(45 nodes) Negative regulation of osteoblast differentiation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107590890	DNA-binding protein inhibitor ID-3-like. (114 aa)
	LOC107590891	DNA-binding protein inhibitor ID-3-like. (114 aa)
	tnfaip6	Tumor necrosis factor-inducible gene 6 protein. (263 aa)
	Men1	LOW QUALITY PROTEIN: menin. (598 aa)
	ENSSGRP00000079987	Next to BRCA1 gene 1 protein-like. (896 aa)
	LOC107566715	BMP and activin membrane-bound inhibitor homolog. (257 aa)
	LOC107554134	Next to BRCA1 gene 1 protein-like. (998 aa)
	LOC107592316	Nuclear receptor ROR-beta-like isoform X1. (524 aa)
	ENSSGRP00000102356	Twist-related protein-like. (165 aa)
	ENSSGRP00000094346	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b. (162 aa)
	LOC107563986	Nocturnin-like isoform X1. (352 aa)
	LOC107549411	BMP and activin membrane-bound inhibitor homolog. (261 aa)
	ENSSGRP00000005806	Twist2. (166 aa)
	LOC107580862	BMP and activin membrane-bound inhibitor homolog. (148 aa)
	ENSSGRP00000006394	annotation not available (243 aa)
	ENSSGRP00000007390	annotation not available (148 aa)
	ENSSGRP00000010365	Cbp/p300-interacting transactivator 1-like. (143 aa)
	LOC107586734	Osteocrin-like. (134 aa)
	LOC107562977	Nocturnin-like. (398 aa)
	ENSSGRP00000013071	Twist-related protein-like. (176 aa)
	LOC107599811	Ski oncogene-like. (726 aa)
	LOC107569456	Insulin-like growth factor-binding protein 5. (267 aa)
	LOC107552731	Next to BRCA1 gene 1 protein-like. (776 aa)
	LOC107548407	Ski oncogene-like. (726 aa)
	ENSSGRP00000021574	Menin-like. (428 aa)
	ENSSGRP00000030429	Twist-related protein-like isoform X1. (164 aa)
	ENSSGRP00000031884	Transmembrane protein 64. (246 aa)
	LOC107586331	Insulin-like growth factor-binding protein 5. (264 aa)
	LOC107582223	Osteocrin-like. (128 aa)
	LOC107582292	Lymphotoxin alpha (TNF superfamily, member 1). (244 aa)
	ENSSGRP00000040743	Nocturnin-like isoform X1. (410 aa)
	LOC107583515	DNA-binding protein inhibitor ID-3-like. (114 aa)
	LOC107558783	Vascular endothelial growth factor C-like isoform X1. (397 aa)
	ENSSGRP00000044940	Gremlin-1-like. (168 aa)
	LOC107599920	Nuclear receptor ROR-beta-like isoform X1. (544 aa)
	LOC107584374	BMP and activin membrane-bound inhibitor homolog. (261 aa)
	LOC107555563	Transmembrane protein 64-like isoform X1. (347 aa)
	tnn	Tenascin-N isoform X1. (1020 aa)
	ENSSGRP00000064359	Tenascin N. (922 aa)
	ENSSGRP00000065083	Vascular endothelial growth factor c. (385 aa)
	Noct	Nocturnin. (430 aa)
	ENSSGRP00000112134	Twist-related protein 2-like isoform X1. (163 aa)
	ENSSGRP00000111487	Next to BRCA1 gene 1 protein-like isoform X1. (884 aa)
	LOC107555349	Tumor necrosis factor-inducible gene 6 protein-like. (267 aa)
	ENSSGRP00000109251	Cbp/p300-interacting transactivator 1-like. (157 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000006394	ENSSGRP00000079987	ENSSGRP00000006394	ENSSGRP00000079987	annotation not available	Next to BRCA1 gene 1 protein-like.	0.487
