(40 nodes) T cell selection network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107581378	C-C chemokine receptor type 7-like. (372 aa)
	LOC107596557	T-cell-specific surface glycoprotein CD28-like. (229 aa)
	LOC107557647	T-cell surface glycoprotein CD3 delta chain-like. (173 aa)
	Cd3e	T-cell surface glycoprotein CD3 epsilon chain isoform X1. (172 aa)
	ENSSGRP00000026016	Tyrosine-protein kinase ZAP-70-like. (327 aa)
	ENSSGRP00000026013	Tyrosine-protein kinase ZAP-70-like. (546 aa)
	ENSSGRP00000023709	annotation not available (432 aa)
	BATF	Basic leucine zipper ATF-like transcription factor. (112 aa)
	ENSSGRP00000002215	annotation not available (73 aa)
	LOC107594963	Serine/threonine-protein kinase mTOR-like. (2549 aa)
	ENSSGRP00000019426	Protein THEMIS-like. (203 aa)
	ENSSGRP00000018198	Serum response factor-like. (238 aa)
	ENSSGRP00000015397	annotation not available (159 aa)
	ENSSGRP00000015396	T-cell surface glycoprotein CD3 epsilon chain-like. (163 aa)
	ENSSGRP00000009650	Caspase recruitment domain family, member 11. (810 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C-like. (1106 aa)
	Atg5	Autophagy-related protein 5. (253 aa)
	themis	Protein THEMIS. (684 aa)
	LOC107568266	Serum response factor-like isoform X1. (285 aa)
	LOC107554148	Protein THEMIS-like. (581 aa)
	LOC107594820	Interleukin-6 receptor subunit alpha-like isoform X1. (621 aa)
	ENSSGRP00000077961	Protein THEMIS2-like. (538 aa)
	ENSSGRP00000074557	Si:ch211-130m23.5. (524 aa)
	PTPRC-2	Protein tyrosine phosphatase receptor type C. (1160 aa)
	STK11	Serine/threonine kinase 11. (340 aa)
	ENSSGRP00000055176	Serum response factor-like. (238 aa)
	LOC107564227	Serine/threonine-protein kinase mTOR. (2552 aa)
	LOC107584769	C-C chemokine receptor type 7-like. (374 aa)
	LOC107569856	PiggyBac transposable element-derived protein 4-like. (424 aa)
	LOC107551382	Serum response factor-like. (524 aa)
	LOC107563776	T-box brain protein 1-like isoform X1. (608 aa)
	ENSSGRP00000098197	Thymocyte selection associated family member 2. (553 aa)
	batf	ATF-like basic leucine zipper transcriptional factor. (124 aa)
	ENSSGRP00000043576	Spleen tyrosine kinase. (526 aa)
	syk	Tyrosine-protein kinase SYK isoform X1. (608 aa)
	card11	Caspase recruitment domain-containing protein 11. (1137 aa)
	ENSSGRP00000034618	Autophagy-related protein 5. (163 aa)
	LOC107548917	Tyrosine-protein kinase ZAP-70-like. (623 aa)
	LOC107565723	T-box brain protein 1-like. (608 aa)
	ENSSGRP00000028534	annotation not available (173 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg5	ENSSGRP00000034618	ENSSGRP00000088289	ENSSGRP00000034618	Autophagy-related protein 5.	Autophagy-related protein 5.	0.900
Atg5	LOC107564227	ENSSGRP00000088289	ENSSGRP00000054966	Autophagy-related protein 5.	Serine/threonine-protein kinase mTOR.	0.632
Atg5	LOC107594963	ENSSGRP00000088289	ENSSGRP00000003759	Autophagy-related protein 5.	Serine/threonine-protein kinase mTOR-like.	0.632
Atg5	STK11	ENSSGRP00000088289	ENSSGRP00000061841	Autophagy-related protein 5.	Serine/threonine kinase 11.	0.440
BATF	ENSSGRP00000002215	ENSSGRP00000088812	ENSSGRP00000002215	Basic leucine zipper ATF-like transcription factor.	annotation not available	0.484
Cd3e	ENSSGRP00000015397	ENSSGRP00000028533	ENSSGRP00000015397	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	annotation not available	0.987
Cd3e	ENSSGRP00000026013	ENSSGRP00000028533	ENSSGRP00000026013	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Tyrosine-protein kinase ZAP-70-like.	0.887
Cd3e	ENSSGRP00000026016	ENSSGRP00000028533	ENSSGRP00000026016	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Tyrosine-protein kinase ZAP-70-like.	0.887
Cd3e	ENSSGRP00000043576	ENSSGRP00000028533	ENSSGRP00000043576	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Spleen tyrosine kinase.	0.887
Cd3e	ENSSGRP00000074557	ENSSGRP00000028533	ENSSGRP00000074557	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Si:ch211-130m23.5.	0.987
Cd3e	LOC107548917	ENSSGRP00000028533	ENSSGRP00000031195	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Tyrosine-protein kinase ZAP-70-like.	0.887
Cd3e	LOC107557647	ENSSGRP00000028533	ENSSGRP00000028535	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	T-cell surface glycoprotein CD3 delta chain-like.	0.987
Cd3e	LOC107569856	ENSSGRP00000028533	ENSSGRP00000047682	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	PiggyBac transposable element-derived protein 4-like.	0.987
Cd3e	LOC107581378	ENSSGRP00000028533	ENSSGRP00000108698	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	C-C chemokine receptor type 7-like.	0.494
Cd3e	LOC107584769	ENSSGRP00000028533	ENSSGRP00000054039	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	C-C chemokine receptor type 7-like.	0.494
Cd3e	LOC107596557	ENSSGRP00000028533	ENSSGRP00000110790	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	T-cell-specific surface glycoprotein CD28-like.	0.516
Cd3e	PTPRC	ENSSGRP00000028533	ENSSGRP00000008251	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Receptor-type tyrosine-protein phosphatase C-like.	0.748
Cd3e	PTPRC-2	ENSSGRP00000028533	ENSSGRP00000063515	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Protein tyrosine phosphatase receptor type C.	0.748
Cd3e	syk	ENSSGRP00000028533	ENSSGRP00000040643	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Tyrosine-protein kinase SYK isoform X1.	0.887
ENSSGRP00000002215	BATF	ENSSGRP00000002215	ENSSGRP00000088812	annotation not available	Basic leucine zipper ATF-like transcription factor.	0.484