(47 nodes) Hematopoietic stem cell differentiation network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tmem169	X-ray repair cross-complementing protein 5-like. (724 aa)
	ENSSGRP00000055176	Serum response factor-like. (238 aa)
	LOC107558335	Transcriptional regulator Myc-1. (388 aa)
	ENSSGRP00000065860	Homeobox protein MOX-1-like. (209 aa)
	ENSSGRP00000068938	Neurogenic locus notch homolog protein 1-like isoform X1. (2440 aa)
	ENSSGRP00000071108	T-cell acute lymphocytic leukemia 1. (324 aa)
	LOC107562104	ETS oncogene family protein FEV. (235 aa)
	ENSSGRP00000074979	UFM1-specific ligase 1. (708 aa)
	ENSSGRP00000077727	Excision repair cross-complementation group 2. (678 aa)
	LOC107550292	SH2B adapter protein 3-like. (659 aa)
	LOC107587752	R-spondin-1-like. (264 aa)
	LOC107601732	TFIIH basal transcription factor complex helicase XPD subunit. (783 aa)
	LOC107568266	Serum response factor-like isoform X1. (285 aa)
	ENSSGRP00000084565	E3 ubiquitin-protein ligase mib1-like. (1027 aa)
	BATF	Basic leucine zipper ATF-like transcription factor. (112 aa)
	Notch1	Neurogenic locus notch homolog protein 1. (2140 aa)
	ENSSGRP00000092768	E3 ubiquitin-protein ligase mib1 isoform X1. (1003 aa)
	ENSSGRP00000092780	annotation not available (77 aa)
	ENSSGRP00000097825	Adenylate kinase 2, mitochondrial isoform X1. (282 aa)
	ENSSGRP00000098472	Delta-like protein C isoform X1. (678 aa)
	LOC107588322	Platelet-derived growth factor receptor beta-like. (1065 aa)
	LOC107556372	Adenylate kinase 2, mitochondrial-like. (241 aa)
	ENSSGRP00000107375	UFM1-specific ligase 1. (728 aa)
	batf	ATF-like basic leucine zipper transcriptional factor. (124 aa)
	ENSSGRP00000109007	Notch receptor 1b. (2380 aa)
	LOC107589955	Transcriptional regulator Myc-2. (443 aa)
	ENSSGRP00000002215	annotation not available (73 aa)
	ENSSGRP00000003434	Protein jagged-1a. (1244 aa)
	ENSSGRP00000005304	Neurogenic locus notch homolog protein 1-like. (182 aa)
	ENSSGRP00000005391	Homeobox protein MOX-1-like. (109 aa)
	ENSSGRP00000005459	Neurogenic locus notch homolog protein 1-like. (248 aa)
	ENSSGRP00000005880	T-cell acute lymphocytic leukemia protein 1 homolog. (183 aa)
	LOC107597137	R-spondin 1. (264 aa)
	ENSSGRP00000015256	Homeobox protein MOX-1. (234 aa)
	ENSSGRP00000018198	Serum response factor-like. (238 aa)
	ENSSGRP00000021026	Delta-like protein C isoform X1. (671 aa)
	ENSSGRP00000023188	annotation not available (127 aa)
	ENSSGRP00000023709	annotation not available (432 aa)
	ENSSGRP00000026683	annotation not available (1038 aa)
	Dll1	Delta-like protein 1. (749 aa)
	ENSSGRP00000032330	Neuronal PAS domain protein 4 like. (563 aa)
	ENSSGRP00000040476	LOW QUALITY PROTEIN: platelet-derived growth factor receptor beta-like. (1040 aa)
	ENSSGRP00000042456	SH2B adapter protein 3-like. (598 aa)
	LOC107551382	Serum response factor-like. (524 aa)
	LOC107564214	Delta-like protein D. (608 aa)
