(122 nodes) p53-Independent DNA Damage Response network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000007343	annotation not available (160 aa)
	LOC107589994	Proteasome activator complex subunit 1-like. (257 aa)
	LOC107590443	26S proteasome non-ATPase regulatory subunit 11A-like. (237 aa)
	LOC107587164	26S proteasome regulatory subunit T1. (433 aa)
	ENSSGRP00000106221	annotation not available (223 aa)
	LOC107556413	Proteasome subunit alpha type-2. (242 aa)
	LOC107584569	Proteasome subunit beta type-7-like. (286 aa)
	LOC107551845	Proteasome activator complex subunit 2-like. (244 aa)
	ENSSGRP00000104004	Proteasome 20S subunit alpha 6a. (263 aa)
	ENSSGRP00000103292	Proteasome 26S subunit, ATPase 3. (374 aa)
	LOC107563735-2	26S proteasome non-ATPase regulatory subunit 14. (310 aa)
	ENSSGRP00000102551	Proteasome inhibitor PI31 subunit-like. (216 aa)
	Psma3	Proteasome subunit alpha type-3. (127 aa)
	Psmd6	26S proteasome non-ATPase regulatory subunit 6. (466 aa)
	ENSSGRP00000098300	26S proteasome non-ATPase regulatory subunit 1-like. (986 aa)
	LOC107574207	KxDL motif-containing protein 1. (196 aa)
	LOC107586579	26S protease regulatory subunit 4 isoform X1. (440 aa)
	ENSSGRP00000097927	LOW QUALITY PROTEIN: proteasome activator complex subunit 4A-like. (1794 aa)
	ENSSGRP00000097878	Proteasome 26S subunit, non-ATPase 10. (185 aa)
	ENSSGRP00000097497	Checkpoint kinase 1. (411 aa)
	ENSSGRP00000095953	Proteasome subunit alpha type-2-like. (239 aa)
	LOC107591978	Proteasome subunit beta type-2-like. (199 aa)
	LOC107585698	26S proteasome non-ATPase regulatory subunit 5-like. (505 aa)
	ENSSGRP00000089091	Polyubiquitin-B-like isoform X1. (307 aa)
	LOC107549856	Proteasome subunit beta type-8-like. (272 aa)
	ENSSGRP00000088643	Proteasome 20S subunit beta 12. (163 aa)
	LOC107549857	Proteasome subunit beta type-9-like. (229 aa)
	LOC107561039	Proteasome subunit alpha type-7-like. (225 aa)
	LOC107565570	26S proteasome non-ATPase regulatory subunit 4-like. (383 aa)
	ENSSGRP00000087245	Proteasome 20S subunit beta 5. (160 aa)
	ENSSGRP00000087243	annotation not available (311 aa)
	LOC107562288	Proteasome subunit alpha type-4-like. (261 aa)
	ENSSGRP00000084763	Proteasome subunit beta type-4-like isoform X1. (291 aa)
	PSMB3	Proteasome subunit beta type-3. (205 aa)
	psmc3	26S proteasome regulatory subunit T5. (431 aa)
	LOC107563735	26S proteasome non-ATPase regulatory subunit 14. (311 aa)
	LOC107567735-2	ubiquitin-40S ribosomal protein S27a. (156 aa)
	LOC107582747	Proteasome activator complex subunit 3-like isoform X1. (256 aa)
	ENSSGRP00000079966	Checkpoint kinase 2. (436 aa)
	LOC107582453	Proteasome subunit alpha type-5-like. (173 aa)
	LOC107597861	Proteasome subunit alpha type-6 isoform X1. (269 aa)
	LOC107556770	Proteasome activator complex subunit 2-like. (244 aa)
	LOC107560014	Proteasome subunit alpha type-4. (261 aa)
	ENSSGRP00000066810	Proteasome 26S subunit, ATPase 5. (371 aa)
	ENSSGRP00000066180	Proteasome 26S subunit, non-ATPase 4b. (366 aa)
	psmd13	26S proteasome non-ATPase regulatory subunit 13. (380 aa)
	ENSSGRP00000065177	Proteasome 20S subunit beta 11b. (365 aa)
	LOC107599594	26S proteasome non-ATPase regulatory subunit 4-like. (372 aa)
	LOC107601249	26S proteasome non-ATPase regulatory subunit 11A. (429 aa)
