGRP00000001478	ENSSGRP00000025869	Semaphorin-3F-like isoform X1.	Cyclin-dependent kinase 5.	0.434
ENSSGRP00000005948	ENSSGRP00000025869	ENSSGRP00000005948	ENSSGRP00000025869	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B.	Cyclin-dependent kinase 5.	0.711
ENSSGRP00000007388	ENSSGRP00000025869	ENSSGRP00000007388	ENSSGRP00000025869	Semaphorin-4G-like.	Cyclin-dependent kinase 5.	0.524
ENSSGRP00000009213	ENSSGRP00000025869	ENSSGRP00000009213	ENSSGRP00000025869	Semaphorin-4E-like.	Cyclin-dependent kinase 5.	0.434
ENSSGRP00000013338	ENSSGRP00000025869	ENSSGRP00000013338	ENSSGRP00000025869	Si:ch211-113g11.6.	Cyclin-dependent kinase 5.	0.434
ENSSGRP00000017785	ENSSGRP00000025869	ENSSGRP00000017785	ENSSGRP00000025869	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba.	Cyclin-dependent kinase 5.	0.524
ENSSGRP00000018097	ENSSGRP00000025869	ENSSGRP00000018097	ENSSGRP00000025869	annotation not available	Cyclin-dependent kinase 5.	0.524
ENSSGRP00000018649	ENSSGRP00000025869	ENSSGRP00000018649	ENSSGRP00000025869	Semaphorin-5B-like isoform X1.	Cyclin-dependent kinase 5.	0.524
ENSSGRP00000018689	ENSSGRP00000025869	ENSSGRP00000018689	ENSSGRP00000025869	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb.	Cyclin-dependent kinase 5.	0.524
ENSSGRP00000025260	ENSSGRP00000025869	ENSSGRP00000025260	ENSSGRP00000025869	Semaphorin-6B-like.	Cyclin-dependent kinase 5.	0.524
ENSSGRP00000025869	ENSSGRP00000001478	ENSSGRP00000025869	ENSSGRP00000001478	Cyclin-dependent kinase 5.	Semaphorin-3F-like isoform X1.	0.434
ENSSGRP00000025869	ENSSGRP00000005948	ENSSGRP00000025869	ENSSGRP00000005948	Cyclin-dependent kinase 5.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B.	0.711
ENSSGRP00000025869	ENSSGRP00000007388	ENSSGRP00000025869	ENSSGRP00000007388	Cyclin-dependent kinase 5.	Semaphorin-4G-like.	0.524
ENSSGRP00000025869	ENSSGRP00000009213	ENSSGRP00000025869	ENSSGRP00000009213	Cyclin-dependent kinase 5.	Semaphorin-4E-like.	0.434
ENSSGRP00000025869	ENSSGRP00000013338	ENSSGRP00000025869	ENSSGRP00000013338	Cyclin-dependent kinase 5.	Si:ch211-113g11.6.	0.434
ENSSGRP00000025869	ENSSGRP00000017785	ENSSGRP00000025869	ENSSGRP00000017785	Cyclin-dependent kinase 5.	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba.	0.524
ENSSGRP00000025869	ENSSGRP00000018097	ENSSGRP00000025869	ENSSGRP00000018097	Cyclin-dependent kinase 5.	annotation not available	0.524
ENSSGRP00000025869	ENSSGRP00000018649	ENSSGRP00000025869	ENSSGRP00000018649	Cyclin-dependent kinase 5.	Semaphorin-5B-like isoform X1.	0.524
ENSSGRP00000025869	ENSSGRP00000018689	ENSSGRP00000025869	ENSSGRP00000018689	Cyclin-dependent kinase 5.	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb.	0.524
ENSSGRP00000025869	ENSSGRP00000025260	ENSSGRP00000025869	ENSSGRP00000025260	Cyclin-dependent kinase 5.	Semaphorin-6B-like.	0.524