(33 nodes) Hippo signaling network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000015188	annotation not available (335 aa)
	ENSSGRP00000002353	annotation not available (309 aa)
	ENSSGRP00000005478	Praja ring finger ubiquitin ligase 2. (597 aa)
	ENSSGRP00000005670	Transcriptional enhancer factor TEF-5-like isoform X1. (394 aa)
	LOC107553191	Protein salvador homolog 1-like. (395 aa)
	ENSSGRP00000012494	MOB kinase activator 1Bb. (223 aa)
	ENSSGRP00000013771	WW domain containing transcription regulator 1. (401 aa)
	ENSSGRP00000026439	TEA domain family member 1b. (355 aa)
	ENSSGRP00000027460	Protocadherin Fat 4-like. (4859 aa)
	ENSSGRP00000027465	annotation not available (154 aa)
	LATS1	Serine/threonine-protein kinase LATS1-like. (1106 aa)
	ENSSGRP00000044184	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like. (1060 aa)
	Yap1	Transcriptional coactivator YAP1. (424 aa)
	ENSSGRP00000045748	TEA domain family member 3 b. (432 aa)
	ENSSGRP00000046761	annotation not available (76 aa)
	LOC107602931	Protein salvador homolog 1-like. (395 aa)
	ENSSGRP00000047105	annotation not available (382 aa)
	ENSSGRP00000056682	TEA domain family member 1b. (388 aa)
	ENSSGRP00000059309	WW domain containing transcription regulator 1. (378 aa)
	LOC107585392	MOB kinase activator 1B-like isoform X1. (216 aa)
	ENSSGRP00000071677	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS2-like. (1067 aa)
	ENSSGRP00000072136	Protocadherin Fat 4-like. (717 aa)
	LOC107572507	Transcriptional enhancer factor TEF-1. (422 aa)
	ENSSGRP00000072680	MOB kinase activator 1A-like isoform X1. (209 aa)
	ENSSGRP00000075046	annotation not available (4310 aa)
	LOC107553598	MOB kinase activator 1B-like. (216 aa)
	ENSSGRP00000097950	Transcriptional enhancer factor TEF-5-like. (460 aa)
	ENSSGRP00000098966	TEA domain family member 3 b. (403 aa)
	LOC107556381	Serine/threonine-protein kinase 3 isoform X1. (492 aa)
	LOC107569193	Serine/threonine-protein kinase LATS2-like. (1138 aa)
	ENSSGRP00000105755	Transcriptional coactivator YAP1-like. (369 aa)
	LOC107575311	Transcriptional enhancer factor TEF-1-like. (422 aa)
	LOC107552572	MOB kinase activator 1B. (216 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000002353	ENSSGRP00000012494	ENSSGRP00000002353	ENSSGRP00000012494	annotation not available	MOB kinase activator 1Bb.	0.973
ENSSGRP00000002353	ENSSGRP00000013771	ENSSGRP00000002353	ENSSGRP00000013771	annotation not available	WW domain containing transcription regulator 1.	0.930
ENSSGRP00000002353	ENSSGRP00000044184	ENSSGRP00000002353	ENSSGRP00000044184	annotation not available	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS1-like.	0.933
ENSSGRP00000002353	ENSSGRP00000046761	ENSSGRP00000002353	ENSSGRP00000046761	annotation not available	annotation not available	0.981
ENSSGRP00000002353	ENSSGRP00000059309	ENSSGRP00000002353	ENSSGRP00000059309	annotation not available	WW domain containing transcription regulator 1.	0.930
ENSSGRP00000002353	ENSSGRP00000071677	ENSSGRP00000002353	ENSSGRP00000071677	annotation not available	LOW QUALITY PROTEIN: serine/threonine-protein kinase LATS2-like.	0.933
ENSSGRP00000002353	ENSSGRP00000072680	ENSSGRP00000002353	ENSSGRP00000072680	annotation not available	MOB kinase activator 1A-like isoform X1.	0.973
ENSSGRP00000002353	ENSSGRP00000105755	ENSSGRP00000002353	ENSSGRP00000105755	annotation not available	Transcriptional coactivator YAP1-like.	0.930
ENSSGRP00000002353	LATS1	ENSSGRP00000002353	ENSSGRP00000030552	annotation not available	Serine/threonine-protein kinase LATS1-like.	0.933
ENSSGRP00000002353	LOC107552572	ENSSGRP00000002353	ENSSGRP00000106170	annotation not available	MOB kinase activator 1B.	0.821
ENSSGRP00000002353	LOC107553191	ENSSGRP00000002353	ENSSGRP00000007232	annotation not available	Protein salvador homolog 1-like.	0.981
ENSSGRP00000002353	LOC107553598	ENSSGRP00000002353	ENSSGRP00000089688	annotation not available	MOB kinase activator 1B-like.	0.821
ENSSGRP00000002353	LOC107569193	ENSSGRP00000002353	ENSSGRP00000101253	annotation not available	Serine/threonine-protein kinase LATS2-like.	0.933
ENSSGRP00000002353	LOC107585392	ENSSGRP00000002353	ENSSGRP00000065245	annotation not available	MOB kinase activator 1B-like isoform X1.	0.973
ENSSGRP00000002353	LOC107602931	ENSSGRP00000002353	ENSSGRP00000046762	annotation not available	Protein salvador homolog 1-like.	0.981
ENSSGRP00000002353	Yap1	ENSSGRP00000002353	ENSSGRP00000044525	annotation not available	Transcriptional coactivator YAP1.	0.930
ENSSGRP00000005670	ENSSGRP00000013771	ENSSGRP00000005670	ENSSGRP00000013771	Transcriptional enhancer factor TEF-5-like isoform X1.	WW domain containing transcription regulator 1.	0.837
ENSSGRP00000005670	ENSSGRP00000059309	ENSSGRP00000005670	ENSSGRP00000059309	Transcriptional enhancer factor TEF-5-like isoform X1.	WW domain containing transcription regulator 1.	0.837
ENSSGRP00000005670	ENSSGRP00000105755	ENSSGRP00000005670	ENSSGRP00000105755	Transcriptional enhancer factor TEF-5-like isoform X1.	Transcriptional coactivator YAP1-like.	0.895
ENSSGRP00000005670	Yap1	ENSSGRP00000005670	ENSSGRP00000044525	Transcriptional enhancer factor TEF-5-like isoform X1.	Transcriptional coactivator YAP1.	0.895