(25 nodes) Response to fluid shear stress network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000070226	Mothers against decapentaplegic homolog 6-like isoform X1. (454 aa)
	ENSSGRP00000003337	Nuclear factor erythroid 2-related factor 2-like. (146 aa)
	smad6	Mothers against decapentaplegic homolog 6. (450 aa)
	ENSSGRP00000007656	Nuclear factor erythroid 2-related factor 2-like. (306 aa)
	ENSSGRP00000007885	UbiA prenyltransferase domain containing 1. (334 aa)
	LOC107575167	UbiA prenyltransferase domain-containing protein 1-like. (343 aa)
	LOC107594434	Polycystin-2-like isoform X1. (904 aa)
	LOC107583176	Polycystin-2-like isoform X1. (900 aa)
	ENSSGRP00000029944	Polycystic kidney disease 1b. (3037 aa)
	ENSSGRP00000049040	Polycystic kidney disease 1a. (4395 aa)
	LOC107583766	Mothers against decapentaplegic homolog 6-like. (487 aa)
	Smad7	Mothers against decapentaplegic homolog 7. (182 aa)
	LOC107596967	Mothers against decapentaplegic homolog 6-like. (488 aa)
	LOC107589869	Prostaglandin-endoperoxide synthase 2. (607 aa)
	ENSSGRP00000103385	X-box binding protein 1. (381 aa)
	LOC107600008	P2X purinoceptor 4-like. (596 aa)
	LOC107585655	Mothers against decapentaplegic homolog 7-like. (371 aa)
	LOC107553505	Prostaglandin-endoperoxide synthase 2. (615 aa)
	ENSSGRP00000084589	P2X purinoceptor 4-like isoform X1. (579 aa)
	Pkd1	Polycystin 1. (4499 aa)
	LOC107600731	Nuclear factor erythroid 2-related factor 2-like. (473 aa)
	LOC107594645	Prostaglandin-endoperoxide synthase 2. (605 aa)
	LOC107584772	Nuclear factor erythroid 2-related factor 2-like isoform X1. (540 aa)
	ENSSGRP00000054888	annotation not available (348 aa)
	ENSSGRP00000072936	Prostaglandin-endoperoxide synthase 2. (561 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000029944	LOC107583176	ENSSGRP00000029944	ENSSGRP00000020709	Polycystic kidney disease 1b.	Polycystin-2-like isoform X1.	0.934
ENSSGRP00000029944	LOC107594434	ENSSGRP00000029944	ENSSGRP00000013602	Polycystic kidney disease 1b.	Polycystin-2-like isoform X1.	0.934
ENSSGRP00000049040	LOC107583176	ENSSGRP00000049040	ENSSGRP00000020709	Polycystic kidney disease 1a.	Polycystin-2-like isoform X1.	0.904
ENSSGRP00000049040	LOC107594434	ENSSGRP00000049040	ENSSGRP00000013602	Polycystic kidney disease 1a.	Polycystin-2-like isoform X1.	0.904
ENSSGRP00000084589	LOC107600008	ENSSGRP00000084589	ENSSGRP00000095911	P2X purinoceptor 4-like isoform X1.	P2X purinoceptor 4-like.	0.900
LOC107583176	ENSSGRP00000029944	ENSSGRP00000020709	ENSSGRP00000029944	Polycystin-2-like isoform X1.	Polycystic kidney disease 1b.	0.934
LOC107583176	ENSSGRP00000049040	ENSSGRP00000020709	ENSSGRP00000049040	Polycystin-2-like isoform X1.	Polycystic kidney disease 1a.	0.904
LOC107583176	Pkd1	ENSSGRP00000020709	ENSSGRP00000083216	Polycystin-2-like isoform X1.	Polycystin 1.	0.904
LOC107594434	ENSSGRP00000029944	ENSSGRP00000013602	ENSSGRP00000029944	Polycystin-2-like isoform X1.	Polycystic kidney disease 1b.	0.934
LOC107594434	ENSSGRP00000049040	ENSSGRP00000013602	ENSSGRP00000049040	Polycystin-2-like isoform X1.	Polycystic kidney disease 1a.	0.904
LOC107594434	Pkd1	ENSSGRP00000013602	ENSSGRP00000083216	Polycystin-2-like isoform X1.	Polycystin 1.	0.904
LOC107600008	ENSSGRP00000084589	ENSSGRP00000095911	ENSSGRP00000084589	P2X purinoceptor 4-like.	P2X purinoceptor 4-like isoform X1.	0.900
Pkd1	LOC107583176	ENSSGRP00000083216	ENSSGRP00000020709	Polycystin 1.	Polycystin-2-like isoform X1.	0.904
Pkd1	LOC107594434	ENSSGRP00000083216	ENSSGRP00000013602	Polycystin 1.	Polycystin-2-like isoform X1.	0.904