(43 nodes) Negative regulation of double-strand break repair network (Sinocyclocheilus grahami)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000035698	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169-like. (118 aa)
	LOC107600464	Tumor suppressor p53-binding protein 1-like. (1634 aa)
	LOC107557052	Ubiquitin thioesterase protein OTUB1. (140 aa)
	Rnf169	E3 ubiquitin-protein ligase RNF169. (132 aa)
	ENSSGRP00000011443	Cyclic GMP-AMP synthase-like isoform X1. (434 aa)
	LOC107579146	E3 ubiquitin-protein ligase UBR5-like. (302 aa)
	rmi2	RecQ-mediated genome instability protein 2. (149 aa)
	ogg1	N-glycosylase/DNA lyase. (396 aa)
	ENSSGRP00000000830	High mobility group AT-hook 2. (84 aa)
	LOC107594694	DNA helicase B-like isoform X1. (1195 aa)
	LOC107573342	Uncharacterized protein LOC107573342. (251 aa)
	Smchd1	Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (1925 aa)
	LOC107548808	Uncharacterized protein CXorf57-like. (802 aa)
	ENSSGRP00000101205	Protein FAM35A-like. (257 aa)
	ENSSGRP00000101202	annotation not available (397 aa)
	recql5	ATP-dependent DNA helicase Q5. (970 aa)
	LOC107588177	Ubiquitin thioesterase protein OTUB1. (271 aa)
	ENSSGRP00000092521	F-box DNA helicase 1. (948 aa)
	LOC107562237	Ubiquitin thioesterase OTUB1-like isoform X1. (266 aa)
	LOC107558426	Uncharacterized protein CXorf57-like. (804 aa)
	Trip12	E3 ubiquitin-protein ligase TRIP12. (1466 aa)
	ENSSGRP00000084766	E3 ubiquitin-protein ligase TRIP12-like. (1801 aa)
	ENSSGRP00000051038	FA complementation group B. (733 aa)
	ENSSGRP00000050083	F-box protein, helicase, 18. (861 aa)
	LOC107587130	DNA helicase B-like isoform X1. (1399 aa)
	ENSSGRP00000086417	annotation not available (99 aa)
	ENSSGRP00000089850	annotation not available (238 aa)
	ENSSGRP00000089852	annotation not available (119 aa)
	Aunip	Aurora kinase A and ninein-interacting protein. (320 aa)
	LOC107588615	DNA excision repair protein ERCC-6-like. (1395 aa)
	ENSSGRP00000049789	annotation not available (141 aa)
	ENSSGRP00000047873	PARP1 binding protein. (535 aa)
	ENSSGRP00000046014	Cyclic GMP-AMP synthase-like. (376 aa)
	ENSSGRP00000045226	E3 ubiquitin-protein ligase EDD1. (2413 aa)
	LOC107560665	Ubiquitin thioesterase protein OTUB1. (267 aa)
	Rif1	Telomere-associated protein RIF1. (2189 aa)
	ENSSGRP00000058109	Structural maintenance of chromosomes flexible hinge domain-containing protein 1-like. (1750 aa)
	ENSSGRP00000104050	Tumor protein p53 binding protein, 1. (1687 aa)
	ENSSGRP00000110678	Replication timing regulatory factor 1. (2339 aa)
	ENSSGRP00000074253	PARP1 binding protein. (478 aa)
	ENSSGRP00000037943	RecQ mediated genome instability 2. (108 aa)
	LOC107597314	Uncharacterized protein CXorf57 homolog. (556 aa)
	ENSSGRP00000036259	Ubiquitin protein ligase E3 component n-recognin 5. (2237 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000011443	ENSSGRP00000046014	ENSSGRP00000011443	ENSSGRP00000046014	Cyclic GMP-AMP synthase-like isoform X1.	Cyclic GMP-AMP synthase-like.	0.900
