(35 nodes) Mesodermal cell differentiation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000108829	Integrin, alpha 3a. (835 aa)
	LOC107556731	Lysine-specific demethylase 6A-like. (1386 aa)
	LOC107591795	Transcription initiation factor TFIID subunit 10-like. (188 aa)
	ENSSGRP00000057916	Integrin beta-4-like. (1887 aa)
	ENSSGRP00000056598	Lysocardiolipin acyltransferase 1. (354 aa)
	bmp2	Bone morphogenetic protein 2. (388 aa)
	ENSSGRP00000053783	Lysine (K)-specific demethylase 6A, like. (1209 aa)
	kdm6b	Lysine-specific demethylase 6B. (2020 aa)
	LOC107557321	Integrin alpha-3-like. (914 aa)
	ENSSGRP00000086417	annotation not available (99 aa)
	LOC107553925	Visual system homeobox 1-like isoform X1. (343 aa)
	LOC107586158	Lysine-specific demethylase 6B-like isoform X1. (1714 aa)
	ENSSGRP00000097852	LOW QUALITY PROTEIN: forkhead box protein H1-like. (472 aa)
	LOC107593250	Bone morphogenetic protein 2-like. (411 aa)
	LOC107601250	Integrin alpha-3-like isoform X1. (1058 aa)
	kdm6a	Lysine-specific demethylase 6A isoform X1. (1419 aa)
	Sfrp2	Secreted frizzled-related protein 2. (308 aa)
	LOC107569960	Mesogenin-1-like. (114 aa)
	ENSSGRP00000049999	Integrin beta-4-like. (1873 aa)
	LOC107602559	Wingless-type MMTV integration site family, member 8. (354 aa)
	ENSSGRP00000038800	Wingless-type MMTV integration site family, member 8a. (346 aa)
	LOC107552890	Bone morphogenetic protein 2-like. (388 aa)
	LOC107568033	Lysocardiolipin and lysophospholipid acyltransferase. (372 aa)
	LOC107550511	Transcription initiation factor TFIID subunit 10-like isoform X1. (189 aa)
	LOC107568470	Secreted frizzled-related protein 2-like. (308 aa)
	ENSSGRP00000022067	Bone morphogenetic protein 2-like. (332 aa)
	LOC107554308	Lysine-specific demethylase 6B-like isoform X1. (1682 aa)
	ENSSGRP00000005880	T-cell acute lymphocytic leukemia protein 1 homolog. (183 aa)
	ENSSGRP00000000830	High mobility group AT-hook 2. (84 aa)
	LOC107583698	Visual system homeobox 1 isoform X1. (344 aa)
	LOC107568687	Wingless-type MMTV integration site family, member 8. (359 aa)
	LOC107568688	Wingless-type MMTV integration site family, member 8. (336 aa)
	ENSSGRP00000071108	T-cell acute lymphocytic leukemia 1. (324 aa)
	itga3	Integrin alpha 3. (999 aa)
	ENSSGRP00000067024	LOW QUALITY PROTEIN: forkhead box protein H1-like. (450 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000038800	LOC107568470	ENSSGRP00000038800	ENSSGRP00000022680	Wingless-type MMTV integration site family, member 8a.	Secreted frizzled-related protein 2-like.	0.447
ENSSGRP00000038800	Sfrp2	ENSSGRP00000038800	ENSSGRP00000053156	Wingless-type MMTV integration site family, member 8a.	Secreted frizzled-related protein 2.	0.501
ENSSGRP00000049999	ENSSGRP00000057916	ENSSGRP00000049999	ENSSGRP00000057916	Integrin beta-4-like.	Integrin beta-4-like.	0.900
ENSSGRP00000049999	ENSSGRP00000108829	ENSSGRP00000049999	ENSSGRP00000108829	Integrin beta-4-like.	Integrin, alpha 3a.	0.811
ENSSGRP00000049999	LOC107557321	ENSSGRP00000049999	ENSSGRP00000083902	Integrin beta-4-like.	Integrin alpha-3-like.	0.811
ENSSGRP00000049999	LOC107601250	ENSSGRP00000049999	ENSSGRP00000064724	Integrin beta-4-like.	Integrin alpha-3-like isoform X1.	0.811
ENSSGRP00000049999	itga3	ENSSGRP00000049999	ENSSGRP00000069086	Integrin beta-4-like.	Integrin alpha 3.	0.811
ENSSGRP00000057916	ENSSGRP00000049999	ENSSGRP00000057916	ENSSGRP00000049999	Integrin beta-4-like.	Integrin beta-4-like.	0.900
ENSSGRP00000057916	ENSSGRP00000108829	ENSSGRP00000057916	ENSSGRP00000108829	Integrin beta-4-like.	Integrin, alpha 3a.	0.811
ENSSGRP00000057916	LOC107557321	ENSSGRP00000057916	ENSSGRP00000083902	Integrin beta-4-like.	Integrin alpha-3-like.	0.811
ENSSGRP00000057916	LOC107601250	ENSSGRP00000057916	ENSSGRP00000064724	Integrin beta-4-like.	Integrin alpha-3-like isoform X1.	0.811
ENSSGRP00000057916	itga3	ENSSGRP00000057916	ENSSGRP00000069086	Integrin beta-4-like.	Integrin alpha 3.	0.811
ENSSGRP00000108829	ENSSGRP00000049999	ENSSGRP00000108829	ENSSGRP00000049999	Integrin, alpha 3a.	Integrin beta-4-like.	0.811
ENSSGRP00000108829	ENSSGRP00000057916	ENSSGRP00000108829	ENSSGRP00000057916	Integrin, alpha 3a.	Integrin beta-4-like.	0.811
LOC107550511	LOC107591795	ENSSGRP00000027160	ENSSGRP00000060228	Transcription initiation factor TFIID subunit 10-like isoform X1.	Transcription initiation factor TFIID subunit 10-like.	0.900
LOC107557321	ENSSGRP00000049999	ENSSGRP00000083902	ENSSGRP00000049999	Integrin alpha-3-like.	Integrin beta-4-like.	0.811
LOC107557321	ENSSGRP00000057916	ENSSGRP00000083902	ENSSGRP00000057916	Integrin alpha-3-like.	Integrin beta-4-like.	0.811
LOC107557321	LOC107601250	ENSSGRP00000083902	ENSSGRP00000064724	Integrin alpha-3-like.	Integrin alpha-3-like isoform X1.	0.903
LOC107557321	itga3	ENSSGRP00000083902	ENSSGRP00000069086	Integrin alpha-3-like.	Integrin alpha 3.	0.901
LOC107568470	ENSSGRP00000038800	ENSSGRP00000022680	ENSSGRP00000038800	Secreted frizzled-related protein 2-like.	Wingless-type MMTV integration site family, member 8a.	0.447