(27 nodes) Macrophage activation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000055921	N-myc-interactor-like. (300 aa)
	ENSSGRP00000002233	Group 10 secretory phospholipase A2-like. (144 aa)
	LOC107576986	Toll-like receptor 4. (550 aa)
	ENSSGRP00000006394	annotation not available (243 aa)
	ENSSGRP00000006528	Transcription factor AP-1-like. (305 aa)
	ENSSGRP00000012381	annotation not available (545 aa)
	ENSSGRP00000018523	Interferon-induced 35 kDa protein-like. (238 aa)
	LOC107551164	Interferon-induced 35 kDa protein homolog. (368 aa)
	LOC107561363	Interferon-induced 35 kDa protein homolog isoform X1. (368 aa)
	LOC107551613	Complement C1q subcomponent subunit A-like. (246 aa)
	LOC107582292	Lymphotoxin alpha (TNF superfamily, member 1). (244 aa)
	l3hypdh	Trans-3-hydroxy-L-proline dehydratase isoform X1. (345 aa)
	LOC107564700	Group 10 secretory phospholipase A2-like. (157 aa)
	LOC107598452	C-X-C chemokine receptor type 3-like. (381 aa)
	LOC107551671	C-X-C chemokine receptor type 3-like. (382 aa)
	ENSSGRP00000067469	Adhesion G protein-coupled receptor F5-like. (362 aa)
	LOC107563389	Transcription factor AP-1-like isoform X1. (323 aa)
	ENSSGRP00000079641	annotation not available (114 aa)
	LOC107596230	TYRO protein tyrosine kinase-binding protein-like. (116 aa)
	ENSSGRP00000069817	Transcription factor AP-1-like. (311 aa)
	ENSSGRP00000098252	TYRO protein tyrosine kinase binding protein. (110 aa)
	LOC107548128	Complement C1q subcomponent subunit A-like. (245 aa)
	ENSSGRP00000096223	Toll-like receptor 4. (760 aa)
	ENSSGRP00000090494	Toll-like receptor 4b, duplicate b. (673 aa)
	ENSSGRP00000090492	annotation not available (83 aa)
	ENSSGRP00000089497	annotation not available (104 aa)
	ENSSGRP00000089495	annotation not available (132 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000006394	ENSSGRP00000006528	ENSSGRP00000006394	ENSSGRP00000006528	annotation not available	Transcription factor AP-1-like.	0.507
ENSSGRP00000006394	ENSSGRP00000012381	ENSSGRP00000006394	ENSSGRP00000012381	annotation not available	annotation not available	0.496
ENSSGRP00000006394	ENSSGRP00000069817	ENSSGRP00000006394	ENSSGRP00000069817	annotation not available	Transcription factor AP-1-like.	0.507
ENSSGRP00000006394	ENSSGRP00000089495	ENSSGRP00000006394	ENSSGRP00000089495	annotation not available	annotation not available	0.499
ENSSGRP00000006394	ENSSGRP00000089497	ENSSGRP00000006394	ENSSGRP00000089497	annotation not available	annotation not available	0.499
ENSSGRP00000006394	ENSSGRP00000090492	ENSSGRP00000006394	ENSSGRP00000090492	annotation not available	annotation not available	0.509
ENSSGRP00000006394	ENSSGRP00000090494	ENSSGRP00000006394	ENSSGRP00000090494	annotation not available	Toll-like receptor 4b, duplicate b.	0.509
ENSSGRP00000006394	ENSSGRP00000096223	ENSSGRP00000006394	ENSSGRP00000096223	annotation not available	Toll-like receptor 4.	0.496
ENSSGRP00000006394	LOC107563389	ENSSGRP00000006394	ENSSGRP00000088629	annotation not available	Transcription factor AP-1-like isoform X1.	0.507
ENSSGRP00000006394	LOC107576986	ENSSGRP00000006394	ENSSGRP00000002901	annotation not available	Toll-like receptor 4.	0.496
ENSSGRP00000006528	ENSSGRP00000006394	ENSSGRP00000006528	ENSSGRP00000006394	Transcription factor AP-1-like.	annotation not available	0.507
ENSSGRP00000006528	ENSSGRP00000069817	ENSSGRP00000006528	ENSSGRP00000069817	Transcription factor AP-1-like.	Transcription factor AP-1-like.	0.900
ENSSGRP00000006528	LOC107563389	ENSSGRP00000006528	ENSSGRP00000088629	Transcription factor AP-1-like.	Transcription factor AP-1-like isoform X1.	0.900
ENSSGRP00000006528	LOC107582292	ENSSGRP00000006528	ENSSGRP00000034096	Transcription factor AP-1-like.	Lymphotoxin alpha (TNF superfamily, member 1).	0.507
ENSSGRP00000012381	ENSSGRP00000006394	ENSSGRP00000012381	ENSSGRP00000006394	annotation not available	annotation not available	0.496
ENSSGRP00000012381	LOC107582292	ENSSGRP00000012381	ENSSGRP00000034096	annotation not available	Lymphotoxin alpha (TNF superfamily, member 1).	0.496
ENSSGRP00000018523	LOC107551164	ENSSGRP00000018523	ENSSGRP00000023290	Interferon-induced 35 kDa protein-like.	Interferon-induced 35 kDa protein homolog.	0.948
ENSSGRP00000018523	LOC107561363	ENSSGRP00000018523	ENSSGRP00000026560	Interferon-induced 35 kDa protein-like.	Interferon-induced 35 kDa protein homolog isoform X1.	0.949
ENSSGRP00000055921	LOC107551164	ENSSGRP00000055921	ENSSGRP00000023290	N-myc-interactor-like.	Interferon-induced 35 kDa protein homolog.	0.946
ENSSGRP00000055921	LOC107561363	ENSSGRP00000055921	ENSSGRP00000026560	N-myc-interactor-like.	Interferon-induced 35 kDa protein homolog isoform X1.	0.947