(25 nodes) Positive regulation of stem cell differentiation network (Sinocyclocheilus grahami)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107597543	Transcription elongation factor SPT5 isoform X1. (1077 aa)
	LOC107590035	Transcription factor SOX5/6/13 (SOX group D). (825 aa)
	LOC107586479	Epithelial cell adhesion molecule-like. (305 aa)
	LOC107587062	Transcription factor SOX5/6/13 (SOX group D). (771 aa)
	ENSSGRP00000056823	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (855 aa)
	ENSSGRP00000059853	SRY-box transcription factor 6. (757 aa)
	LOC107592929	RNA-binding protein 24. (229 aa)
	LOC107565300	RNA-binding protein 24-A-like isoform X1. (223 aa)
	ENSSGRP00000066673	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46. (911 aa)
	LOC107589143	Transforming growth factor beta-2-like. (414 aa)
	ENSSGRP00000004521	annotation not available (73 aa)
	tgfb2	Transforming growth factor beta-2. (411 aa)
	LOC107598937	Transforming growth factor beta-2-like. (411 aa)
	LOC107598375	Homeobox protein Nkx-2.5-like. (315 aa)
	LOC107567477	Homeobox protein Nkx-2.5-like. (309 aa)
	ENSSGRP00000040243	Transforming growth factor beta-2-like. (444 aa)
	ENSSGRP00000037570	SRY-box transcription factor 6. (818 aa)
	LOC107583845	Cleavage and polyadenylation specificity factor subunit 5-like. (194 aa)
	LOC107586261	Transcription elongation factor SPT5-like isoform X1. (1080 aa)
	ENSSGRP00000101525	NAD-dependent protein deacetylase sirtuin-6-like. (362 aa)
	epcam	Epithelial cell adhesion molecule. (307 aa)
	pwp1	Periodic tryptophan protein 1 homolog. (487 aa)
	ENSSGRP00000097029	Cleavage and polyadenylation specificity factor subunit 5. (213 aa)
	LOC107591968	RNA-binding protein 24-like. (229 aa)
	ENSSGRP00000076285	Sirtuin 6. (350 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000037570	LOC107587062	ENSSGRP00000037570	ENSSGRP00000047464	SRY-box transcription factor 6.	Transcription factor SOX5/6/13 (SOX group D).	0.799
ENSSGRP00000037570	LOC107590035	ENSSGRP00000037570	ENSSGRP00000072917	SRY-box transcription factor 6.	Transcription factor SOX5/6/13 (SOX group D).	0.800
ENSSGRP00000056823	ENSSGRP00000066673	ENSSGRP00000056823	ENSSGRP00000066673	DEAH (Asp-Glu-Ala-His) box polypeptide 36.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	0.589
ENSSGRP00000059853	LOC107587062	ENSSGRP00000059853	ENSSGRP00000047464	SRY-box transcription factor 6.	Transcription factor SOX5/6/13 (SOX group D).	0.800
ENSSGRP00000059853	LOC107590035	ENSSGRP00000059853	ENSSGRP00000072917	SRY-box transcription factor 6.	Transcription factor SOX5/6/13 (SOX group D).	0.800
ENSSGRP00000066673	ENSSGRP00000056823	ENSSGRP00000066673	ENSSGRP00000056823	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	DEAH (Asp-Glu-Ala-His) box polypeptide 36.	0.589
ENSSGRP00000097029	LOC107583845	ENSSGRP00000097029	ENSSGRP00000033211	Cleavage and polyadenylation specificity factor subunit 5.	Cleavage and polyadenylation specificity factor subunit 5-like.	0.900
LOC107583845	ENSSGRP00000097029	ENSSGRP00000033211	ENSSGRP00000097029	Cleavage and polyadenylation specificity factor subunit 5-like.	Cleavage and polyadenylation specificity factor subunit 5.	0.900
LOC107587062	ENSSGRP00000037570	ENSSGRP00000047464	ENSSGRP00000037570	Transcription factor SOX5/6/13 (SOX group D).	SRY-box transcription factor 6.	0.799
LOC107587062	ENSSGRP00000059853	ENSSGRP00000047464	ENSSGRP00000059853	Transcription factor SOX5/6/13 (SOX group D).	SRY-box transcription factor 6.	0.800
LOC107590035	ENSSGRP00000037570	ENSSGRP00000072917	ENSSGRP00000037570	Transcription factor SOX5/6/13 (SOX group D).	SRY-box transcription factor 6.	0.800
LOC107590035	ENSSGRP00000059853	ENSSGRP00000072917	ENSSGRP00000059853	Transcription factor SOX5/6/13 (SOX group D).	SRY-box transcription factor 6.	0.800