(40 nodes) Glutamatergic synapse network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000074461	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa. (753 aa)
	LOC107564117	Pro-neuregulin-1, membrane-bound isoform-like. (691 aa)
	ENSSGRP00000024394	Leucine-rich repeat transmembrane neuronal protein 4-like. (587 aa)
	LRRTM4	Leucine-rich repeat transmembrane neuronal protein 4-like isoform X1. (599 aa)
	clstn3	Calsyntenin 3. (945 aa)
	ENSSGRP00000032422	D(4) dopamine receptor-like. (349 aa)
	ENSSGRP00000035642	Glutamate receptor interacting protein 2a. (1015 aa)
	NPTX1	Neuronal pentraxin-1-like. (424 aa)
	ENSSGRP00000040670	Neuregulin 2b. (571 aa)
	ENSSGRP00000044091	LOW QUALITY PROTEIN: calsyntenin-3-like. (300 aa)
	LOC107551439	D(4) dopamine receptor-like. (373 aa)
	LOC107560524	Leucine-rich repeat transmembrane neuronal protein 4-like isoform X1. (635 aa)
	LOC107594214	Neuronal pentraxin-2-like isoform X1. (421 aa)
	ENSSGRP00000064646	Glutamate receptor interacting protein 2a. (980 aa)
	ENSSGRP00000064888	Proline-rich transmembrane protein 2-like. (134 aa)
	ENSSGRP00000070407	Pro-neuregulin-2, membrane-bound isoform-like. (701 aa)
	ENSSGRP00000070509	Pro-neuregulin-2, membrane-bound isoform-like isoform X1. (568 aa)
	ENSSGRP00000072297	Discs, large (Drosophila) homolog-associated protein 3. (943 aa)
	LOC107591880	X-linked interleukin-1 receptor accessory protein-like 2 isoform X1. (681 aa)
	ENSSGRP00000078976	D(4) dopamine receptor-like. (393 aa)
	LOC107557292	D(4) dopamine receptor-like. (418 aa)
	nptx1	Neuronal pentraxin-1 isoform X1. (423 aa)
	LOC107597572	Cell adhesion molecule 1-like. (417 aa)
	ENSSGRP00000090386	Proline-rich transmembrane protein 2. (120 aa)
	ENSSGRP00000091781	Cell adhesion molecule 1a. (378 aa)
	ENSSGRP00000097636	Neuronal pentraxin 2a. (395 aa)
	LOC107561186	D(4) dopamine receptor-like isoform X1. (374 aa)
	ENSSGRP00000103605	Cell adhesion molecule 1-like isoform X1. (431 aa)
	LOC107552650	Semaphorin-3F-like. (767 aa)
	ENSSGRP00000001478	Semaphorin-3F-like isoform X1. (786 aa)
	ENSSGRP00000003378	Neuronal pentraxin-1-like. (447 aa)
	LOC107575152	Pro-neuregulin-1, membrane-bound isoform-like isoform X1. (683 aa)
	LOC107582575	Cell adhesion molecule 1-like isoform X1. (413 aa)
	ENSSGRP00000010587	Glutamate receptor-interacting protein 2-like. (877 aa)
	ENSSGRP00000012812	Neuronal pentraxin-2-like. (433 aa)
	ENSSGRP00000013243	Neuronal pentraxin IIb. (378 aa)
	LOC107600352	D(4) dopamine receptor-like. (384 aa)
	LOC107575741	semaphorin-3F-like. (806 aa)
	ENSSGRP00000023047	annotation not available (639 aa)
	LOC107557058	Pro-neuregulin-2, membrane-bound isoform-like isoform X1. (803 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000040670	LOC107564117	ENSSGRP00000040670	ENSSGRP00000024285	Neuregulin 2b.	Pro-neuregulin-1, membrane-bound isoform-like.	0.664
ENSSGRP00000040670	LOC107575152	ENSSGRP00000040670	ENSSGRP00000008698	Neuregulin 2b.	Pro-neuregulin-1, membrane-bound isoform-like isoform X1.	0.525
ENSSGRP00000070407	ENSSGRP00000070509	ENSSGRP00000070407	ENSSGRP00000070509	Pro-neuregulin-2, membrane-bound isoform-like.	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	0.903
ENSSGRP00000070407	LOC107557058	ENSSGRP00000070407	ENSSGRP00000024060	Pro-neuregulin-2, membrane-bound isoform-like.	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	0.903
ENSSGRP00000070407	LOC107564117	ENSSGRP00000070407	ENSSGRP00000024285	Pro-neuregulin-2, membrane-bound isoform-like.	Pro-neuregulin-1, membrane-bound isoform-like.	0.639
ENSSGRP00000070407	LOC107575152	ENSSGRP00000070407	ENSSGRP00000008698	Pro-neuregulin-2, membrane-bound isoform-like.	Pro-neuregulin-1, membrane-bound isoform-like isoform X1.	0.525
ENSSGRP00000070509	ENSSGRP00000070407	ENSSGRP00000070509	ENSSGRP00000070407	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	Pro-neuregulin-2, membrane-bound isoform-like.	0.903
ENSSGRP00000070509	LOC107557058	ENSSGRP00000070509	ENSSGRP00000024060	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	0.900
ENSSGRP00000103605	LOC107582575	ENSSGRP00000103605	ENSSGRP00000009704	Cell adhesion molecule 1-like isoform X1.	Cell adhesion molecule 1-like isoform X1.	0.901
LOC107557058	ENSSGRP00000070407	ENSSGRP00000024060	ENSSGRP00000070407	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	Pro-neuregulin-2, membrane-bound isoform-like.	0.903
LOC107557058	ENSSGRP00000070509	ENSSGRP00000024060	ENSSGRP00000070509	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	Pro-neuregulin-2, membrane-bound isoform-like isoform X1.	0.900
LOC107564117	ENSSGRP00000040670	ENSSGRP00000024285	ENSSGRP00000040670	Pro-neuregulin-1, membrane-bound isoform-like.	Neuregulin 2b.	0.664
LOC107564117	ENSSGRP00000070407	ENSSGRP00000024285	ENSSGRP00000070407	Pro-neuregulin-1, membrane-bound isoform-like.	Pro-neuregulin-2, membrane-bound isoform-like.	0.639
LOC107575152	ENSSGRP00000040670	ENSSGRP00000008698	ENSSGRP00000040670	Pro-neuregulin-1, membrane-bound isoform-like isoform X1.	Neuregulin 2b.	0.525
LOC107575152	ENSSGRP00000070407	ENSSGRP00000008698	ENSSGRP00000070407	Pro-neuregulin-1, membrane-bound isoform-like isoform X1.	Pro-neuregulin-2, membrane-bound isoform-like.	0.525
LOC107582575	ENSSGRP00000103605	ENSSGRP00000009704	ENSSGRP00000103605	Cell adhesion molecule 1-like isoform X1.	Cell adhesion molecule 1-like isoform X1.	0.901