(108 nodes) Cardiac muscle cell differentiation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000055176	Serum response factor-like. (238 aa)
	LOC107602011	Insulin gene enhancer protein isl-1-like isoform X1. (349 aa)
	ENSSGRP00000053827	Fibroblast growth factor 8a. (206 aa)
	ENSSGRP00000053629	annotation not available (281 aa)
	GREM1	Gremlin-1-like. (177 aa)
	ENSSGRP00000052561	Islet1, like. (177 aa)
	maml1	Mastermind-like protein 1. (1021 aa)
	ENSSGRP00000110752	Nebulin-like. (6158 aa)
	Mef2c	MADS-box transcription enhancer factor 2C. (148 aa)
	LOC107583158-2	Uncharacterized LOC107583158. (260 aa)
	LOC107593250	Bone morphogenetic protein 2-like. (411 aa)
	LOC107556463	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1. (415 aa)
	LOC107556942	Hamartin-like isoform X1. (1240 aa)
	ENSSGRP00000101525	NAD-dependent protein deacetylase sirtuin-6-like. (362 aa)
	LOC107602264	Ankyrin repeat and SOCS box protein 2-like isoform X1. (681 aa)
	LOC107602948	Ankyrin repeat and SOCS box protein 2-like. (659 aa)
	ENSSGRP00000099359	Leucine-rich repeat-containing protein 10B-like. (300 aa)
	LOC107584554	Uncharacterized protein LOC107584554. (1623 aa)
	tbx1	T-box transcription factor TBX1 isoform X1. (519 aa)
	LOC107553134	Homeobox protein Nkx-2.5-like. (275 aa)
	ENSSGRP00000096400	Myosin light chain kinase 3. (654 aa)
	LOC107586158	Lysine-specific demethylase 6B-like isoform X1. (1714 aa)
	LOC107582871	Telethonin-like. (179 aa)
	ENSSGRP00000091269	Von Willebrand factor A domain containing 5B2. (969 aa)
	LOC107575816	Leucine-rich repeat-containing protein 10-like. (270 aa)
	ENSSGRP00000089801	Bone morphogenetic protein 4. (193 aa)
	LOC107584839	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial-like. (424 aa)
	Atg5	Autophagy-related protein 5. (253 aa)
	ENSSGRP00000088274	T-box transcription factor TBX5-A-like. (208 aa)
	GREM1-2	Gremlin-1-like. (174 aa)
	ENSSGRP00000086705	Mastermind-like protein 1. (880 aa)
	LOC107559447	Homeobox protein Nkx-2.5-like. (273 aa)
	LOC107588741	Fibroblast growth factor 8-like. (210 aa)
	LOC107568266	Serum response factor-like isoform X1. (285 aa)
	LOC107602081	MADS-box transcription enhancer factor 2C. (372 aa)
	ENSSGRP00000083154	Myocyte-specific enhancer factor 2A-like isoform X1. (92 aa)
	kdm6b	Lysine-specific demethylase 6B. (2020 aa)
	ENSSGRP00000082393	Gremlin 2, DAN family BMP antagonist a. (151 aa)
	LOC107599171	Insulin gene enhancer protein isl-1 isoform X1. (349 aa)
	ENSSGRP00000080319	Cysteine and glycine-rich protein 3-like. (186 aa)
	ENSSGRP00000080271	Myocyte-specific enhancer factor 2A-like. (482 aa)
	LOC107582739	Dynamin-like 120 kDa protein, mitochondrial isoform X1. (1037 aa)
	CSRP3	Cysteine and glycine-rich protein 3-like isoform X1. (190 aa)
	IRX3	Iroquois-class homeodomain protein irx-3-like. (199 aa)
	BMP4	Bone morphogenetic protein 4-like. (400 aa)
	ENSSGRP00000076796	annotation not available (290 aa)
	ENSSGRP00000076285	Sirtuin 6. (350 aa)
	LOC107583498	Gremlin-2-like. (194 aa)
	irx3	Iroquois-class homeodomain protein IRX-3. (454 aa)
	ENSSGRP00000068393	Nebulin. (6113 aa)
	LOC107593523	Cytochrome P450 family 26 subfamily A. (494 aa)
