(23 nodes) Necroptotic process network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107581522	Tumor necrosis factor ligand superfamily member 6-like. (268 aa)
	ENSSGRP00000059563	Receptor-interacting serine-threonine kinase 3. (332 aa)
	LOC107586239	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase. (400 aa)
	ipmk	Inositol polyphosphate multikinase. (375 aa)
	ENSSGRP00000063426	Inositol polyphosphate multikinase-like. (297 aa)
	LOC107551493	Ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1. (963 aa)
	ENSSGRP00000069856	Fas ligand (TNF superfamily, member 6). (292 aa)
	LOC107559437	FAS-associated death domain protein-like. (192 aa)
	LOC107597453	Lymphotoxin alpha (TNF superfamily, member 1). (228 aa)
	LOC107561681	Inositol-tetrakisphosphate 1-kinase-like. (423 aa)
	ENSSGRP00000078429	Inositol polyphosphate multikinase-like. (372 aa)
	ENSSGRP00000079686	Ubiquitin carboxyl-terminal hydrolase CYLD-like. (925 aa)
	ENSSGRP00000000244	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase. (407 aa)
	LOC107554068	Tumor necrosis factor receptor superfamily member 6-like isoform X1. (298 aa)
	LOC107583548	Tumor necrosis factor receptor superfamily member 6-like. (306 aa)
	ENSSGRP00000006394	annotation not available (243 aa)
	ENSSGRP00000023793	Tumor necrosis factor-like. (239 aa)
	ENSSGRP00000029960	Receptor-interacting serine-threonine kinase 3. (364 aa)
	LOC107582292	Lymphotoxin alpha (TNF superfamily, member 1). (244 aa)
	LOC107586822	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase. (236 aa)
	Mlkl	Mixed lineage kinase domain-like protein isoform X1. (468 aa)
	ENSSGRP00000106672	Cylindromatosis (turban tumor syndrome), b. (616 aa)
	LOC107556989	Ubiquitin carboxyl-terminal hydrolase CYLD-like. (772 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000000244	ENSSGRP00000063426	ENSSGRP00000000244	ENSSGRP00000063426	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase.	Inositol polyphosphate multikinase-like.	0.948
ENSSGRP00000000244	ENSSGRP00000078429	ENSSGRP00000000244	ENSSGRP00000078429	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase.	Inositol polyphosphate multikinase-like.	0.948
ENSSGRP00000000244	LOC107586239	ENSSGRP00000000244	ENSSGRP00000060227	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase.	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase.	0.900
ENSSGRP00000000244	LOC107586822	ENSSGRP00000000244	ENSSGRP00000043533	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase.	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase.	0.901
ENSSGRP00000000244	ipmk	ENSSGRP00000000244	ENSSGRP00000060996	Inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase.	Inositol polyphosphate multikinase.	0.950
ENSSGRP00000006394	ENSSGRP00000029960	ENSSGRP00000006394	ENSSGRP00000029960	annotation not available	Receptor-interacting serine-threonine kinase 3.	0.956
ENSSGRP00000006394	ENSSGRP00000059563	ENSSGRP00000006394	ENSSGRP00000059563	annotation not available	Receptor-interacting serine-threonine kinase 3.	0.956
ENSSGRP00000006394	ENSSGRP00000069856	ENSSGRP00000006394	ENSSGRP00000069856	annotation not available	Fas ligand (TNF superfamily, member 6).	0.647
ENSSGRP00000006394	ENSSGRP00000079686	ENSSGRP00000006394	ENSSGRP00000079686	annotation not available	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	0.829
ENSSGRP00000006394	ENSSGRP00000106672	ENSSGRP00000006394	ENSSGRP00000106672	annotation not available	Cylindromatosis (turban tumor syndrome), b.	0.829
ENSSGRP00000006394	LOC107551493	ENSSGRP00000006394	ENSSGRP00000068842	annotation not available	Ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1.	0.829
ENSSGRP00000006394	LOC107554068	ENSSGRP00000006394	ENSSGRP00000001837	annotation not available	Tumor necrosis factor receptor superfamily member 6-like isoform X1.	0.675
ENSSGRP00000006394	LOC107556989	ENSSGRP00000006394	ENSSGRP00000108389	annotation not available	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	0.829
ENSSGRP00000006394	LOC107559437	ENSSGRP00000006394	ENSSGRP00000074211	annotation not available	FAS-associated death domain protein-like.	0.855
ENSSGRP00000006394	LOC107581522	ENSSGRP00000006394	ENSSGRP00000006550	annotation not available	Tumor necrosis factor ligand superfamily member 6-like.	0.647
ENSSGRP00000006394	LOC107583548	ENSSGRP00000006394	ENSSGRP00000005561	annotation not available	Tumor necrosis factor receptor superfamily member 6-like.	0.675
ENSSGRP00000006394	Mlkl	ENSSGRP00000006394	ENSSGRP00000093378	annotation not available	Mixed lineage kinase domain-like protein isoform X1.	0.991
ENSSGRP00000029960	ENSSGRP00000006394	ENSSGRP00000029960	ENSSGRP00000006394	Receptor-interacting serine-threonine kinase 3.	annotation not available	0.956
ENSSGRP00000029960	ENSSGRP00000069856	ENSSGRP00000029960	ENSSGRP00000069856	Receptor-interacting serine-threonine kinase 3.	Fas ligand (TNF superfamily, member 6).	0.535
ENSSGRP00000029960	ENSSGRP00000079686	ENSSGRP00000029960	ENSSGRP00000079686	Receptor-interacting serine-threonine kinase 3.	Ubiquitin carboxyl-terminal hydrolase CYLD-like.	0.584