ENSSGRP00000035698	ENSSGRP00000084766	ENSSGRP00000035698	ENSSGRP00000084766	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169-like.	E3 ubiquitin-protein ligase TRIP12-like.	0.628
ENSSGRP00000035698	ENSSGRP00000104050	ENSSGRP00000035698	ENSSGRP00000104050	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169-like.	Tumor protein p53 binding protein, 1.	0.862
ENSSGRP00000035698	ENSSGRP00000110678	ENSSGRP00000035698	ENSSGRP00000110678	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169-like.	Replication timing regulatory factor 1.	0.407
ENSSGRP00000035698	LOC107600464	ENSSGRP00000035698	ENSSGRP00000026454	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169-like.	Tumor suppressor p53-binding protein 1-like.	0.862
ENSSGRP00000035698	Rif1	ENSSGRP00000035698	ENSSGRP00000067914	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169-like.	Telomere-associated protein RIF1.	0.407
ENSSGRP00000035698	Trip12	ENSSGRP00000035698	ENSSGRP00000078053	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169-like.	E3 ubiquitin-protein ligase TRIP12.	0.628
ENSSGRP00000036259	ENSSGRP00000084766	ENSSGRP00000036259	ENSSGRP00000084766	Ubiquitin protein ligase E3 component n-recognin 5.	E3 ubiquitin-protein ligase TRIP12-like.	0.968
ENSSGRP00000036259	ENSSGRP00000104050	ENSSGRP00000036259	ENSSGRP00000104050	Ubiquitin protein ligase E3 component n-recognin 5.	Tumor protein p53 binding protein, 1.	0.515
ENSSGRP00000036259	LOC107579146	ENSSGRP00000036259	ENSSGRP00000009574	Ubiquitin protein ligase E3 component n-recognin 5.	E3 ubiquitin-protein ligase UBR5-like.	0.418
ENSSGRP00000036259	LOC107600464	ENSSGRP00000036259	ENSSGRP00000026454	Ubiquitin protein ligase E3 component n-recognin 5.	Tumor suppressor p53-binding protein 1-like.	0.515
ENSSGRP00000036259	Trip12	ENSSGRP00000036259	ENSSGRP00000078053	Ubiquitin protein ligase E3 component n-recognin 5.	E3 ubiquitin-protein ligase TRIP12.	0.968
ENSSGRP00000037943	recql5	ENSSGRP00000037943	ENSSGRP00000098326	RecQ mediated genome instability 2.	ATP-dependent DNA helicase Q5.	0.916
ENSSGRP00000045226	ENSSGRP00000084766	ENSSGRP00000045226	ENSSGRP00000084766	E3 ubiquitin-protein ligase EDD1.	E3 ubiquitin-protein ligase TRIP12-like.	0.968
ENSSGRP00000045226	ENSSGRP00000104050	ENSSGRP00000045226	ENSSGRP00000104050	E3 ubiquitin-protein ligase EDD1.	Tumor protein p53 binding protein, 1.	0.515
ENSSGRP00000045226	LOC107600464	ENSSGRP00000045226	ENSSGRP00000026454	E3 ubiquitin-protein ligase EDD1.	Tumor suppressor p53-binding protein 1-like.	0.515
ENSSGRP00000045226	Trip12	ENSSGRP00000045226	ENSSGRP00000078053	E3 ubiquitin-protein ligase EDD1.	E3 ubiquitin-protein ligase TRIP12.	0.968
ENSSGRP00000046014	ENSSGRP00000011443	ENSSGRP00000046014	ENSSGRP00000011443	Cyclic GMP-AMP synthase-like.	Cyclic GMP-AMP synthase-like isoform X1.	0.900
ENSSGRP00000047873	ENSSGRP00000084766	ENSSGRP00000047873	ENSSGRP00000084766	PARP1 binding protein.	E3 ubiquitin-protein ligase TRIP12-like.	0.655
ENSSGRP00000047873	Trip12	ENSSGRP00000047873	ENSSGRP00000078053	PARP1 binding protein.	E3 ubiquitin-protein ligase TRIP12.	0.655