	LOC107596848	Proteasome inhibitor PI31 subunit-like. (185 aa)
	LOC107592948	Proteasome subunit beta type-2-like. (207 aa)
	LOC107596690	26S proteasome non-ATPase regulatory subunit 4-like. (378 aa)
	psmd9	26S proteasome non-ATPase regulatory subunit 9 isoform X1. (210 aa)
	LOC107572146	Proteasome subunit alpha type-7. (251 aa)
	LOC107589641	Proteasome subunit alpha type-6-like. (246 aa)
	ENSSGRP00000061741	Proteasome subunit alpha type-3. (208 aa)
	LOC107554985	26S proteasome non-ATPase regulatory subunit 8-like. (267 aa)
	LOC107563209	Proteasome subunit beta type-7-like. (281 aa)
	LOC107585378	Proteasome subunit beta type-7-like. (290 aa)
	LOC107589657	26S protease regulatory subunit 4-like. (410 aa)
	LOC107566641	Proteasome subunit beta type-7-like. (278 aa)
	LOC107566642	Proteasome subunit beta type-6-B like protein isoform X1. (217 aa)
	ENSSGRP00000054316	Proteasome subunit beta type-9-like. (121 aa)
	LOC107553010	26S proteasome non-ATPase regulatory subunit 7. (328 aa)
	PSMB1	Proteasome subunit beta type-1-A-like. (241 aa)
	ENSSGRP00000048330	Proteasome 26S subunit, non-ATPase 6. (254 aa)
	ENSSGRP00000047626	Proteasome activator complex subunit 4B isoform X1. (1834 aa)
	ENSSGRP00000045202	Proteasome 26S subunit, ATPase 5. (233 aa)
	LOC107549540	26S protease regulatory subunit 10B. (396 aa)
	LOC107565228	Proteasome subunit beta type-7-like. (276 aa)
	ENSSGRP00000038462	Checkpoint kinase 2. (471 aa)
	LOC107570970	26S proteasome non-ATPase regulatory subunit 3-like. (507 aa)
	LOC107599401	26S proteasome non-ATPase regulatory subunit 5-like. (505 aa)
	LOC107597712	Proteasome subunit beta type-1-A. (238 aa)
	ENSSGRP00000035319	26S proteasome non-ATPase regulatory subunit 1 isoform X1. (981 aa)
	Psmc4	26S proteasome regulatory subunit T3. (418 aa)
	psmd12	26S proteasome non-ATPase regulatory subunit 12 isoform X1. (476 aa)
	LOC107573823	26S proteasome non-ATPase regulatory subunit 3-like. (527 aa)
	ENSSGRP00000032367	Proteasome subunit beta type-3-like. (96 aa)
	ENSSGRP00000030473	Polyubiquitin-C isoform X1. (685 aa)
	ENSSGRP00000027836	26S proteasome non-ATPase regulatory subunit 11B-like. (407 aa)
	LOC107574275	Proteasome subunit beta type-8-like. (276 aa)
	ENSSGRP00000027660	annotation not available (277 aa)
	ENSSGRP00000027365	annotation not available (224 aa)
	LOC107551636	Serine/threonine-protein kinase Chk1-like. (492 aa)
	psma5	Proteasome subunit alpha type-5. (241 aa)
	LOC107558100	Proteasome subunit beta type-5-like. (269 aa)
	LOC107559243	Proteasome subunit beta type-11-like. (390 aa)
	ENSSGRP00000021595	Proteasome activator complex subunit 1-like isoform X1. (257 aa)
	ENSSGRP00000020665	annotation not available (133 aa)
	psmd10	26S proteasome non-ATPase regulatory subunit 10. (228 aa)
	psma1	Proteasome subunit alpha type-1. (262 aa)
	ENSSGRP00000016970	Proteasome 26S subunit, ATPase 2. (387 aa)
	ENSSGRP00000016799	Proteasome subunit alpha type-1-like. (237 aa)
	LOC107582103	26S protease regulatory subunit 10B-like. (389 aa)
	LOC107552743	Proteasome activator complex subunit 3. (164 aa)
	ENSSGRP00000015048	Proteasome activator complex subunit 4A isoform X1. (1840 aa)
	LOC107584693	26S proteasome non-ATPase regulatory subunit 7. (328 aa)
	LOC107578527	Proteasome subunit alpha type-6-like. (153 aa)
