(37 nodes) Regulation of necroptotic process network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000029960	Receptor-interacting serine-threonine kinase 3. (364 aa)
	ENSSGRP00000029534	Caspase-8-like. (202 aa)
	ENSSGRP00000024758	annotation not available (173 aa)
	ENSSGRP00000017533	Adenine DNA glycosylase-like isoform X1. (196 aa)
	ENSSGRP00000017531	annotation not available (480 aa)
	LOC107573567	RanBP-type and C3HC4-type zinc finger-containing protein 1-like. (510 aa)
	ENSSGRP00000012313	annotation not available (215 aa)
	ENSSGRP00000006151	Caspase-8-like isoform X1. (152 aa)
	ENSSGRP00000005841	CASP8 and FADD-like apoptosis regulator b. (187 aa)
	LOC107582983	Caspase-6-like. (341 aa)
	LOC107570294	CASP8 and FADD-like apoptosis regulator. (494 aa)
	ENSSGRP00000109066	Spermatogenesis-associated protein 2-like. (563 aa)
	LOC107556989	Ubiquitin carboxyl-terminal hydrolase CYLD-like. (772 aa)
	ENSSGRP00000106672	Cylindromatosis (turban tumor syndrome), b. (616 aa)
	ENSSGRP00000088263	Si:dkey-181m9.8. (536 aa)
	ENSSGRP00000087331	Caspase-8-like. (228 aa)
	ENSSGRP00000087301	annotation not available (286 aa)
	ENSSGRP00000086633	CASP8 and FADD-like apoptosis regulator. (221 aa)
	LOC107594801	Poly(ADP-ribose) glycohydrolase ARH3-like. (380 aa)
	rnf31	E3 ubiquitin-protein ligase RNF31. (1055 aa)
	CASP6	Caspase-6-like. (300 aa)
	ENSSGRP00000079686	Ubiquitin carboxyl-terminal hydrolase CYLD-like. (925 aa)
	LOC107559437	FAS-associated death domain protein-like. (192 aa)
	LOC107551493	Ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1. (963 aa)
	LOC107562628	Spermatogenesis-associated protein 2-like. (554 aa)
	ENSSGRP00000059563	Receptor-interacting serine-threonine kinase 3. (332 aa)
	LOC107561543	Poly(ADP-ribose) glycohydrolase ARH3. (381 aa)
	ENSSGRP00000048275	RanBP-type and C3HC4-type zinc finger-containing protein 1-like. (497 aa)
	ENSSGRP00000037392	annotation not available (910 aa)
	ENSSGRP00000034880	CASP8 and FADD-like apoptosis regulator. (475 aa)
	ENSSGRP00000034839	Caspase 10, apoptosis-related cysteine peptidase. (471 aa)
	ENSSGRP00000031485	Caspase-8-like. (140 aa)
	LOC107555418	Caspase-8-like. (324 aa)
	ENSSGRP00000031237	Caspase-8-like. (477 aa)
	ENSSGRP00000030778	Si:dkey-181m9.8. (344 aa)
	ENSSGRP00000030777	Uncharacterized protein LOC107602534. (529 aa)
	ENSSGRP00000029537	annotation not available (218 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP6	ENSSGRP00000006151	ENSSGRP00000082653	ENSSGRP00000006151	Caspase-6-like.	Caspase-8-like isoform X1.	0.598
CASP6	ENSSGRP00000029534	ENSSGRP00000082653	ENSSGRP00000029534	Caspase-6-like.	Caspase-8-like.	0.598
CASP6	ENSSGRP00000029537	ENSSGRP00000082653	ENSSGRP00000029537	Caspase-6-like.	annotation not available	0.598
CASP6	ENSSGRP00000029960	ENSSGRP00000082653	ENSSGRP00000029960	Caspase-6-like.	Receptor-interacting serine-threonine kinase 3.	0.651
CASP6	ENSSGRP00000031237	ENSSGRP00000082653	ENSSGRP00000031237	Caspase-6-like.	Caspase-8-like.	0.958
CASP6	ENSSGRP00000031485	ENSSGRP00000082653	ENSSGRP00000031485	Caspase-6-like.	Caspase-8-like.	0.598
CASP6	ENSSGRP00000034839	ENSSGRP00000082653	ENSSGRP00000034839	Caspase-6-like.	Caspase 10, apoptosis-related cysteine peptidase.	0.598
CASP6	ENSSGRP00000059563	ENSSGRP00000082653	ENSSGRP00000059563	Caspase-6-like.	Receptor-interacting serine-threonine kinase 3.	0.651
CASP6	ENSSGRP00000087301	ENSSGRP00000082653	ENSSGRP00000087301	Caspase-6-like.	annotation not available	0.598
CASP6	ENSSGRP00000087331	ENSSGRP00000082653	ENSSGRP00000087331	Caspase-6-like.	Caspase-8-like.	0.598
CASP6	LOC107555418	ENSSGRP00000082653	ENSSGRP00000031239	Caspase-6-like.	Caspase-8-like.	0.958
CASP6	LOC107559437	ENSSGRP00000082653	ENSSGRP00000074211	Caspase-6-like.	FAS-associated death domain protein-like.	0.696
ENSSGRP00000005841	ENSSGRP00000006151	ENSSGRP00000005841	ENSSGRP00000006151	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like isoform X1.	0.769
ENSSGRP00000005841	ENSSGRP00000029534	ENSSGRP00000005841	ENSSGRP00000029534	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000029537	ENSSGRP00000005841	ENSSGRP00000029537	CASP8 and FADD-like apoptosis regulator b.	annotation not available	0.769
ENSSGRP00000005841	ENSSGRP00000029960	ENSSGRP00000005841	ENSSGRP00000029960	CASP8 and FADD-like apoptosis regulator b.	Receptor-interacting serine-threonine kinase 3.	0.602
ENSSGRP00000005841	ENSSGRP00000031237	ENSSGRP00000005841	ENSSGRP00000031237	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000031485	ENSSGRP00000005841	ENSSGRP00000031485	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000034839	ENSSGRP00000005841	ENSSGRP00000034839	CASP8 and FADD-like apoptosis regulator b.	Caspase 10, apoptosis-related cysteine peptidase.	0.769
ENSSGRP00000005841	ENSSGRP00000059563	ENSSGRP00000005841	ENSSGRP00000059563	CASP8 and FADD-like apoptosis regulator b.	Receptor-interacting serine-threonine kinase 3.	0.602