(52 nodes) Ureteric bud morphogenesis network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000107730	Wilms tumor protein homolog. (397 aa)
	ENSSGRP00000004828	Bone morphogenetic protein 2-like. (346 aa)
	ENSSGRP00000004765	Transmembrane protein 59-like. (99 aa)
	ENSSGRP00000003135	annotation not available (218 aa)
	tmem59l	Transmembrane protein 59-like. (246 aa)
	LOC107587303	Putative fibroblast growth factor 1. (158 aa)
	LOC107585633	Heparan sulfate 2-O-sulfotransferase HS2ST1. (354 aa)
	LOC107582013	Putative fibroblast growth factor 1. (158 aa)
	ENSSGRP00000083705	Growth regulating estrogen receptor binding 1. (1714 aa)
	LOC107570818-2	Beta-catenin-interacting protein 1. (81 aa)
	ENSSGRP00000087559	Integrin-linked kinase. (442 aa)
	ENSSGRP00000087981	annotation not available (122 aa)
	LOC107594824	Protein GREB1-like. (1760 aa)
	LOC107554712	Putative fibroblast growth factor 1. (147 aa)
	ENSSGRP00000089762	Si:dkey-222b8.1. (527 aa)
	ENSSGRP00000089801	Bone morphogenetic protein 4. (193 aa)
	ENSSGRP00000091219	Wilms tumor protein homolog. (392 aa)
	ENSSGRP00000097038	Heparan sulfate 2-O-sulfotransferase 1b. (343 aa)
	ENSSGRP00000098989	Mothers against decapentaplegic homolog 4-like. (169 aa)
	LOC107589844	Heparan sulfate 2-O-sulfotransferase 1-like. (354 aa)
	ENSSGRP00000104891	Mothers against decapentaplegic homolog 4-like. (571 aa)
	epcam	Epithelial cell adhesion molecule. (307 aa)
	LOC107549058	Transcription factor 21-like. (176 aa)
	ENSSGRP00000055936	LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HERC1. (117 aa)
	ENSSGRP00000060047	Transmembrane protein 59-like. (320 aa)
	ENSSGRP00000064080	WT1 transcription factor a. (406 aa)
	LOC107595157	Leucine zipper putative tumor suppressor 2 homolog. (598 aa)
	LOC107557741	Heparan sulfate 2-O-sulfotransferase 1-like. (364 aa)
	ENSSGRP00000068352	Leucine zipper putative tumor suppressor 2 homolog. (439 aa)
	LOC107586479	Epithelial cell adhesion molecule-like. (305 aa)
	LOC107562106	Wingless-type MMTV integration site family, member 6. (355 aa)
	wt1	Wilms tumor protein isoform X1. (415 aa)
	ENSSGRP00000076363	Mothers against decapentaplegic homolog 4-like isoform X1. (573 aa)
	GDNF	Glial cell line-derived neurotrophic factor-like. (235 aa)
	BMP4	Bone morphogenetic protein 4-like. (400 aa)
	Ilk	Integrin-linked protein kinase. (434 aa)
	ENSSGRP00000046628	Wingless-type MMTV integration site family, member 6b. (321 aa)
	LOC107571274	Transcription factor 21. (176 aa)
	LOC107550085	Mothers against decapentaplegic homolog 4-like isoform X1. (571 aa)
	ENSSGRP00000044940	Gremlin-1-like. (168 aa)
	ENSSGRP00000037475	Glial cell line-derived neurotrophic factor-like. (200 aa)
	LOC107570818	Beta-catenin-interacting protein 1 (inhibitor of beta-catenin and Tcf-4). (81 aa)
	ENSSGRP00000029869	SMAD family member 4b. (484 aa)
	LOC107566293	Bone morphogenetic protein 2-like. (424 aa)
	ENSSGRP00000029145	Leucine zipper, putative tumor suppressor family member 3a. (342 aa)
	npnt	Nephronectin isoform X1. (637 aa)
	ENSSGRP00000022575	SMAD family member 4a. (499 aa)
