(37 nodes) Neuromast development network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000054890	E3 ubiquitin-protein ligase ZNRF3 isoform X1. (852 aa)
	LOC107583518	Monoacylglycerol lipase ABHD12. (418 aa)
	LOC107596814	Sphingosine 1-phosphate receptor 2-like. (370 aa)
	lrrc1	Leucine-rich repeat-containing protein 1. (528 aa)
	ENSSGRP00000094528	Scribble planar cell polarity protein. (1755 aa)
	LOC107553896	Wingless-type MMTV integration site family, member 5. (374 aa)
	ENSSGRP00000096325	Abhydrolase domain containing 12. (382 aa)
	LOC107574842	Caveolin-1-like. (279 aa)
	ENSSGRP00000103390	E3 ubiquitin-protein ligase ZNRF3-like. (844 aa)
	ENSSGRP00000108960	Solute carrier family 44 member 4. (565 aa)
	ENSSGRP00000048140	annotation not available (813 aa)
	ENSSGRP00000045452	LLGL scribble cell polarity complex component 2. (897 aa)
	ENSSGRP00000044311	Transmembrane channel-like 2b. (831 aa)
	ENSSGRP00000042478	Vang-like protein 2. (279 aa)
	Vangl2	Vang-like protein 2. (440 aa)
	LOC107600514	R-spondin 3. (316 aa)
	ENSSGRP00000037188	Transmembrane protein 132E. (1031 aa)
	LOC107587933	Sphingosine 1-phosphate receptor 2. (370 aa)
	ENSSGRP00000036219	Mothers against decapentaplegic homolog 1-like. (181 aa)
	ENSSGRP00000036217	annotation not available (113 aa)
	LOC107598364	Neurogenin 1. (208 aa)
	LOC107557662	Transmembrane O-methyltransferase isoform X1. (259 aa)
	llgl2	Lethal(2) giant larvae protein homolog 2 isoform X1. (1029 aa)
	LOC107597704	Leucine-rich repeat-containing protein 1-like. (526 aa)
	LOC107548952	V-type H+-transporting ATPase subunit d. (350 aa)
	LOC107563463	V-type H+-transporting ATPase subunit d. (359 aa)
	LOC107601389	Neurogenic differentiation factor 1-like. (348 aa)
	CAV1	Caveolin 1. (181 aa)
	ENSSGRP00000010007	R-spondin-3-like. (320 aa)
	ENSSGRP00000003802	Scribble planar cell polarity protein. (1807 aa)
	INSM1	INSM transcriptional repressor 1. (400 aa)
	ENSSGRP00000050990	Solute carrier family 44 member 4. (679 aa)
	ENSSGRP00000052150	Neurogenin-1-like. (208 aa)
	LOC107548428	Insulinoma-associated protein 1a. (398 aa)
	ENSSGRP00000054792	Neuronal differentiation 1. (303 aa)
	LOC107572035	Wingless-type MMTV integration site family, member 5. (380 aa)
	LOC107563595	Mothers against decapentaplegic homolog 5 isoform X1. (464 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000003802	ENSSGRP00000042478	ENSSGRP00000003802	ENSSGRP00000042478	Scribble planar cell polarity protein.	Vang-like protein 2.	0.725
ENSSGRP00000003802	Vangl2	ENSSGRP00000003802	ENSSGRP00000042474	Scribble planar cell polarity protein.	Vang-like protein 2.	0.725
ENSSGRP00000010007	ENSSGRP00000054890	ENSSGRP00000010007	ENSSGRP00000054890	R-spondin-3-like.	E3 ubiquitin-protein ligase ZNRF3 isoform X1.	0.984
ENSSGRP00000010007	ENSSGRP00000103390	ENSSGRP00000010007	ENSSGRP00000103390	R-spondin-3-like.	E3 ubiquitin-protein ligase ZNRF3-like.	0.984
ENSSGRP00000036217	ENSSGRP00000036219	ENSSGRP00000036217	ENSSGRP00000036219	annotation not available	Mothers against decapentaplegic homolog 1-like.	0.498
ENSSGRP00000036219	ENSSGRP00000036217	ENSSGRP00000036219	ENSSGRP00000036217	Mothers against decapentaplegic homolog 1-like.	annotation not available	0.498
ENSSGRP00000042478	ENSSGRP00000003802	ENSSGRP00000042478	ENSSGRP00000003802	Vang-like protein 2.	Scribble planar cell polarity protein.	0.725
ENSSGRP00000042478	ENSSGRP00000094528	ENSSGRP00000042478	ENSSGRP00000094528	Vang-like protein 2.	Scribble planar cell polarity protein.	0.725
ENSSGRP00000042478	LOC107553896	ENSSGRP00000042478	ENSSGRP00000050175	Vang-like protein 2.	Wingless-type MMTV integration site family, member 5.	0.755
ENSSGRP00000042478	LOC107572035	ENSSGRP00000042478	ENSSGRP00000050689	Vang-like protein 2.	Wingless-type MMTV integration site family, member 5.	0.766
ENSSGRP00000042478	LOC107597704	ENSSGRP00000042478	ENSSGRP00000029644	Vang-like protein 2.	Leucine-rich repeat-containing protein 1-like.	0.612
ENSSGRP00000042478	lrrc1	ENSSGRP00000042478	ENSSGRP00000091817	Vang-like protein 2.	Leucine-rich repeat-containing protein 1.	0.612
ENSSGRP00000052150	INSM1	ENSSGRP00000052150	ENSSGRP00000000380	Neurogenin-1-like.	INSM transcriptional repressor 1.	0.561
ENSSGRP00000052150	LOC107548428	ENSSGRP00000052150	ENSSGRP00000054029	Neurogenin-1-like.	Insulinoma-associated protein 1a.	0.561
ENSSGRP00000054792	INSM1	ENSSGRP00000054792	ENSSGRP00000000380	Neuronal differentiation 1.	INSM transcriptional repressor 1.	0.477
ENSSGRP00000054792	LOC107548428	ENSSGRP00000054792	ENSSGRP00000054029	Neuronal differentiation 1.	Insulinoma-associated protein 1a.	0.477
ENSSGRP00000054890	ENSSGRP00000010007	ENSSGRP00000054890	ENSSGRP00000010007	E3 ubiquitin-protein ligase ZNRF3 isoform X1.	R-spondin-3-like.	0.984
ENSSGRP00000054890	ENSSGRP00000103390	ENSSGRP00000054890	ENSSGRP00000103390	E3 ubiquitin-protein ligase ZNRF3 isoform X1.	E3 ubiquitin-protein ligase ZNRF3-like.	0.900
ENSSGRP00000054890	LOC107600514	ENSSGRP00000054890	ENSSGRP00000039105	E3 ubiquitin-protein ligase ZNRF3 isoform X1.	R-spondin 3.	0.984
ENSSGRP00000094528	ENSSGRP00000042478	ENSSGRP00000094528	ENSSGRP00000042478	Scribble planar cell polarity protein.	Vang-like protein 2.	0.725