ENSSGRP00000006394	ENSSGRP00000111487	ENSSGRP00000006394	ENSSGRP00000111487	annotation not available	Next to BRCA1 gene 1 protein-like isoform X1.	0.487
ENSSGRP00000006394	LOC107552731	ENSSGRP00000006394	ENSSGRP00000015231	annotation not available	Next to BRCA1 gene 1 protein-like.	0.487
ENSSGRP00000006394	LOC107554134	ENSSGRP00000006394	ENSSGRP00000082648	annotation not available	Next to BRCA1 gene 1 protein-like.	0.487
ENSSGRP00000006394	LOC107555349	ENSSGRP00000006394	ENSSGRP00000110641	annotation not available	Tumor necrosis factor-inducible gene 6 protein-like.	0.633
ENSSGRP00000006394	tnfaip6	ENSSGRP00000006394	ENSSGRP00000067895	annotation not available	Tumor necrosis factor-inducible gene 6 protein.	0.633
ENSSGRP00000064359	tnn	ENSSGRP00000064359	ENSSGRP00000050501	Tenascin N.	Tenascin-N isoform X1.	0.485
ENSSGRP00000079987	ENSSGRP00000006394	ENSSGRP00000079987	ENSSGRP00000006394	Next to BRCA1 gene 1 protein-like.	annotation not available	0.487
ENSSGRP00000079987	ENSSGRP00000111487	ENSSGRP00000079987	ENSSGRP00000111487	Next to BRCA1 gene 1 protein-like.	Next to BRCA1 gene 1 protein-like isoform X1.	0.981
ENSSGRP00000079987	LOC107552731	ENSSGRP00000079987	ENSSGRP00000015231	Next to BRCA1 gene 1 protein-like.	Next to BRCA1 gene 1 protein-like.	0.980
ENSSGRP00000079987	LOC107554134	ENSSGRP00000079987	ENSSGRP00000082648	Next to BRCA1 gene 1 protein-like.	Next to BRCA1 gene 1 protein-like.	0.981
ENSSGRP00000079987	LOC107582292	ENSSGRP00000079987	ENSSGRP00000034096	Next to BRCA1 gene 1 protein-like.	Lymphotoxin alpha (TNF superfamily, member 1).	0.487
ENSSGRP00000111487	ENSSGRP00000006394	ENSSGRP00000111487	ENSSGRP00000006394	Next to BRCA1 gene 1 protein-like isoform X1.	annotation not available	0.487
ENSSGRP00000111487	ENSSGRP00000079987	ENSSGRP00000111487	ENSSGRP00000079987	Next to BRCA1 gene 1 protein-like isoform X1.	Next to BRCA1 gene 1 protein-like.	0.981
ENSSGRP00000111487	LOC107552731	ENSSGRP00000111487	ENSSGRP00000015231	Next to BRCA1 gene 1 protein-like isoform X1.	Next to BRCA1 gene 1 protein-like.	0.980
ENSSGRP00000111487	LOC107554134	ENSSGRP00000111487	ENSSGRP00000082648	Next to BRCA1 gene 1 protein-like isoform X1.	Next to BRCA1 gene 1 protein-like.	0.980
ENSSGRP00000111487	LOC107582292	ENSSGRP00000111487	ENSSGRP00000034096	Next to BRCA1 gene 1 protein-like isoform X1.	Lymphotoxin alpha (TNF superfamily, member 1).	0.487
LOC107552731	ENSSGRP00000006394	ENSSGRP00000015231	ENSSGRP00000006394	Next to BRCA1 gene 1 protein-like.	annotation not available	0.487
LOC107552731	ENSSGRP00000079987	ENSSGRP00000015231	ENSSGRP00000079987	Next to BRCA1 gene 1 protein-like.	Next to BRCA1 gene 1 protein-like.	0.980
LOC107552731	ENSSGRP00000111487	ENSSGRP00000015231	ENSSGRP00000111487	Next to BRCA1 gene 1 protein-like.	Next to BRCA1 gene 1 protein-like isoform X1.	0.980