(37 nodes) Modulation by host of viral process network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1362 aa)
	ENSSGRP00000110934	Parkin RBR E3 ubiquitin protein ligase. (455 aa)
	LOC107557470	TBC1 domain family member 20-like. (394 aa)
	LOC107548233	Pyruvate carboxylase, mitochondrial. (1234 aa)
	ENSSGRP00000103292	Proteasome 26S subunit, ATPase 3. (374 aa)
	ENSSGRP00000101551	Phosphatidylinositol 4-kinase, catalytic, alpha a. (1997 aa)
	PI4KA-2	Phosphatidylinositol 4-kinase alpha-like isoform X1. (1345 aa)
	phb	Prohibitin 1. (271 aa)
	LOC107551774	Ribonuclease ZC3H12A-like. (643 aa)
	psmc3	26S proteasome regulatory subunit T5. (431 aa)
	LOC107557839	Pentraxin-related protein PTX3-like. (453 aa)
	PI4KA	Phosphatidylinositol 4-kinase alpha. (1739 aa)
	LOC107560023	Peptidyl-prolyl cis-trans isomerase B (cyclophilin B). (216 aa)
	ENSSGRP00000076312	Early endosome antigen 1-like isoform X1. (1390 aa)
	LOC107603065	Cation-independent mannose-6-phosphate receptor-like. (2274 aa)
	LOC107559106	Pentraxin-related protein PTX3-like isoform X1. (450 aa)
	ENSSGRP00000068257	Pyruvate carboxylase, mitochondrial-like. (919 aa)
	ENSSGRP00000064762	Cation-independent mannose-6-phosphate receptor-like. (2295 aa)
	prkn	E3 ubiquitin-protein ligase parkin. (438 aa)
	LOC107591444	Pentraxin-related protein PTX3-like isoform X1. (449 aa)
	ENSSGRP00000060507	Prohibitin. (247 aa)
	LOC107553935	Early endosome antigen 1-like. (1369 aa)
	ENSSGRP00000050967	TBC1 domain family member 20-like isoform X1. (328 aa)
	LOC107586998	TBC1 domain family member 20-like. (391 aa)
	ENSSGRP00000042990	Zinc finger CCCH-type containing 12A. (167 aa)
	LOC107563506	Pentraxin-related protein PTX3-like. (452 aa)
	LOC107565168	Pyruvate carboxylase, mitochondrial-like. (1181 aa)
	Pi4ka	Phosphatidylinositol 4-kinase alpha. (1963 aa)
	ENSSGRP00000021098	annotation not available (139 aa)
	ENSSGRP00000016947	Pyruvate carboxylase, mitochondrial-like. (240 aa)
	LOC107573569	TBC1 domain family member 20-like isoform X1. (398 aa)
	ENSSGRP00000011614	Ribonuclease ZC3H12A-like. (567 aa)
	ENSSGRP00000009998	Pyruvate carboxylase, mitochondrial-like. (467 aa)
	ENSSGRP00000009562	Interferon alpha-inducible protein 27-like protein 2A. (67 aa)
	zc3h12a	Bifunctional endoribonuclease and deubiquitinase ZC3H12A. (643 aa)
	PPIB	Peptidyl-prolyl cis-trans isomerase B (cyclophilin B). (216 aa)
	YTHDC2	Probable ATP-dependent RNA helicase YTHDC2. (1302 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000009998	ENSSGRP00000016947	ENSSGRP00000009998	ENSSGRP00000016947	Pyruvate carboxylase, mitochondrial-like.	Pyruvate carboxylase, mitochondrial-like.	0.448
ENSSGRP00000016947	ENSSGRP00000009998	ENSSGRP00000016947	ENSSGRP00000009998	Pyruvate carboxylase, mitochondrial-like.	Pyruvate carboxylase, mitochondrial-like.	0.448
ENSSGRP00000060507	ENSSGRP00000103292	ENSSGRP00000060507	ENSSGRP00000103292	Prohibitin.	Proteasome 26S subunit, ATPase 3.	0.418
ENSSGRP00000060507	psmc3	ENSSGRP00000060507	ENSSGRP00000081697	Prohibitin.	26S proteasome regulatory subunit T5.	0.418
ENSSGRP00000064762	ENSSGRP00000076312	ENSSGRP00000064762	ENSSGRP00000076312	Cation-independent mannose-6-phosphate receptor-like.	Early endosome antigen 1-like isoform X1.	0.410
ENSSGRP00000064762	LOC107553935	ENSSGRP00000064762	ENSSGRP00000057987	Cation-independent mannose-6-phosphate receptor-like.	Early endosome antigen 1-like.	0.410
ENSSGRP00000076312	ENSSGRP00000064762	ENSSGRP00000076312	ENSSGRP00000064762	Early endosome antigen 1-like isoform X1.	Cation-independent mannose-6-phosphate receptor-like.	0.410
ENSSGRP00000076312	LOC107603065	ENSSGRP00000076312	ENSSGRP00000071209	Early endosome antigen 1-like isoform X1.	Cation-independent mannose-6-phosphate receptor-like.	0.410
ENSSGRP00000103292	ENSSGRP00000060507	ENSSGRP00000103292	ENSSGRP00000060507	Proteasome 26S subunit, ATPase 3.	Prohibitin.	0.418
ENSSGRP00000103292	phb	ENSSGRP00000103292	ENSSGRP00000090176	Proteasome 26S subunit, ATPase 3.	Prohibitin 1.	0.418
LOC107553935	ENSSGRP00000064762	ENSSGRP00000057987	ENSSGRP00000064762	Early endosome antigen 1-like.	Cation-independent mannose-6-phosphate receptor-like.	0.410
LOC107553935	LOC107603065	ENSSGRP00000057987	ENSSGRP00000071209	Early endosome antigen 1-like.	Cation-independent mannose-6-phosphate receptor-like.	0.410
LOC107603065	ENSSGRP00000076312	ENSSGRP00000071209	ENSSGRP00000076312	Cation-independent mannose-6-phosphate receptor-like.	Early endosome antigen 1-like isoform X1.	0.410
LOC107603065	LOC107553935	ENSSGRP00000071209	ENSSGRP00000057987	Cation-independent mannose-6-phosphate receptor-like.	Early endosome antigen 1-like.	0.410
PI4KA-2	Pi4ka	ENSSGRP00000101005	ENSSGRP00000028816	Phosphatidylinositol 4-kinase alpha-like isoform X1.	Phosphatidylinositol 4-kinase alpha.	0.901
Pi4ka	PI4KA-2	ENSSGRP00000028816	ENSSGRP00000101005	Phosphatidylinositol 4-kinase alpha.	Phosphatidylinositol 4-kinase alpha-like isoform X1.	0.901
phb	ENSSGRP00000103292	ENSSGRP00000090176	ENSSGRP00000103292	Prohibitin 1.	Proteasome 26S subunit, ATPase 3.	0.418
phb	psmc3	ENSSGRP00000090176	ENSSGRP00000081697	Prohibitin 1.	26S proteasome regulatory subunit T5.	0.418
psmc3	ENSSGRP00000060507	ENSSGRP00000081697	ENSSGRP00000060507	26S proteasome regulatory subunit T5.	Prohibitin.	0.418
psmc3	phb	ENSSGRP00000081697	ENSSGRP00000090176	26S proteasome regulatory subunit T5.	Prohibitin 1.	0.418