(27 nodes) Regulation of macrophage differentiation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107564749	Interferon regulatory factor 2-binding protein 2-B-like. (489 aa)
	LOC107589304	Transforming growth factor beta-1-like. (381 aa)
	ENSSGRP00000091896	Colony stimulating factor 1a (macrophage). (518 aa)
	il34	Interleukin 34. (210 aa)
	LOC107573058	Transforming growth factor beta-1. (380 aa)
	ENSSGRP00000059246	Interleukin 34. (181 aa)
	LOC107598564	Transforming growth factor beta-1-like. (376 aa)
	LOC107567632	Interferon regulatory factor 2-binding protein 2-B. (506 aa)
	ENSSGRP00000087331	Caspase-8-like. (228 aa)
	LOC107559437	FAS-associated death domain protein-like. (192 aa)
	LOC107566714	Adiponectin-like. (276 aa)
	ENSSGRP00000082889	Colony stimulating factor 1b (macrophage). (263 aa)
	ENSSGRP00000087301	annotation not available (286 aa)
	LOC107548180	Retinoblastoma-associated protein-like. (915 aa)
	ENSSGRP00000097545	Complement component 1, q subcomponent, C chain. (218 aa)
	ENSSGRP00000006151	Caspase-8-like isoform X1. (152 aa)
	LOC107551612	Complement C1q subcomponent subunit C-like. (269 aa)
	ENSSGRP00000028599	Retinoblastoma 1. (841 aa)
	ENSSGRP00000029534	Caspase-8-like. (202 aa)
	ENSSGRP00000029537	annotation not available (218 aa)
	ENSSGRP00000031237	Caspase-8-like. (477 aa)
	LOC107555418	Caspase-8-like. (324 aa)
	ENSSGRP00000031485	Caspase-8-like. (140 aa)
	ENSSGRP00000034839	Caspase 10, apoptosis-related cysteine peptidase. (471 aa)
	ENSSGRP00000037912	Transforming growth factor beta-1-like. (376 aa)
	ENSSGRP00000112857	Uncharacterized protein LOC107550906. (252 aa)
	LOC107556909	Macrophage colony-stimulating factor 1. (546 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000006151	LOC107559437	ENSSGRP00000006151	ENSSGRP00000074211	Caspase-8-like isoform X1.	FAS-associated death domain protein-like.	0.958
ENSSGRP00000029534	LOC107559437	ENSSGRP00000029534	ENSSGRP00000074211	Caspase-8-like.	FAS-associated death domain protein-like.	0.969
ENSSGRP00000029537	LOC107559437	ENSSGRP00000029537	ENSSGRP00000074211	annotation not available	FAS-associated death domain protein-like.	0.967
ENSSGRP00000031237	LOC107559437	ENSSGRP00000031237	ENSSGRP00000074211	Caspase-8-like.	FAS-associated death domain protein-like.	0.997
ENSSGRP00000031485	LOC107559437	ENSSGRP00000031485	ENSSGRP00000074211	Caspase-8-like.	FAS-associated death domain protein-like.	0.969
ENSSGRP00000034839	LOC107559437	ENSSGRP00000034839	ENSSGRP00000074211	Caspase 10, apoptosis-related cysteine peptidase.	FAS-associated death domain protein-like.	0.958
ENSSGRP00000059246	ENSSGRP00000082889	ENSSGRP00000059246	ENSSGRP00000082889	Interleukin 34.	Colony stimulating factor 1b (macrophage).	0.822
ENSSGRP00000059246	ENSSGRP00000091896	ENSSGRP00000059246	ENSSGRP00000091896	Interleukin 34.	Colony stimulating factor 1a (macrophage).	0.822
ENSSGRP00000059246	ENSSGRP00000112857	ENSSGRP00000059246	ENSSGRP00000112857	Interleukin 34.	Uncharacterized protein LOC107550906.	0.822
ENSSGRP00000059246	LOC107556909	ENSSGRP00000059246	ENSSGRP00000104563	Interleukin 34.	Macrophage colony-stimulating factor 1.	0.822
ENSSGRP00000082889	ENSSGRP00000059246	ENSSGRP00000082889	ENSSGRP00000059246	Colony stimulating factor 1b (macrophage).	Interleukin 34.	0.822
ENSSGRP00000082889	il34	ENSSGRP00000082889	ENSSGRP00000053257	Colony stimulating factor 1b (macrophage).	Interleukin 34.	0.822
ENSSGRP00000087301	LOC107559437	ENSSGRP00000087301	ENSSGRP00000074211	annotation not available	FAS-associated death domain protein-like.	0.958
ENSSGRP00000087331	LOC107559437	ENSSGRP00000087331	ENSSGRP00000074211	Caspase-8-like.	FAS-associated death domain protein-like.	0.958
ENSSGRP00000091896	ENSSGRP00000059246	ENSSGRP00000091896	ENSSGRP00000059246	Colony stimulating factor 1a (macrophage).	Interleukin 34.	0.822
ENSSGRP00000091896	il34	ENSSGRP00000091896	ENSSGRP00000053257	Colony stimulating factor 1a (macrophage).	Interleukin 34.	0.822
ENSSGRP00000112857	ENSSGRP00000059246	ENSSGRP00000112857	ENSSGRP00000059246	Uncharacterized protein LOC107550906.	Interleukin 34.	0.822
ENSSGRP00000112857	il34	ENSSGRP00000112857	ENSSGRP00000053257	Uncharacterized protein LOC107550906.	Interleukin 34.	0.822
LOC107555418	LOC107559437	ENSSGRP00000031239	ENSSGRP00000074211	Caspase-8-like.	FAS-associated death domain protein-like.	0.997
LOC107556909	ENSSGRP00000059246	ENSSGRP00000104563	ENSSGRP00000059246	Macrophage colony-stimulating factor 1.	Interleukin 34.	0.822