(49 nodes) Brain morphogenesis network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000022057	FA complementation group C. (551 aa)
	ENSSGRP00000019703	CDP-L-ribitol pyrophosphorylase A. (391 aa)
	ENSSGRP00000019399	annotation not available (50 aa)
	ctnna2	Catenin alpha-2. (558 aa)
	LOC107596578	Cytochrome P450 family 26 subfamily A. (494 aa)
	LOC107573466	Catenin alpha-2-like. (345 aa)
	ENSSGRP00000003997	Bardet-Biedl syndrome 1 protein-like. (437 aa)
	ENSSGRP00000055520	LOW QUALITY PROTEIN: neurofibromin-like. (2706 aa)
	LOC107597334	Solute carrier family 6 (neurotransmitter transporter, serotonin) member 4. (591 aa)
	ENSSGRP00000060320	Neurofibromin-like isoform X1. (2497 aa)
	LOC107591828	Zinc finger protein 335-like. (1532 aa)
	ENSSGRP00000067024	LOW QUALITY PROTEIN: forkhead box protein H1-like. (450 aa)
	LOC107593523	Cytochrome P450 family 26 subfamily A. (494 aa)
	ENSSGRP00000077979	Catenin alpha-2-like. (367 aa)
	ENSSGRP00000077935	Catenin (cadherin-associated protein), alpha 2. (576 aa)
	ENSSGRP00000076187	Bardet-Biedl syndrome 4 protein-like. (184 aa)
	Bbs4	Bardet-Biedl syndrome 4 protein. (186 aa)
	mkks	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin isoform X1. (533 aa)
	LOC107597471	Homeobox protein GSH. (238 aa)
	LOC107597470	Homeobox protein GSH. (242 aa)
	ENSSGRP00000073961	Ubiquitin carboxyl-terminal hydrolase isozyme L5-like. (344 aa)
	LOC107589714	Solute carrier family 6 (neurotransmitter transporter, serotonin) member 4. (646 aa)
	LOC107584458	Fanconi anemia group D2 protein-like. (1367 aa)
	LOC107557259	Laminin subunit gamma-1-like. (1593 aa)
	ENSSGRP00000070623	Ubiquitin carboxyl-terminal hydrolase isozyme L5-like. (323 aa)
	ENSSGRP00000026478	LOW QUALITY PROTEIN: Fanconi anemia group D2 protein-like. (1198 aa)
	ENSSGRP00000026637	Homeobox protein GSH. (238 aa)
	ENSSGRP00000034457	Laminin subunit gamma-1-like. (231 aa)
	ENSSGRP00000035276	Isoprenoid synthase domain-containing protein-like isoform X1. (373 aa)
	ENSSGRP00000038885	Neurofibromin-like. (2731 aa)
	ENSSGRP00000046665	Bardet-Biedl syndrome 4. (402 aa)
	ENSSGRP00000047641	Neurofibromin-like isoform X1. (2280 aa)
	dhx9	Laminin subunit gamma-1. (1632 aa)
	LOC107595929	Solute carrier family 6 (neurotransmitter transporter, serotonin) member 4. (591 aa)
	LOC107587218	Platelet-activating factor acetylhydrolase IB subunit alpha. (410 aa)
	ENSSGRP00000106720	Smoothened homolog. (662 aa)
	LOC107592620	Platelet-activating factor acetylhydrolase IB subunit alpha. (410 aa)
	ENSSGRP00000103843	Catenin alpha-1. (906 aa)
	ENSSGRP00000101239	annotation not available (644 aa)
	ENSSGRP00000097852	LOW QUALITY PROTEIN: forkhead box protein H1-like. (472 aa)
	ENSSGRP00000097096	annotation not available (758 aa)
	LOC107581938	Platelet-activating factor acetylhydrolase IB subunit alpha. (410 aa)
	LOC107602842	Fanconi anemia group C protein-like isoform X1. (603 aa)
	ENSSGRP00000088054	Laminin subunit gamma-3-like. (1598 aa)
	LOC107594862	Growth/differentiation factor 6-A-like. (425 aa)
	LOC107563371	Growth/differentiation factor 6-A-like. (425 aa)
	ENSSGRP00000085366	Methyltransferase-like protein 16. (702 aa)
