(21 nodes) Positive regulation of calcium-mediated signaling network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107597544	Calcineurin B homologous protein 1-like. (194 aa)
	ENSSGRP00000098275	A-kinase anchor protein 6-like isoform X1. (1092 aa)
	LOC107598100	C-C motif chemokine 8-like. (99 aa)
	ENSSGRP00000092321	Calcium homeostasis endoplasmic reticulum protein-like. (712 aa)
	ENSSGRP00000074248	annotation not available (151 aa)
	ENSSGRP00000071249	annotation not available (1149 aa)
	ENSSGRP00000058284	A-kinase anchor protein 6-like. (1085 aa)
	ENSSGRP00000045128	Signal peptide peptidase-like 3. (388 aa)
	ENSSGRP00000043576	Spleen tyrosine kinase. (526 aa)
	syk	Tyrosine-protein kinase SYK isoform X1. (608 aa)
	ENSSGRP00000038441	Signal peptide peptidase-like 3. (372 aa)
	cherp	Calcium homeostasis endoplasmic reticulum protein. (932 aa)
	ENSSGRP00000034226	Calcium homeostasis endoplasmic reticulum protein-like. (377 aa)
	LOC107582292	Lymphotoxin alpha (TNF superfamily, member 1). (244 aa)
	LOC107548917	Tyrosine-protein kinase ZAP-70-like. (623 aa)
	ENSSGRP00000026016	Tyrosine-protein kinase ZAP-70-like. (327 aa)
	ENSSGRP00000026013	Tyrosine-protein kinase ZAP-70-like. (546 aa)
	LOC107586310	Calcineurin B homologous protein 1-like. (207 aa)
	Lmcd1	LIM and cysteine-rich domains protein 1. (158 aa)
	cib1	Calcium and integrin-binding protein 1. (188 aa)
	ENSSGRP00000006394	annotation not available (243 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000006394	ENSSGRP00000026013	ENSSGRP00000006394	ENSSGRP00000026013	annotation not available	Tyrosine-protein kinase ZAP-70-like.	0.559
ENSSGRP00000006394	ENSSGRP00000026016	ENSSGRP00000006394	ENSSGRP00000026016	annotation not available	Tyrosine-protein kinase ZAP-70-like.	0.559
ENSSGRP00000006394	ENSSGRP00000043576	ENSSGRP00000006394	ENSSGRP00000043576	annotation not available	Spleen tyrosine kinase.	0.559
ENSSGRP00000006394	ENSSGRP00000074248	ENSSGRP00000006394	ENSSGRP00000074248	annotation not available	annotation not available	0.637
ENSSGRP00000006394	LOC107548917	ENSSGRP00000006394	ENSSGRP00000031195	annotation not available	Tyrosine-protein kinase ZAP-70-like.	0.559
ENSSGRP00000006394	LOC107598100	ENSSGRP00000006394	ENSSGRP00000093789	annotation not available	C-C motif chemokine 8-like.	0.753
ENSSGRP00000006394	syk	ENSSGRP00000006394	ENSSGRP00000040643	annotation not available	Tyrosine-protein kinase SYK isoform X1.	0.559
ENSSGRP00000026013	ENSSGRP00000006394	ENSSGRP00000026013	ENSSGRP00000006394	Tyrosine-protein kinase ZAP-70-like.	annotation not available	0.559
ENSSGRP00000026013	LOC107582292	ENSSGRP00000026013	ENSSGRP00000034096	Tyrosine-protein kinase ZAP-70-like.	Lymphotoxin alpha (TNF superfamily, member 1).	0.559
ENSSGRP00000026016	ENSSGRP00000006394	ENSSGRP00000026016	ENSSGRP00000006394	Tyrosine-protein kinase ZAP-70-like.	annotation not available	0.559
ENSSGRP00000026016	LOC107582292	ENSSGRP00000026016	ENSSGRP00000034096	Tyrosine-protein kinase ZAP-70-like.	Lymphotoxin alpha (TNF superfamily, member 1).	0.559
ENSSGRP00000034226	ENSSGRP00000092321	ENSSGRP00000034226	ENSSGRP00000092321	Calcium homeostasis endoplasmic reticulum protein-like.	Calcium homeostasis endoplasmic reticulum protein-like.	0.900
ENSSGRP00000043576	ENSSGRP00000006394	ENSSGRP00000043576	ENSSGRP00000006394	Spleen tyrosine kinase.	annotation not available	0.559
ENSSGRP00000043576	LOC107582292	ENSSGRP00000043576	ENSSGRP00000034096	Spleen tyrosine kinase.	Lymphotoxin alpha (TNF superfamily, member 1).	0.559
ENSSGRP00000074248	ENSSGRP00000006394	ENSSGRP00000074248	ENSSGRP00000006394	annotation not available	annotation not available	0.637
ENSSGRP00000074248	LOC107582292	ENSSGRP00000074248	ENSSGRP00000034096	annotation not available	Lymphotoxin alpha (TNF superfamily, member 1).	0.637
ENSSGRP00000092321	ENSSGRP00000034226	ENSSGRP00000092321	ENSSGRP00000034226	Calcium homeostasis endoplasmic reticulum protein-like.	Calcium homeostasis endoplasmic reticulum protein-like.	0.900
LOC107548917	ENSSGRP00000006394	ENSSGRP00000031195	ENSSGRP00000006394	Tyrosine-protein kinase ZAP-70-like.	annotation not available	0.559
LOC107548917	LOC107582292	ENSSGRP00000031195	ENSSGRP00000034096	Tyrosine-protein kinase ZAP-70-like.	Lymphotoxin alpha (TNF superfamily, member 1).	0.559
LOC107582292	ENSSGRP00000026013	ENSSGRP00000034096	ENSSGRP00000026013	Lymphotoxin alpha (TNF superfamily, member 1).	Tyrosine-protein kinase ZAP-70-like.	0.559