(10 nodes) Mre11 complex network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000110723	annotation not available (56 aa)
	Rbbp8	DNA endonuclease RBBP8 isoform X1. (641 aa)
	ENSSGRP00000038462	Checkpoint kinase 2. (471 aa)
	mre11	Double-strand break repair protein MRE11A isoform X1. (717 aa)
	LOC107595095	Nibrin-like isoform X1. (842 aa)
	ENSSGRP00000079966	Checkpoint kinase 2. (436 aa)
	ENSSGRP00000086521	RAD50 homolog, double strand break repair protein. (1178 aa)
	Atm	Serine-protein kinase ATM. (2839 aa)
	rad50	DNA repair protein RAD50 isoform X1. (1312 aa)
	LOC107582084	Nibrin-like. (858 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	ENSSGRP00000038462	ENSSGRP00000093119	ENSSGRP00000038462	Serine-protein kinase ATM.	Checkpoint kinase 2.	0.985
Atm	ENSSGRP00000079966	ENSSGRP00000093119	ENSSGRP00000079966	Serine-protein kinase ATM.	Checkpoint kinase 2.	0.985
Atm	ENSSGRP00000086521	ENSSGRP00000093119	ENSSGRP00000086521	Serine-protein kinase ATM.	RAD50 homolog, double strand break repair protein.	0.988
Atm	ENSSGRP00000110723	ENSSGRP00000093119	ENSSGRP00000110723	Serine-protein kinase ATM.	annotation not available	0.988
Atm	LOC107582084	ENSSGRP00000093119	ENSSGRP00000015571	Serine-protein kinase ATM.	Nibrin-like.	0.999
Atm	LOC107595095	ENSSGRP00000093119	ENSSGRP00000079047	Serine-protein kinase ATM.	Nibrin-like isoform X1.	0.999
Atm	Rbbp8	ENSSGRP00000093119	ENSSGRP00000020506	Serine-protein kinase ATM.	DNA endonuclease RBBP8 isoform X1.	0.982
Atm	mre11	ENSSGRP00000093119	ENSSGRP00000051217	Serine-protein kinase ATM.	Double-strand break repair protein MRE11A isoform X1.	0.999
Atm	rad50	ENSSGRP00000093119	ENSSGRP00000110721	Serine-protein kinase ATM.	DNA repair protein RAD50 isoform X1.	0.998
ENSSGRP00000038462	Atm	ENSSGRP00000038462	ENSSGRP00000093119	Checkpoint kinase 2.	Serine-protein kinase ATM.	0.985
ENSSGRP00000038462	ENSSGRP00000086521	ENSSGRP00000038462	ENSSGRP00000086521	Checkpoint kinase 2.	RAD50 homolog, double strand break repair protein.	0.743
ENSSGRP00000038462	ENSSGRP00000110723	ENSSGRP00000038462	ENSSGRP00000110723	Checkpoint kinase 2.	annotation not available	0.743
ENSSGRP00000038462	LOC107582084	ENSSGRP00000038462	ENSSGRP00000015571	Checkpoint kinase 2.	Nibrin-like.	0.878
ENSSGRP00000038462	LOC107595095	ENSSGRP00000038462	ENSSGRP00000079047	Checkpoint kinase 2.	Nibrin-like isoform X1.	0.878
ENSSGRP00000038462	Rbbp8	ENSSGRP00000038462	ENSSGRP00000020506	Checkpoint kinase 2.	DNA endonuclease RBBP8 isoform X1.	0.648
ENSSGRP00000038462	mre11	ENSSGRP00000038462	ENSSGRP00000051217	Checkpoint kinase 2.	Double-strand break repair protein MRE11A isoform X1.	0.880
ENSSGRP00000038462	rad50	ENSSGRP00000038462	ENSSGRP00000110721	Checkpoint kinase 2.	DNA repair protein RAD50 isoform X1.	0.743
ENSSGRP00000079966	Atm	ENSSGRP00000079966	ENSSGRP00000093119	Checkpoint kinase 2.	Serine-protein kinase ATM.	0.985
ENSSGRP00000079966	ENSSGRP00000086521	ENSSGRP00000079966	ENSSGRP00000086521	Checkpoint kinase 2.	RAD50 homolog, double strand break repair protein.	0.743
ENSSGRP00000079966	ENSSGRP00000110723	ENSSGRP00000079966	ENSSGRP00000110723	Checkpoint kinase 2.	annotation not available	0.743