(30 nodes) Positive regulation of signaling receptor activity network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000102835	ADAM metallopeptidase domain 17a. (847 aa)
	LOC107595520	Neutrophil cytosolic factor 1-like. (423 aa)
	ENSSGRP00000002570	Proheparin-binding EGF-like growth factor. (209 aa)
	ENSSGRP00000004635	annotation not available (124 aa)
	LOC107559691	Endothelin-1-like. (226 aa)
	LOC107552826	RWD domain-containing protein 1-like. (240 aa)
	LOC107551139	Voltage-dependent calcium channel gamma-2 subunit-like. (240 aa)
	LOC107557065	Proheparin-binding EGF-like growth factor. (222 aa)
	ENSSGRP00000026203	Disintegrin and metalloproteinase domain-containing protein 17-like. (745 aa)
	ENSSGRP00000026381	Voltage-dependent calcium channel gamma-2 subunit. (326 aa)
	ENSSGRP00000044940	Gremlin-1-like. (168 aa)
	LOC107559299	Proheparin-binding EGF-like growth factor. (222 aa)
	LOC107590185	Interleukin-10-like. (179 aa)
	ENSSGRP00000052659	Serine/threonine-protein kinase PINK1, mitochondrial-like. (355 aa)
	GREM1	Gremlin-1-like. (177 aa)
	LOC107549102	Disintegrin and metalloproteinase domain-containing protein 17-like isoform X1. (842 aa)
	ENSSGRP00000054531	Probetacellulin-like isoform X1. (168 aa)
	ENSSGRP00000065440	Calcium channel, voltage-dependent, gamma subunit 3b. (296 aa)
	LOC107555104	Voltage-dependent calcium channel gamma-2 subunit-like. (316 aa)
	ENSSGRP00000072183	Epigen-like isoform X1. (142 aa)
	LOC107583498	Gremlin-2-like. (194 aa)
	LOC107587125	Proheparin-binding EGF-like growth factor. (228 aa)
	LOC107587776	RWD domain-containing protein 1-like. (240 aa)
	ENSSGRP00000082393	Gremlin 2, DAN family BMP antagonist a. (151 aa)
	LOC107601850	Disintegrin and metalloproteinase domain-containing protein 17-like isoform X1. (842 aa)
	GREM1-2	Gremlin-1-like. (174 aa)
	LOC107551767	Endothelin-1-like. (189 aa)
	ENSSGRP00000089103	Voltage-dependent calcium channel gamma-2 subunit-like. (300 aa)
	LOC107555708	Interleukin-10-like. (179 aa)
	LOC107565989	Epigen-like isoform X1. (155 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000002570	ENSSGRP00000004635	ENSSGRP00000002570	ENSSGRP00000004635	Proheparin-binding EGF-like growth factor.	annotation not available	0.720
ENSSGRP00000002570	ENSSGRP00000054531	ENSSGRP00000002570	ENSSGRP00000054531	Proheparin-binding EGF-like growth factor.	Probetacellulin-like isoform X1.	0.720
ENSSGRP00000002570	ENSSGRP00000072183	ENSSGRP00000002570	ENSSGRP00000072183	Proheparin-binding EGF-like growth factor.	Epigen-like isoform X1.	0.679
ENSSGRP00000002570	LOC107565989	ENSSGRP00000002570	ENSSGRP00000111764	Proheparin-binding EGF-like growth factor.	Epigen-like isoform X1.	0.679
ENSSGRP00000004635	ENSSGRP00000002570	ENSSGRP00000004635	ENSSGRP00000002570	annotation not available	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000004635	ENSSGRP00000072183	ENSSGRP00000004635	ENSSGRP00000072183	annotation not available	Epigen-like isoform X1.	0.807
ENSSGRP00000004635	LOC107557065	ENSSGRP00000004635	ENSSGRP00000024670	annotation not available	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000004635	LOC107559299	ENSSGRP00000004635	ENSSGRP00000045603	annotation not available	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000004635	LOC107565989	ENSSGRP00000004635	ENSSGRP00000111764	annotation not available	Epigen-like isoform X1.	0.807
ENSSGRP00000004635	LOC107587125	ENSSGRP00000004635	ENSSGRP00000081946	annotation not available	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000026203	LOC107549102	ENSSGRP00000026203	ENSSGRP00000053473	Disintegrin and metalloproteinase domain-containing protein 17-like.	Disintegrin and metalloproteinase domain-containing protein 17-like isoform X1.	0.902
ENSSGRP00000026203	LOC107601850	ENSSGRP00000026203	ENSSGRP00000086805	Disintegrin and metalloproteinase domain-containing protein 17-like.	Disintegrin and metalloproteinase domain-containing protein 17-like isoform X1.	0.902
ENSSGRP00000054531	ENSSGRP00000002570	ENSSGRP00000054531	ENSSGRP00000002570	Probetacellulin-like isoform X1.	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000054531	ENSSGRP00000072183	ENSSGRP00000054531	ENSSGRP00000072183	Probetacellulin-like isoform X1.	Epigen-like isoform X1.	0.807
ENSSGRP00000054531	LOC107557065	ENSSGRP00000054531	ENSSGRP00000024670	Probetacellulin-like isoform X1.	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000054531	LOC107559299	ENSSGRP00000054531	ENSSGRP00000045603	Probetacellulin-like isoform X1.	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000054531	LOC107565989	ENSSGRP00000054531	ENSSGRP00000111764	Probetacellulin-like isoform X1.	Epigen-like isoform X1.	0.807
ENSSGRP00000054531	LOC107587125	ENSSGRP00000054531	ENSSGRP00000081946	Probetacellulin-like isoform X1.	Proheparin-binding EGF-like growth factor.	0.720
ENSSGRP00000072183	ENSSGRP00000002570	ENSSGRP00000072183	ENSSGRP00000002570	Epigen-like isoform X1.	Proheparin-binding EGF-like growth factor.	0.679
ENSSGRP00000072183	ENSSGRP00000004635	ENSSGRP00000072183	ENSSGRP00000004635	Epigen-like isoform X1.	annotation not available	0.807