	ENSSGRP00000066462	Alpha-protein kinase 3-like. (200 aa)
	LOC107552491	Heart- and neural crest derivatives-expressed protein 2. (208 aa)
	ENSSGRP00000060007	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (643 aa)
	ENSSGRP00000060002	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (630 aa)
	ENSSGRP00000009428	annotation not available (142 aa)
	LOC107554308	Lysine-specific demethylase 6B-like isoform X1. (1682 aa)
	ENSSGRP00000011628	annotation not available (197 aa)
	ENSSGRP00000014280	Nebulin-related anchoring protein. (1300 aa)
	LOC107587327	Hamartin-like isoform X1. (1138 aa)
	LOC107596578	Cytochrome P450 family 26 subfamily A. (494 aa)
	LOC107583157	Mesoderm posterior protein 2-like. (246 aa)
	LOC107583158	Uncharacterized protein LOC107583158. (260 aa)
	ENSSGRP00000017318	Insulin gene enhancer protein ISL-2A-like isoform X1. (286 aa)
	ENSSGRP00000017557	Caveolin-3-like. (142 aa)
	ENSSGRP00000018198	Serum response factor-like. (238 aa)
	ENSSGRP00000019947	annotation not available (401 aa)
	ENSSGRP00000021657	annotation not available (1244 aa)
	tbx5	T-box transcription factor TBX5. (522 aa)
	ENSSGRP00000022067	Bone morphogenetic protein 2-like. (332 aa)
	ENSSGRP00000022438	Mitogen-activated protein kinase kinase 4a. (367 aa)
	ENSSGRP00000022808	Dual specificity mitogen-activated protein kinase kinase 4-like. (254 aa)
	ENSSGRP00000023709	annotation not available (432 aa)
	LOC107585173	Dynamin-like 120 kDa protein, mitochondrial isoform X1. (1037 aa)
	ENSSGRP00000027530	Leucine-rich repeat-containing protein 10-like. (270 aa)
	LOC107597815	Hamartin-like isoform X1. (1140 aa)
	LOC107566293	Bone morphogenetic protein 2-like. (424 aa)
	Nr2f1	COUP transcription factor 1 isoform X1. (383 aa)
	ENSSGRP00000034618	Autophagy-related protein 5. (163 aa)
	LOC107602542	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial-like. (437 aa)
	LOC107588969	Myocyte-specific enhancer factor 2C-like isoform X1. (492 aa)
	LOC107552890	Bone morphogenetic protein 2-like. (388 aa)
	nrap	Nebulin related anchoring protein. (1710 aa)
	ENSSGRP00000036904	T-box transcription factor 1. (434 aa)
	NR2F1	Nuclear receptor subfamily 2 group F member 1-A isoform X1. (411 aa)
	LOC107601954	Beta-sarcoglycan-like isoform X1. (313 aa)
	LOC107567477	Homeobox protein Nkx-2.5-like. (309 aa)
	LOC107598375	Homeobox protein Nkx-2.5-like. (315 aa)
	LOC107590785	Telethonin-like. (179 aa)
	LOC107551382	Serum response factor-like. (524 aa)
	ENSSGRP00000044449	Heart- and neural crest derivatives-expressed protein 2-like. (208 aa)
	ENSSGRP00000044940	Gremlin-1-like. (168 aa)
	adprhl1	Protein ADP-ribosylarginine hydrolase-like protein 1. (353 aa)
	LOC107595695	Tuberous sclerosis 1. (1239 aa)
	LOC107601595	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1. (384 aa)
	ENSSGRP00000051532	Myocyte enhancer factor 2aa. (457 aa)
	LOC107583239	CAAX prenyl protease 1 homolog. (484 aa)
	ENSSGRP00000056470	Myocyte enhancer factor 2cb. (204 aa)
	bmp2	Bone morphogenetic protein 2. (388 aa)
	LOC107564227	Serine/threonine-protein kinase mTOR. (2552 aa)
	LOC107584208	Protein chibby homolog 1-like. (125 aa)
