(42 nodes) Negative regulation of Notch signaling pathway network (Sinocyclocheilus grahami)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000099790	Delta-like protein 4. (719 aa)
	ENSSGRP00000099788	ChaC, cation transport regulator homolog 1 (E. coli). (175 aa)
	ENSSGRP00000098472	Delta-like protein C isoform X1. (678 aa)
	TCIM	Protein C8orf4 homolog. (96 aa)
	ENSSGRP00000085642	Delta-like protein A. (789 aa)
	LOC107595277	N6-adenosine-methyltransferase subunit METTL3. (587 aa)
	LOC107588638	Hypoxia-inducible factor 1-alpha inhibitor (HIF hydroxylase). (365 aa)
	LOC107597844	NF-kappa-B inhibitor alpha-like. (337 aa)
	LOC107596148	Delta-like protein B. (647 aa)
	chac1	Glutathione-specific gamma-glutamylcyclotransferase 1. (196 aa)
	LOC107562694	Delta-like protein 4. (680 aa)
	LOC107550174	Solute carrier family 35 (GDP-fucose transporter), member C1. (302 aa)
	LOC107589639	NF-kappa-B inhibitor alpha-like isoform X1. (313 aa)
	ENSSGRP00000061758	deltaB. (255 aa)
	slc35c1	Solute carrier family 35 (GDP-fucose transporter), member C1. (360 aa)
	ENSSGRP00000054792	Neuronal differentiation 1. (303 aa)
	ENSSGRP00000050160	deltaA. (749 aa)
	LOC107585304	Hypoxia-inducible factor 1-alpha inhibitor (HIF hydroxylase). (366 aa)
	LOC107564214	Delta-like protein D. (608 aa)
	LOC107563042	Tetraspanin-15-like. (302 aa)
	LOC107595676	Arrestin domain-containing protein 1-like isoform X1. (442 aa)
	ythdf2	YTH domain-containing family protein 2. (613 aa)
	ENSSGRP00000032516	annotation not available (278 aa)
	Dll1	Delta-like protein 1. (749 aa)
	LOC107560293	N6-adenosine-methyltransferase subunit METTL3-like isoform X1. (582 aa)
	LOC107594995	Protein C8orf4 homolog. (100 aa)
	ENSSGRP00000021026	Delta-like protein C isoform X1. (671 aa)
	LOC107559779	Protein delta homolog 2-like isoform X1. (432 aa)
	LOC107594991	Tetraspanin-15-like. (351 aa)
	ENSSGRP00000014563	Epstein-Barr virus induced gene 2. (381 aa)
	LOC107601389	Neurogenic differentiation factor 1-like. (348 aa)
	DLK1	Delta like non-canonical Notch ligand 1. (307 aa)
	LOC107581491	NF-kappa-B inhibitor alpha-like. (311 aa)
	ENSSGRP00000006238	Delta-like protein B. (448 aa)
	ENSSGRP00000005354	Glutathione-specific gamma-glutamylcyclotransferase 1-like. (184 aa)
	ENSSGRP00000001716	Zgc:110329. (328 aa)
	LOC107587466	Protein C8orf4 homolog. (100 aa)
	TCIM-2	Protein C8orf4 homolog. (100 aa)
	LOC107548797	Arrestin domain-containing protein 1-like. (445 aa)
	ENSSGRP00000102613	Tetraspanin-15-like. (297 aa)
	LOC107569509	G-protein coupled receptor 183-A-like. (372 aa)
	LOC107586612	NF-kappa-B inhibitor alpha-like isoform X1. (309 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000005354	chac1	ENSSGRP00000005354	ENSSGRP00000071529	Glutathione-specific gamma-glutamylcyclotransferase 1-like.	Glutathione-specific gamma-glutamylcyclotransferase 1.	0.900
LOC107560293	ythdf2	ENSSGRP00000024718	ENSSGRP00000041330	N6-adenosine-methyltransferase subunit METTL3-like isoform X1.	YTH domain-containing family protein 2.	0.620
LOC107595277	ythdf2	ENSSGRP00000082773	ENSSGRP00000041330	N6-adenosine-methyltransferase subunit METTL3.	YTH domain-containing family protein 2.	0.620
chac1	ENSSGRP00000005354	ENSSGRP00000071529	ENSSGRP00000005354	Glutathione-specific gamma-glutamylcyclotransferase 1.	Glutathione-specific gamma-glutamylcyclotransferase 1-like.	0.900
ythdf2	LOC107560293	ENSSGRP00000041330	ENSSGRP00000024718	YTH domain-containing family protein 2.	N6-adenosine-methyltransferase subunit METTL3-like isoform X1.	0.620
ythdf2	LOC107595277	ENSSGRP00000041330	ENSSGRP00000082773	YTH domain-containing family protein 2.	N6-adenosine-methyltransferase subunit METTL3.	0.620