	LOC107574519	Leucine zipper putative tumor suppressor 3-like isoform X1. (761 aa)
	ENSSGRP00000010396	SMAD family member 4b. (464 aa)
	LOC107559658	Mothers against decapentaplegic homolog 4 isoform X1. (550 aa)
	LOC107577119	Bone morphogenetic protein 2-like. (424 aa)
	ENSSGRP00000006642	annotation not available (118 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	ENSSGRP00000010396	ENSSGRP00000078686	ENSSGRP00000010396	Bone morphogenetic protein 4-like.	SMAD family member 4b.	0.649
BMP4	ENSSGRP00000022575	ENSSGRP00000078686	ENSSGRP00000022575	Bone morphogenetic protein 4-like.	SMAD family member 4a.	0.649
BMP4	ENSSGRP00000029869	ENSSGRP00000078686	ENSSGRP00000029869	Bone morphogenetic protein 4-like.	SMAD family member 4b.	0.649
BMP4	ENSSGRP00000044940	ENSSGRP00000078686	ENSSGRP00000044940	Bone morphogenetic protein 4-like.	Gremlin-1-like.	0.794
BMP4	ENSSGRP00000076363	ENSSGRP00000078686	ENSSGRP00000076363	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog 4-like isoform X1.	0.619
BMP4	ENSSGRP00000089762	ENSSGRP00000078686	ENSSGRP00000089762	Bone morphogenetic protein 4-like.	Si:dkey-222b8.1.	0.619
BMP4	ENSSGRP00000098989	ENSSGRP00000078686	ENSSGRP00000098989	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog 4-like.	0.649
BMP4	ENSSGRP00000104891	ENSSGRP00000078686	ENSSGRP00000104891	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog 4-like.	0.619
BMP4	LOC107550085	ENSSGRP00000078686	ENSSGRP00000045624	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog 4-like isoform X1.	0.619
BMP4	LOC107559658	ENSSGRP00000078686	ENSSGRP00000007947	Bone morphogenetic protein 4-like.	Mothers against decapentaplegic homolog 4 isoform X1.	0.649
ENSSGRP00000003135	ENSSGRP00000010396	ENSSGRP00000003135	ENSSGRP00000010396	annotation not available	SMAD family member 4b.	0.649
ENSSGRP00000003135	ENSSGRP00000022575	ENSSGRP00000003135	ENSSGRP00000022575	annotation not available	SMAD family member 4a.	0.649
ENSSGRP00000003135	ENSSGRP00000029869	ENSSGRP00000003135	ENSSGRP00000029869	annotation not available	SMAD family member 4b.	0.649
ENSSGRP00000003135	ENSSGRP00000044940	ENSSGRP00000003135	ENSSGRP00000044940	annotation not available	Gremlin-1-like.	0.437
ENSSGRP00000003135	ENSSGRP00000076363	ENSSGRP00000003135	ENSSGRP00000076363	annotation not available	Mothers against decapentaplegic homolog 4-like isoform X1.	0.619
ENSSGRP00000003135	ENSSGRP00000089762	ENSSGRP00000003135	ENSSGRP00000089762	annotation not available	Si:dkey-222b8.1.	0.619
ENSSGRP00000003135	ENSSGRP00000098989	ENSSGRP00000003135	ENSSGRP00000098989	annotation not available	Mothers against decapentaplegic homolog 4-like.	0.649
ENSSGRP00000003135	ENSSGRP00000104891	ENSSGRP00000003135	ENSSGRP00000104891	annotation not available	Mothers against decapentaplegic homolog 4-like.	0.619
ENSSGRP00000003135	LOC107550085	ENSSGRP00000003135	ENSSGRP00000045624	annotation not available	Mothers against decapentaplegic homolog 4-like isoform X1.	0.619
ENSSGRP00000003135	LOC107559658	ENSSGRP00000003135	ENSSGRP00000007947	annotation not available	Mothers against decapentaplegic homolog 4 isoform X1.	0.649