	ENSSGRP00000046622	ETS oncogene family protein FEV. (235 aa)
	ENSSGRP00000048421	Neurogenic locus notch homolog protein 1. (2408 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BATF	ENSSGRP00000002215	ENSSGRP00000088812	ENSSGRP00000002215	Basic leucine zipper ATF-like transcription factor.	annotation not available	0.484
Dll1	ENSSGRP00000005304	ENSSGRP00000028871	ENSSGRP00000005304	Delta-like protein 1.	Neurogenic locus notch homolog protein 1-like.	0.694
Dll1	ENSSGRP00000005459	ENSSGRP00000028871	ENSSGRP00000005459	Delta-like protein 1.	Neurogenic locus notch homolog protein 1-like.	0.694
Dll1	ENSSGRP00000048421	ENSSGRP00000028871	ENSSGRP00000048421	Delta-like protein 1.	Neurogenic locus notch homolog protein 1.	0.888
Dll1	ENSSGRP00000068938	ENSSGRP00000028871	ENSSGRP00000068938	Delta-like protein 1.	Neurogenic locus notch homolog protein 1-like isoform X1.	0.888
Dll1	ENSSGRP00000084565	ENSSGRP00000028871	ENSSGRP00000084565	Delta-like protein 1.	E3 ubiquitin-protein ligase mib1-like.	0.609
Dll1	ENSSGRP00000092768	ENSSGRP00000028871	ENSSGRP00000092768	Delta-like protein 1.	E3 ubiquitin-protein ligase mib1 isoform X1.	0.609
Dll1	ENSSGRP00000092780	ENSSGRP00000028871	ENSSGRP00000092780	Delta-like protein 1.	annotation not available	0.609
Dll1	ENSSGRP00000109007	ENSSGRP00000028871	ENSSGRP00000109007	Delta-like protein 1.	Notch receptor 1b.	0.694
Dll1	Notch1	ENSSGRP00000028871	ENSSGRP00000091510	Delta-like protein 1.	Neurogenic locus notch homolog protein 1.	0.888
ENSSGRP00000002215	BATF	ENSSGRP00000002215	ENSSGRP00000088812	annotation not available	Basic leucine zipper ATF-like transcription factor.	0.484
ENSSGRP00000003434	ENSSGRP00000005304	ENSSGRP00000003434	ENSSGRP00000005304	Protein jagged-1a.	Neurogenic locus notch homolog protein 1-like.	0.828
ENSSGRP00000003434	ENSSGRP00000005459	ENSSGRP00000003434	ENSSGRP00000005459	Protein jagged-1a.	Neurogenic locus notch homolog protein 1-like.	0.828
ENSSGRP00000003434	ENSSGRP00000048421	ENSSGRP00000003434	ENSSGRP00000048421	Protein jagged-1a.	Neurogenic locus notch homolog protein 1.	0.937
ENSSGRP00000003434	ENSSGRP00000068938	ENSSGRP00000003434	ENSSGRP00000068938	Protein jagged-1a.	Neurogenic locus notch homolog protein 1-like isoform X1.	0.925
ENSSGRP00000003434	ENSSGRP00000084565	ENSSGRP00000003434	ENSSGRP00000084565	Protein jagged-1a.	E3 ubiquitin-protein ligase mib1-like.	0.416
ENSSGRP00000003434	ENSSGRP00000092768	ENSSGRP00000003434	ENSSGRP00000092768	Protein jagged-1a.	E3 ubiquitin-protein ligase mib1 isoform X1.	0.416
ENSSGRP00000003434	ENSSGRP00000092780	ENSSGRP00000003434	ENSSGRP00000092780	Protein jagged-1a.	annotation not available	0.416
ENSSGRP00000003434	ENSSGRP00000109007	ENSSGRP00000003434	ENSSGRP00000109007	Protein jagged-1a.	Notch receptor 1b.	0.795
ENSSGRP00000003434	Notch1	ENSSGRP00000003434	ENSSGRP00000091510	Protein jagged-1a.	Neurogenic locus notch homolog protein 1.	0.937