(120 nodes) Embryonic cranial skeleton morphogenesis network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107597631	Follistatin-A-like isoform X1. (344 aa)
	LOC107595577	Follistatin-A-like isoform X1. (319 aa)
	LOC107570386	[histone H3]-dimethyl-L-lysine9 demethylase. (1032 aa)
	LOC107548884	Activated leukocyte cell adhesion molecule. (564 aa)
	ENSSGRP00000018200	Caspase-1-A-like. (386 aa)
	ENSSGRP00000019785	Transforming growth factor beta receptor 2a. (511 aa)
	ENSSGRP00000022067	Bone morphogenetic protein 2-like. (332 aa)
	LOC107581671	Noggin-3-like. (223 aa)
	ENSSGRP00000023653	Activated leukocyte cell adhesion molecule. (557 aa)
	SETD2	Histone-lysine N-methyltransferase SETD2-like. (2565 aa)
	ENSSGRP00000023758	Caspase-1-A-like. (374 aa)
	gata3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (440 aa)
	dlx1	Homeobox protein DLX1/4/6. (252 aa)
	dlx2	Homeobox protein DLX-2. (271 aa)
	LOC107591663	Homeobox protein Dlx5a-like. (283 aa)
	LOC107593250	Bone morphogenetic protein 2-like. (411 aa)
	LOC107550703	Tiggy-winkle hedgehog protein-like. (416 aa)
	LOC107592120	Double-strand-break repair protein rad21 homolog isoform X1. (635 aa)
	LOC107589914	E3 ubiquitin-protein ligase RING2-like. (234 aa)
	LOC107588322	Platelet-derived growth factor receptor beta-like. (1065 aa)
	LOC107591558	WD repeat-containing protein 19-like isoform X1. (1356 aa)
	ilvbl	Acetolactate synthase-like protein. (640 aa)
	LOC107588237	Homeobox protein Dlx2a. (274 aa)
	LOC107588239	Homeobox protein Dlx1a-like. (250 aa)
	ENSSGRP00000100208	Double-strand-break repair protein rad21 homolog. (646 aa)
	LOC107586586	Protein transport protein Sec23A-like. (751 aa)
	LOC107588193	Cytochrome P450 family 26 subfamily B. (511 aa)
	tbx1	T-box transcription factor TBX1 isoform X1. (519 aa)
	LOC107597537	Activated leukocyte cell adhesion molecule. (557 aa)
	LOC107554690	Mediator of RNA polymerase II transcription subunit 12. (2073 aa)
	LOC107555822	Transcription factor GATA-3 isoform X1. (440 aa)
	LOC107591009	Sonic hedgehog protein A-like. (418 aa)
	ENSSGRP00000000322	Lysyl oxidase-like 3b. (770 aa)
	ENSSGRP00000092927	Receptor-type tyrosine-protein kinase FLT3-like. (382 aa)
	LOC107590993	RanBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1. (716 aa)
	LOC107596814	Sphingosine 1-phosphate receptor 2-like. (370 aa)
	LOC107591968	RNA-binding protein 24-like. (229 aa)
	LOC107591962	Double-strand-break repair protein rad21 homolog isoform X1. (637 aa)
	Disp1	Protein dispatched homolog 1. (1484 aa)
	LOC107588741	Fibroblast growth factor 8-like. (210 aa)
	LOC107562039	Cytochrome P450 family 26 subfamily B. (511 aa)
	mmachc	Cyanocobalamin reductase (cyanide-eliminating) / alkylcobalamin dealkylase. (259 aa)
	leo1	RNA polymerase-associated protein LEO1. (621 aa)
	LOC107557343	Homeobox protein Dlx3b-like. (269 aa)
	LOC107557342	Homeobox protein Dlx4b isoform X1. (255 aa)
	LOC107599173	Follistatin-A isoform X1. (349 aa)
	LOC107582399	Wingless-type MMTV integration site family, member 4. (352 aa)
	ENSSGRP00000076066	Neuroblastoma-amplified sequence. (1882 aa)
	LOC107586383	Tiggy-winkle hedgehog protein. (416 aa)
	ENSSGRP00000075074	annotation not available (211 aa)
	ENSSGRP00000075071	Platelet-derived growth factor receptor alpha. (1061 aa)
	Gnptab	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. (1099 aa)
	FAM20B	Glycosaminoglycan xylosylkinase-like. (387 aa)
	dlx5	Homeobox protein DLX-5. (283 aa)
	LOC107598678	Homeobox protein Dlx3b. (269 aa)
	ENSSGRP00000065455	Homeobox protein aristaless-like 3. (183 aa)
	LOC107568221	Protein dispatched homolog 1-like. (1491 aa)
