(32 nodes) Cysteine-type endopeptidase activity involved in apoptotic signaling pathway network (Sinocyclocheilus grahami)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000087301	annotation not available (286 aa)
	ENSSGRP00000002159	annotation not available (384 aa)
	ENSSGRP00000005841	CASP8 and FADD-like apoptosis regulator b. (187 aa)
	ENSSGRP00000006151	Caspase-8-like isoform X1. (152 aa)
	ENSSGRP00000010868	Caspase-8-like. (240 aa)
	ENSSGRP00000011951	PYD and CARD domain containing. (198 aa)
	LOC107592160	Caspase-1-like. (391 aa)
	ENSSGRP00000012313	annotation not available (215 aa)
	ENSSGRP00000018200	Caspase-1-A-like. (386 aa)
	ENSSGRP00000023758	Caspase-1-A-like. (374 aa)
	LOC107593914	Caspase-9-like isoform X1. (436 aa)
	ENSSGRP00000029534	Caspase-8-like. (202 aa)
	ENSSGRP00000029537	annotation not available (218 aa)
	LOC107566313	Caspase-8-like. (350 aa)
	LOC107574341	Caspase-1-like. (452 aa)
	ENSSGRP00000031237	Caspase-8-like. (477 aa)
	LOC107555418	Caspase-8-like. (324 aa)
	ENSSGRP00000031485	Caspase-8-like. (140 aa)
	LOC107571421	Caspase-1-A-like isoform X1. (402 aa)
	ENSSGRP00000034416	Caspase-1-like. (393 aa)
	ENSSGRP00000034418	PYD and CARD domain containing. (201 aa)
	ENSSGRP00000034839	Caspase 10, apoptosis-related cysteine peptidase. (471 aa)
	ENSSGRP00000034880	CASP8 and FADD-like apoptosis regulator. (475 aa)
	LOC107570904	Caspase-1-A-like. (385 aa)
	LOC107570294	CASP8 and FADD-like apoptosis regulator. (494 aa)
	casp9	Caspase-9 isoform X1. (436 aa)
	LOC107597346	Caspase-8-like isoform X1. (383 aa)
	casp2	Caspase-2 isoform X1. (434 aa)
	ENSSGRP00000063046	Caspase-2-like. (409 aa)
	LOC107558420	Caspase-1-like. (455 aa)
	ENSSGRP00000086633	CASP8 and FADD-like apoptosis regulator. (221 aa)
	ENSSGRP00000087331	Caspase-8-like. (228 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000002159	ENSSGRP00000011951	ENSSGRP00000002159	ENSSGRP00000011951	annotation not available	PYD and CARD domain containing.	0.803
ENSSGRP00000002159	ENSSGRP00000034418	ENSSGRP00000002159	ENSSGRP00000034418	annotation not available	PYD and CARD domain containing.	0.803
ENSSGRP00000005841	ENSSGRP00000006151	ENSSGRP00000005841	ENSSGRP00000006151	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like isoform X1.	0.769
ENSSGRP00000005841	ENSSGRP00000010868	ENSSGRP00000005841	ENSSGRP00000010868	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.754
ENSSGRP00000005841	ENSSGRP00000029534	ENSSGRP00000005841	ENSSGRP00000029534	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000029537	ENSSGRP00000005841	ENSSGRP00000029537	CASP8 and FADD-like apoptosis regulator b.	annotation not available	0.769
ENSSGRP00000005841	ENSSGRP00000031237	ENSSGRP00000005841	ENSSGRP00000031237	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000031485	ENSSGRP00000005841	ENSSGRP00000031485	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	ENSSGRP00000034839	ENSSGRP00000005841	ENSSGRP00000034839	CASP8 and FADD-like apoptosis regulator b.	Caspase 10, apoptosis-related cysteine peptidase.	0.769
ENSSGRP00000005841	ENSSGRP00000087301	ENSSGRP00000005841	ENSSGRP00000087301	CASP8 and FADD-like apoptosis regulator b.	annotation not available	0.769
ENSSGRP00000005841	ENSSGRP00000087331	ENSSGRP00000005841	ENSSGRP00000087331	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	LOC107555418	ENSSGRP00000005841	ENSSGRP00000031239	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.769
ENSSGRP00000005841	LOC107566313	ENSSGRP00000005841	ENSSGRP00000029538	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like.	0.754
ENSSGRP00000005841	LOC107597346	ENSSGRP00000005841	ENSSGRP00000039385	CASP8 and FADD-like apoptosis regulator b.	Caspase-8-like isoform X1.	0.754
ENSSGRP00000006151	ENSSGRP00000005841	ENSSGRP00000006151	ENSSGRP00000005841	Caspase-8-like isoform X1.	CASP8 and FADD-like apoptosis regulator b.	0.769
ENSSGRP00000006151	ENSSGRP00000011951	ENSSGRP00000006151	ENSSGRP00000011951	Caspase-8-like isoform X1.	PYD and CARD domain containing.	0.684
ENSSGRP00000006151	ENSSGRP00000012313	ENSSGRP00000006151	ENSSGRP00000012313	Caspase-8-like isoform X1.	annotation not available	0.769
ENSSGRP00000006151	ENSSGRP00000034418	ENSSGRP00000006151	ENSSGRP00000034418	Caspase-8-like isoform X1.	PYD and CARD domain containing.	0.684
ENSSGRP00000006151	ENSSGRP00000034880	ENSSGRP00000006151	ENSSGRP00000034880	Caspase-8-like isoform X1.	CASP8 and FADD-like apoptosis regulator.	0.769
ENSSGRP00000006151	ENSSGRP00000063046	ENSSGRP00000006151	ENSSGRP00000063046	Caspase-8-like isoform X1.	Caspase-2-like.	0.460