(36 nodes) MLL1/2 complex network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107562763	L-myc proto-oncogene protein. (404 aa)
	LOC107591376	Chromodomain-helicase-DNA-binding protein 8 isoform X1. (2561 aa)
	LOC107596045	Testis-expressed sequence 10 protein homolog. (935 aa)
	HCFC2	Host cell factor 2-like. (322 aa)
	ENSSGRP00000099096	MAX dimerization protein MGA a. (2103 aa)
	LOC107584272	L-myc proto-oncogene protein. (401 aa)
	Kmt2b	Histone-lysine N-methyltransferase 2B isoform X1. (3268 aa)
	ENSSGRP00000021574	Menin-like. (428 aa)
	LOC107557917	Chromodomain-helicase-DNA-binding protein 8-like isoform X1. (2559 aa)
	LOC107567817	E3 ubiquitin-protein ligase RING2-A-like. (352 aa)
	ENSSGRP00000006125	annotation not available (174 aa)
	ENSSGRP00000005803	annotation not available (158 aa)
	RING1	E3 ubiquitin-protein ligase RING2-A-like. (353 aa)
	ENSSGRP00000001777	[histone H3]-lysine4 N-trimethyltransferase MLL4. (3760 aa)
	LOC107558056	Max dimerization protein 3-like. (199 aa)
	LOC107602050	Max protein. (156 aa)
	LOC107593696	Testis-expressed sequence 10 protein homolog. (1021 aa)
	LOC107599038	Host cell factor 1-like isoform X1. (1863 aa)
	ENSSGRP00000054387	Uncharacterized protein LOC107549105 isoform X1. (317 aa)
	LOC107592226	Host cell factor 2-like isoform X1. (718 aa)
	max	Protein max isoform X1. (165 aa)
	LOC107564705	E3 ubiquitin-protein ligase RING2 isoform X1. (360 aa)
	LOC107552212	Host cell factor 1-like isoform X1. (2024 aa)
	LOC107550994	Max dimerization protein 3. (199 aa)
	LOC107589914	E3 ubiquitin-protein ligase RING2-like. (234 aa)
	ENSSGRP00000064945	Host cell factor C1b. (1910 aa)
	ENSSGRP00000061667	MAX dimerization protein MGA a. (2312 aa)
	ENSSGRP00000061424	[histone H3]-lysine4 N-trimethyltransferase MLL4. (2967 aa)
	LOC107593807	Proline-, glutamic acid- and leucine-rich protein 1-like. (1213 aa)
	Men1	LOW QUALITY PROTEIN: menin. (598 aa)
	ENSSGRP00000075699	annotation not available (3751 aa)
	LOC107561933	Proline-, glutamic acid- and leucine-rich protein 1-like. (1219 aa)
	ENSSGRP00000076850	annotation not available (3988 aa)
	LOC107563734	Host cell factor 1-like. (1635 aa)
	ENSSGRP00000109883	[histone H3]-lysine4 N-trimethyltransferase MLL4. (2852 aa)
	ENSSGRP00000082306	Uncharacterized protein LOC107602581. (192 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000001777	ENSSGRP00000021574	ENSSGRP00000001777	ENSSGRP00000021574	[histone H3]-lysine4 N-trimethyltransferase MLL4.	Menin-like.	0.809
ENSSGRP00000001777	ENSSGRP00000064945	ENSSGRP00000001777	ENSSGRP00000064945	[histone H3]-lysine4 N-trimethyltransferase MLL4.	Host cell factor C1b.	0.407
ENSSGRP00000001777	HCFC2	ENSSGRP00000001777	ENSSGRP00000087879	[histone H3]-lysine4 N-trimethyltransferase MLL4.	Host cell factor 2-like.	0.407
ENSSGRP00000001777	LOC107552212	ENSSGRP00000001777	ENSSGRP00000036836	[histone H3]-lysine4 N-trimethyltransferase MLL4.	Host cell factor 1-like isoform X1.	0.407
ENSSGRP00000001777	LOC107563734	ENSSGRP00000001777	ENSSGRP00000107406	[histone H3]-lysine4 N-trimethyltransferase MLL4.	Host cell factor 1-like.	0.407
ENSSGRP00000001777	LOC107592226	ENSSGRP00000001777	ENSSGRP00000053504	[histone H3]-lysine4 N-trimethyltransferase MLL4.	Host cell factor 2-like isoform X1.	0.407
ENSSGRP00000001777	LOC107599038	ENSSGRP00000001777	ENSSGRP00000055796	[histone H3]-lysine4 N-trimethyltransferase MLL4.	Host cell factor 1-like isoform X1.	0.407
ENSSGRP00000001777	Men1	ENSSGRP00000001777	ENSSGRP00000075281	[histone H3]-lysine4 N-trimethyltransferase MLL4.	LOW QUALITY PROTEIN: menin.	0.809
ENSSGRP00000005803	ENSSGRP00000006125	ENSSGRP00000005803	ENSSGRP00000006125	annotation not available	annotation not available	0.813
ENSSGRP00000005803	ENSSGRP00000054387	ENSSGRP00000005803	ENSSGRP00000054387	annotation not available	Uncharacterized protein LOC107549105 isoform X1.	0.813
ENSSGRP00000005803	ENSSGRP00000082306	ENSSGRP00000005803	ENSSGRP00000082306	annotation not available	Uncharacterized protein LOC107602581.	0.813
ENSSGRP00000005803	LOC107564705	ENSSGRP00000005803	ENSSGRP00000039017	annotation not available	E3 ubiquitin-protein ligase RING2 isoform X1.	0.600
ENSSGRP00000005803	LOC107567817	ENSSGRP00000005803	ENSSGRP00000007264	annotation not available	E3 ubiquitin-protein ligase RING2-A-like.	0.600
ENSSGRP00000005803	LOC107589914	ENSSGRP00000005803	ENSSGRP00000106825	annotation not available	E3 ubiquitin-protein ligase RING2-like.	0.600
ENSSGRP00000005803	LOC107602050	ENSSGRP00000005803	ENSSGRP00000099177	annotation not available	Max protein.	0.908
ENSSGRP00000005803	RING1	ENSSGRP00000005803	ENSSGRP00000004888	annotation not available	E3 ubiquitin-protein ligase RING2-A-like.	0.600
ENSSGRP00000005803	max	ENSSGRP00000005803	ENSSGRP00000052417	annotation not available	Protein max isoform X1.	0.908
ENSSGRP00000006125	ENSSGRP00000005803	ENSSGRP00000006125	ENSSGRP00000005803	annotation not available	annotation not available	0.813
ENSSGRP00000006125	ENSSGRP00000061667	ENSSGRP00000006125	ENSSGRP00000061667	annotation not available	MAX dimerization protein MGA a.	0.813
ENSSGRP00000006125	ENSSGRP00000099096	ENSSGRP00000006125	ENSSGRP00000099096	annotation not available	MAX dimerization protein MGA a.	0.813