(25 nodes) Positive regulation of smoothened signaling pathway network (Sinocyclocheilus grahami)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	armc9	LisH domain-containing protein ARMC9. (727 aa)
	ENSSGRP00000106720	Smoothened homolog. (662 aa)
	LOC107556364	Protein FAM92A1 isoform X1. (295 aa)
	ENSSGRP00000098091	annotation not available (148 aa)
	ENSSGRP00000098086	Growth arrest-specific protein 1-like. (251 aa)
	ENSSGRP00000086642	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1. (1022 aa)
	ENSSGRP00000085579	Disks large homolog 5-like. (1811 aa)
	txndc15	Thioredoxin domain-containing protein 15. (271 aa)
	ENSSGRP00000082114	Growth arrest-specific 8. (309 aa)
	ENSSGRP00000073961	Ubiquitin carboxyl-terminal hydrolase isozyme L5-like. (344 aa)
	ENSSGRP00000070623	Ubiquitin carboxyl-terminal hydrolase isozyme L5-like. (323 aa)
	ENSSGRP00000069256	annotation not available (701 aa)
	ENSSGRP00000068010	Disks large homolog 5-like isoform X1. (1877 aa)
	ENSSGRP00000058267	annotation not available (1810 aa)
	ENSSGRP00000056849	Signal peptide, CUB and EGF-like domain-containing protein 3. (910 aa)
	LOC107592233	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1. (1023 aa)
	ENSSGRP00000045234	Growth arrest-specific protein 1-like. (266 aa)
	ENSSGRP00000045232	Serine/threonine-protein kinase ULK3-like. (427 aa)
	LOC107565208	Protein FAM92A1-like isoform X1. (291 aa)
	ENSSGRP00000035649	Disks large homolog 5-like. (1876 aa)
	ENSSGRP00000029076	LisH domain-containing protein ARMC9-like isoform X1. (550 aa)
	ENSSGRP00000027440	Uncharacterized protein LOC107598122. (1010 aa)
	ENSSGRP00000015281	annotation not available (247 aa)
	Evc	Ellis van creveld syndrome protein 1. (542 aa)
	ENSSGRP00000012895	Growth arrest-specific protein 8-like. (216 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000012895	ENSSGRP00000106720	ENSSGRP00000012895	ENSSGRP00000106720	Growth arrest-specific protein 8-like.	Smoothened homolog.	0.819
ENSSGRP00000015281	ENSSGRP00000106720	ENSSGRP00000015281	ENSSGRP00000106720	annotation not available	Smoothened homolog.	0.917
ENSSGRP00000027440	ENSSGRP00000106720	ENSSGRP00000027440	ENSSGRP00000106720	Uncharacterized protein LOC107598122.	Smoothened homolog.	0.917
ENSSGRP00000029076	txndc15	ENSSGRP00000029076	ENSSGRP00000082315	LisH domain-containing protein ARMC9-like isoform X1.	Thioredoxin domain-containing protein 15.	0.521
ENSSGRP00000035649	Evc	ENSSGRP00000035649	ENSSGRP00000014655	Disks large homolog 5-like.	Ellis van creveld syndrome protein 1.	0.505
ENSSGRP00000045234	ENSSGRP00000098086	ENSSGRP00000045234	ENSSGRP00000098086	Growth arrest-specific protein 1-like.	Growth arrest-specific protein 1-like.	0.901
ENSSGRP00000045234	ENSSGRP00000106720	ENSSGRP00000045234	ENSSGRP00000106720	Growth arrest-specific protein 1-like.	Smoothened homolog.	0.688
ENSSGRP00000056849	ENSSGRP00000086642	ENSSGRP00000056849	ENSSGRP00000086642	Signal peptide, CUB and EGF-like domain-containing protein 3.	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1.	0.450
ENSSGRP00000056849	LOC107592233	ENSSGRP00000056849	ENSSGRP00000054830	Signal peptide, CUB and EGF-like domain-containing protein 3.	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1.	0.449
ENSSGRP00000058267	Evc	ENSSGRP00000058267	ENSSGRP00000014655	annotation not available	Ellis van creveld syndrome protein 1.	0.505
ENSSGRP00000068010	Evc	ENSSGRP00000068010	ENSSGRP00000014655	Disks large homolog 5-like isoform X1.	Ellis van creveld syndrome protein 1.	0.452
ENSSGRP00000069256	ENSSGRP00000086642	ENSSGRP00000069256	ENSSGRP00000086642	annotation not available	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1.	0.448
ENSSGRP00000069256	LOC107592233	ENSSGRP00000069256	ENSSGRP00000054830	annotation not available	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1.	0.448
ENSSGRP00000082114	ENSSGRP00000106720	ENSSGRP00000082114	ENSSGRP00000106720	Growth arrest-specific 8.	Smoothened homolog.	0.819
ENSSGRP00000085579	Evc	ENSSGRP00000085579	ENSSGRP00000014655	Disks large homolog 5-like.	Ellis van creveld syndrome protein 1.	0.505
ENSSGRP00000086642	ENSSGRP00000056849	ENSSGRP00000086642	ENSSGRP00000056849	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1.	Signal peptide, CUB and EGF-like domain-containing protein 3.	0.450
ENSSGRP00000086642	ENSSGRP00000069256	ENSSGRP00000086642	ENSSGRP00000069256	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1.	annotation not available	0.448
ENSSGRP00000098086	ENSSGRP00000045234	ENSSGRP00000098086	ENSSGRP00000045234	Growth arrest-specific protein 1-like.	Growth arrest-specific protein 1-like.	0.901
ENSSGRP00000098086	ENSSGRP00000106720	ENSSGRP00000098086	ENSSGRP00000106720	Growth arrest-specific protein 1-like.	Smoothened homolog.	0.688
ENSSGRP00000106720	ENSSGRP00000012895	ENSSGRP00000106720	ENSSGRP00000012895	Smoothened homolog.	Growth arrest-specific protein 8-like.	0.819