	LOC107556071	RanBP-type and C3HC4-type zinc finger-containing protein 1-like. (716 aa)
	LOC107552491	Heart- and neural crest derivatives-expressed protein 2. (208 aa)
	LOC107556063	Sonic hedgehog protein A. (418 aa)
	mab21l2	Protein mab-21-like 2. (359 aa)
	LOC107563633	[histone H3]-dimethyl-L-lysine9 demethylase. (1033 aa)
	ENSSGRP00000061739	Acetolactate synthase-like protein. (554 aa)
	LOC107589610	Protein transport protein Sec23A. (767 aa)
	LOC107565300	RNA-binding protein 24-A-like isoform X1. (223 aa)
	LOC107592929	RNA-binding protein 24. (229 aa)
	ENSSGRP00000055564	annotation not available (498 aa)
	bmp2	Bone morphogenetic protein 2. (388 aa)
	ENSSGRP00000054226	NIPBL cohesin loading factor a. (2321 aa)
	LOC107602023	Follistatin-A-like isoform X1. (346 aa)
	ENSSGRP00000053827	Fibroblast growth factor 8a. (206 aa)
	pitx2	Paired-like homeodomain transcription factor 2. (311 aa)
	LOC107572035	Wingless-type MMTV integration site family, member 5. (380 aa)
	ENSSGRP00000050347	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like. (149 aa)
	LOC107553896	Wingless-type MMTV integration site family, member 5. (374 aa)
	ENSSGRP00000001964	annotation not available (53 aa)
	ENSSGRP00000002159	annotation not available (384 aa)
	ENSSGRP00000002492	LOW QUALITY PROTEIN: nipped-B-like protein B. (256 aa)
	LOC107588329	Early growth response protein 1. (510 aa)
	nipbl	Cohesin loading factor subunit SCC2. (2723 aa)
	ENSSGRP00000046429	Double-strand-break repair protein rad21 homolog. (634 aa)
	ENSSGRP00000045001	Paired-like homeodomain transcription factor 2. (311 aa)
	ENSSGRP00000044449	Heart- and neural crest derivatives-expressed protein 2-like. (208 aa)
	telo2	Intraflagellar transport protein 140 homolog. (1417 aa)
	ENSSGRP00000041033	LEO1 homolog, Paf1/RNA polymerase II complex component. (554 aa)
	ENSSGRP00000040476	LOW QUALITY PROTEIN: platelet-derived growth factor receptor beta-like. (1040 aa)
	ENSSGRP00000040199	Mediator complex subunit 12. (1828 aa)
	LOC107600517	TGF-beta receptor type-2-like isoform X1. (558 aa)
	LOC107564705	E3 ubiquitin-protein ligase RING2 isoform X1. (360 aa)
	ENSSGRP00000038808	Nipped-B-like protein B. (2402 aa)
	LOC107582249	Putative nucleotidyltransferase. (359 aa)
	LOC107587933	Sphingosine 1-phosphate receptor 2. (370 aa)
	ENSSGRP00000036904	T-box transcription factor 1. (434 aa)
	LOC107557684	Early growth response protein 1-like. (509 aa)
	LOC107552890	Bone morphogenetic protein 2-like. (388 aa)
	ENSSGRP00000035110	annotation not available (91 aa)
	LOC107570904	Caspase-1-A-like. (385 aa)
	LOC107565731	Wingless-type MMTV integration site family, member 4. (352 aa)
	ENSSGRP00000034416	Caspase-1-like. (393 aa)
	LOC107594572	Cohesin loading factor subunit SCC2. (2328 aa)
	LOC107571421	Caspase-1-A-like isoform X1. (402 aa)
	LOC107587182	Putative nucleotidyltransferase. (359 aa)
	ENSSGRP00000029252	Fibroblast growth factor 3. (237 aa)
	ENSSGRP00000027786	Platelet-derived growth factor receptor alpha-like. (1076 aa)
	LOC107551196	TGF-beta receptor type-2-like. (562 aa)
	ENSSGRP00000027136	Double-strand-break repair protein rad21-like protein 1. (453 aa)
	LOC107569139	TGF-beta receptor type-2-like. (667 aa)
	ENSSGRP00000026391	Mab-21-like 2. (321 aa)
	RING1	E3 ubiquitin-protein ligase RING2-A-like. (353 aa)
	fam20b	Glycosaminoglycan xylosylkinase. (409 aa)
	LOC107567817	E3 ubiquitin-protein ligase RING2-A-like. (352 aa)
	LOC107567844	Lysyl oxidase-like protein 2/3/4. (469 aa)
	ENSSGRP00000010025	[histone H3]-dimethyl-L-lysine36 N-methyltransferase. (2629 aa)
	ENSSGRP00000010660	annotation not available (308 aa)