	LOC107548586	Solute carrier family 6 (neurotransmitter transporter, serotonin) member 4. (658 aa)
	HESX1	HESX homeobox 1. (118 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bbs4	ENSSGRP00000003997	ENSSGRP00000076186	ENSSGRP00000003997	Bardet-Biedl syndrome 4 protein.	Bardet-Biedl syndrome 1 protein-like.	0.997
Bbs4	ENSSGRP00000106720	ENSSGRP00000076186	ENSSGRP00000106720	Bardet-Biedl syndrome 4 protein.	Smoothened homolog.	0.729
ENSSGRP00000003997	Bbs4	ENSSGRP00000003997	ENSSGRP00000076186	Bardet-Biedl syndrome 1 protein-like.	Bardet-Biedl syndrome 4 protein.	0.997
ENSSGRP00000003997	ENSSGRP00000046665	ENSSGRP00000003997	ENSSGRP00000046665	Bardet-Biedl syndrome 1 protein-like.	Bardet-Biedl syndrome 4.	0.997
ENSSGRP00000003997	ENSSGRP00000076187	ENSSGRP00000003997	ENSSGRP00000076187	Bardet-Biedl syndrome 1 protein-like.	Bardet-Biedl syndrome 4 protein-like.	0.997
ENSSGRP00000003997	ENSSGRP00000106720	ENSSGRP00000003997	ENSSGRP00000106720	Bardet-Biedl syndrome 1 protein-like.	Smoothened homolog.	0.907
ENSSGRP00000003997	mkks	ENSSGRP00000003997	ENSSGRP00000075635	Bardet-Biedl syndrome 1 protein-like.	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin isoform X1.	0.678
ENSSGRP00000022057	ENSSGRP00000026478	ENSSGRP00000022057	ENSSGRP00000026478	FA complementation group C.	LOW QUALITY PROTEIN: Fanconi anemia group D2 protein-like.	0.970
ENSSGRP00000022057	LOC107584458	ENSSGRP00000022057	ENSSGRP00000071905	FA complementation group C.	Fanconi anemia group D2 protein-like.	0.970
ENSSGRP00000026478	ENSSGRP00000022057	ENSSGRP00000026478	ENSSGRP00000022057	LOW QUALITY PROTEIN: Fanconi anemia group D2 protein-like.	FA complementation group C.	0.970
ENSSGRP00000026478	LOC107584458	ENSSGRP00000026478	ENSSGRP00000071905	LOW QUALITY PROTEIN: Fanconi anemia group D2 protein-like.	Fanconi anemia group D2 protein-like.	0.900
ENSSGRP00000026478	LOC107602842	ENSSGRP00000026478	ENSSGRP00000091455	LOW QUALITY PROTEIN: Fanconi anemia group D2 protein-like.	Fanconi anemia group C protein-like isoform X1.	0.989
ENSSGRP00000046665	ENSSGRP00000003997	ENSSGRP00000046665	ENSSGRP00000003997	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1 protein-like.	0.997
ENSSGRP00000046665	ENSSGRP00000106720	ENSSGRP00000046665	ENSSGRP00000106720	Bardet-Biedl syndrome 4.	Smoothened homolog.	0.729
ENSSGRP00000076187	ENSSGRP00000003997	ENSSGRP00000076187	ENSSGRP00000003997	Bardet-Biedl syndrome 4 protein-like.	Bardet-Biedl syndrome 1 protein-like.	0.997
ENSSGRP00000076187	ENSSGRP00000106720	ENSSGRP00000076187	ENSSGRP00000106720	Bardet-Biedl syndrome 4 protein-like.	Smoothened homolog.	0.729
ENSSGRP00000106720	Bbs4	ENSSGRP00000106720	ENSSGRP00000076186	Smoothened homolog.	Bardet-Biedl syndrome 4 protein.	0.729
ENSSGRP00000106720	ENSSGRP00000003997	ENSSGRP00000106720	ENSSGRP00000003997	Smoothened homolog.	Bardet-Biedl syndrome 1 protein-like.	0.907
ENSSGRP00000106720	ENSSGRP00000046665	ENSSGRP00000106720	ENSSGRP00000046665	Smoothened homolog.	Bardet-Biedl syndrome 4.	0.729
ENSSGRP00000106720	ENSSGRP00000076187	ENSSGRP00000106720	ENSSGRP00000076187	Smoothened homolog.	Bardet-Biedl syndrome 4 protein-like.	0.729