	LOC107598691	Myosin light chain kinase 3-like isoform X1. (608 aa)
	ENSSGRP00000003135	annotation not available (218 aa)
	LOC107594963	Serine/threonine-protein kinase mTOR-like. (2549 aa)
	ENSSGRP00000004688	annotation not available (132 aa)
	ENSSGRP00000004828	Bone morphogenetic protein 2-like. (346 aa)
	LOC107577119	Bone morphogenetic protein 2-like. (424 aa)
	ENSSGRP00000009164	Insulin gene enhancer protein isl-1-like. (140 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg5	ENSSGRP00000019947	ENSSGRP00000088289	ENSSGRP00000019947	Autophagy-related protein 5.	annotation not available	0.459
Atg5	ENSSGRP00000034618	ENSSGRP00000088289	ENSSGRP00000034618	Autophagy-related protein 5.	Autophagy-related protein 5.	0.900
Atg5	LOC107564227	ENSSGRP00000088289	ENSSGRP00000054966	Autophagy-related protein 5.	Serine/threonine-protein kinase mTOR.	0.632
Atg5	LOC107582739	ENSSGRP00000088289	ENSSGRP00000079925	Autophagy-related protein 5.	Dynamin-like 120 kDa protein, mitochondrial isoform X1.	0.485
Atg5	LOC107585173	ENSSGRP00000088289	ENSSGRP00000023910	Autophagy-related protein 5.	Dynamin-like 120 kDa protein, mitochondrial isoform X1.	0.485
Atg5	LOC107594963	ENSSGRP00000088289	ENSSGRP00000003759	Autophagy-related protein 5.	Serine/threonine-protein kinase mTOR-like.	0.632
BMP4	ENSSGRP00000044940	ENSSGRP00000078686	ENSSGRP00000044940	Bone morphogenetic protein 4-like.	Gremlin-1-like.	0.794
BMP4	ENSSGRP00000053827	ENSSGRP00000078686	ENSSGRP00000053827	Bone morphogenetic protein 4-like.	Fibroblast growth factor 8a.	0.483
BMP4	ENSSGRP00000088274	ENSSGRP00000078686	ENSSGRP00000088274	Bone morphogenetic protein 4-like.	T-box transcription factor TBX5-A-like.	0.460
BMP4	GREM1	ENSSGRP00000078686	ENSSGRP00000052726	Bone morphogenetic protein 4-like.	Gremlin-1-like.	0.749
BMP4	GREM1-2	ENSSGRP00000078686	ENSSGRP00000087686	Bone morphogenetic protein 4-like.	Gremlin-1-like.	0.749
BMP4	LOC107567477	ENSSGRP00000078686	ENSSGRP00000041521	Bone morphogenetic protein 4-like.	Homeobox protein Nkx-2.5-like.	0.452
BMP4	LOC107583498	ENSSGRP00000078686	ENSSGRP00000076202	Bone morphogenetic protein 4-like.	Gremlin-2-like.	0.749
BMP4	LOC107588741	ENSSGRP00000078686	ENSSGRP00000085674	Bone morphogenetic protein 4-like.	Fibroblast growth factor 8-like.	0.483
BMP4	LOC107598375	ENSSGRP00000078686	ENSSGRP00000041746	Bone morphogenetic protein 4-like.	Homeobox protein Nkx-2.5-like.	0.452
BMP4	LOC107599171	ENSSGRP00000078686	ENSSGRP00000081079	Bone morphogenetic protein 4-like.	Insulin gene enhancer protein isl-1 isoform X1.	0.426
BMP4	LOC107602011	ENSSGRP00000078686	ENSSGRP00000054110	Bone morphogenetic protein 4-like.	Insulin gene enhancer protein isl-1-like isoform X1.	0.426
BMP4	tbx5	ENSSGRP00000078686	ENSSGRP00000021910	Bone morphogenetic protein 4-like.	T-box transcription factor TBX5.	0.460
CSRP3	ENSSGRP00000014280	ENSSGRP00000079260	ENSSGRP00000014280	Cysteine and glycine-rich protein 3-like isoform X1.	Nebulin-related anchoring protein.	0.629
CSRP3	ENSSGRP00000017557	ENSSGRP00000079260	ENSSGRP00000017557	Cysteine and glycine-rich protein 3-like isoform X1.	Caveolin-3-like.	0.472