	ENSSGRP00000010767	Activated leukocyte cell adhesion molecule. (635 aa)
	ENSSGRP00000011326	Intraflagellar transport protein 140 homolog. (697 aa)
	LOC107592160	Caspase-1-like. (391 aa)
	ENSSGRP00000013629	annotation not available (99 aa)
	ENSSGRP00000013739	Fibroblast growth factor 3. (246 aa)
	ENSSGRP00000017087	RNA polymerase I and III subunit D. (101 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Disp1	ENSSGRP00000044449	ENSSGRP00000086111	ENSSGRP00000044449	Protein dispatched homolog 1.	Heart- and neural crest derivatives-expressed protein 2-like.	0.512
Disp1	LOC107550703	ENSSGRP00000086111	ENSSGRP00000107173	Protein dispatched homolog 1.	Tiggy-winkle hedgehog protein-like.	0.892
Disp1	LOC107552491	ENSSGRP00000086111	ENSSGRP00000063804	Protein dispatched homolog 1.	Heart- and neural crest derivatives-expressed protein 2.	0.512
Disp1	LOC107556063	ENSSGRP00000086111	ENSSGRP00000063780	Protein dispatched homolog 1.	Sonic hedgehog protein A.	0.892
Disp1	LOC107586383	ENSSGRP00000086111	ENSSGRP00000075945	Protein dispatched homolog 1.	Tiggy-winkle hedgehog protein.	0.892
Disp1	LOC107591009	ENSSGRP00000086111	ENSSGRP00000094493	Protein dispatched homolog 1.	Sonic hedgehog protein A-like.	0.892
ENSSGRP00000002492	ENSSGRP00000010025	ENSSGRP00000002492	ENSSGRP00000010025	LOW QUALITY PROTEIN: nipped-B-like protein B.	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	0.702
ENSSGRP00000002492	ENSSGRP00000027136	ENSSGRP00000002492	ENSSGRP00000027136	LOW QUALITY PROTEIN: nipped-B-like protein B.	Double-strand-break repair protein rad21-like protein 1.	0.905
ENSSGRP00000002492	ENSSGRP00000046429	ENSSGRP00000002492	ENSSGRP00000046429	LOW QUALITY PROTEIN: nipped-B-like protein B.	Double-strand-break repair protein rad21 homolog.	0.905
ENSSGRP00000002492	ENSSGRP00000100208	ENSSGRP00000002492	ENSSGRP00000100208	LOW QUALITY PROTEIN: nipped-B-like protein B.	Double-strand-break repair protein rad21 homolog.	0.940
ENSSGRP00000002492	LOC107591962	ENSSGRP00000002492	ENSSGRP00000087705	LOW QUALITY PROTEIN: nipped-B-like protein B.	Double-strand-break repair protein rad21 homolog isoform X1.	0.905
ENSSGRP00000002492	LOC107592120	ENSSGRP00000002492	ENSSGRP00000107114	LOW QUALITY PROTEIN: nipped-B-like protein B.	Double-strand-break repair protein rad21 homolog isoform X1.	0.940
ENSSGRP00000002492	SETD2	ENSSGRP00000002492	ENSSGRP00000025666	LOW QUALITY PROTEIN: nipped-B-like protein B.	Histone-lysine N-methyltransferase SETD2-like.	0.702
ENSSGRP00000010025	ENSSGRP00000002492	ENSSGRP00000010025	ENSSGRP00000002492	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	LOW QUALITY PROTEIN: nipped-B-like protein B.	0.702
ENSSGRP00000010025	ENSSGRP00000038808	ENSSGRP00000010025	ENSSGRP00000038808	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	Nipped-B-like protein B.	0.702
ENSSGRP00000010025	ENSSGRP00000041033	ENSSGRP00000010025	ENSSGRP00000041033	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.762
ENSSGRP00000010025	ENSSGRP00000054226	ENSSGRP00000010025	ENSSGRP00000054226	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	NIPBL cohesin loading factor a.	0.702
ENSSGRP00000010025	LOC107563633	ENSSGRP00000010025	ENSSGRP00000062142	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	[histone H3]-dimethyl-L-lysine9 demethylase.	0.498
ENSSGRP00000010025	LOC107570386	ENSSGRP00000010025	ENSSGRP00000017644	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	[histone H3]-dimethyl-L-lysine9 demethylase.	0.498
ENSSGRP00000010025	LOC107594572	ENSSGRP00000010025	ENSSGRP00000033975	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	Cohesin loading factor subunit SCC2.	0.702