	LOC107568948	26S proteasome non-ATPase regulatory subunit 11B. (517 aa)
	ENSSGRP00000011977	26S proteasome non-ATPase regulatory subunit 13-like. (81 aa)
	ENSSGRP00000011941	26S protease regulatory subunit 6B-like. (381 aa)
	LOC107554342	Proteasome subunit beta type-8-like. (267 aa)
	LOC107554343	Proteasome subunit beta type-7-like. (266 aa)
	ENSSGRP00000010041	annotation not available (226 aa)
	ENSSGRP00000009876	26S proteasome non-ATPase regulatory subunit 11A-like. (309 aa)
	CDC25B	M-phase inducer phosphatase 1-like. (564 aa)
	LOC107581524	26S protease regulatory subunit 4-like. (440 aa)
	ENSSGRP00000006586	annotation not available (75 aa)
	ENSSGRP00000006470	annotation not available (77 aa)
	PSMB6	Proteasome subunit beta type-6. (236 aa)
	ENSSGRP00000005160	Proteasome subunit alpha type-6-like. (139 aa)
	ENSSGRP00000004833	annotation not available (161 aa)
	LOC107580536	26S proteasome non-ATPase regulatory subunit 13-like. (204 aa)
	LOC107565104	26S proteasome non-ATPase regulatory subunit 8-like. (267 aa)
	ENSSGRP00000002471	26S proteasome non-ATPase regulatory subunit 9-like. (126 aa)
	LOC107567735	Ubiquitin-small subunit ribosomal protein S27Ae. (156 aa)
	LOC107569449	26S proteasome non-ATPase regulatory subunit 12-like. (392 aa)
	ENSSGRP00000001434	Proteasome activator subunit 4b. (1790 aa)
	ENSSGRP00000001309	Proteasome subunit beta type-4-like. (260 aa)
	LOC107572211	Proteasome subunit alpha type-6-like. (246 aa)
	LOC107582534	M-phase inducer phosphatase 1-like. (595 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC25B	ENSSGRP00000001434	ENSSGRP00000008820	ENSSGRP00000001434	M-phase inducer phosphatase 1-like.	Proteasome activator subunit 4b.	0.427
CDC25B	ENSSGRP00000004833	ENSSGRP00000008820	ENSSGRP00000004833	M-phase inducer phosphatase 1-like.	annotation not available	0.514
CDC25B	ENSSGRP00000010041	ENSSGRP00000008820	ENSSGRP00000010041	M-phase inducer phosphatase 1-like.	annotation not available	0.476
CDC25B	ENSSGRP00000011977	ENSSGRP00000008820	ENSSGRP00000011977	M-phase inducer phosphatase 1-like.	26S proteasome non-ATPase regulatory subunit 13-like.	0.499
CDC25B	ENSSGRP00000015048	ENSSGRP00000008820	ENSSGRP00000015048	M-phase inducer phosphatase 1-like.	Proteasome activator complex subunit 4A isoform X1.	0.427
CDC25B	ENSSGRP00000016970	ENSSGRP00000008820	ENSSGRP00000016970	M-phase inducer phosphatase 1-like.	Proteasome 26S subunit, ATPase 2.	0.527
CDC25B	ENSSGRP00000021595	ENSSGRP00000008820	ENSSGRP00000021595	M-phase inducer phosphatase 1-like.	Proteasome activator complex subunit 1-like isoform X1.	0.456
CDC25B	ENSSGRP00000030473	ENSSGRP00000008820	ENSSGRP00000030473	M-phase inducer phosphatase 1-like.	Polyubiquitin-C isoform X1.	0.629
CDC25B	ENSSGRP00000038462	ENSSGRP00000008820	ENSSGRP00000038462	M-phase inducer phosphatase 1-like.	Checkpoint kinase 2.	0.938
CDC25B	ENSSGRP00000045202	ENSSGRP00000008820	ENSSGRP00000045202	M-phase inducer phosphatase 1-like.	Proteasome 26S subunit, ATPase 5.	0.536
CDC25B	ENSSGRP00000047626	ENSSGRP00000008820	ENSSGRP00000047626	M-phase inducer phosphatase 1-like.	Proteasome activator complex subunit 4B isoform X1.	0.427
CDC25B	ENSSGRP00000048330	ENSSGRP00000008820	ENSSGRP00000048330	M-phase inducer phosphatase 1-like.	Proteasome 26S subunit, non-ATPase 6.	0.553
CDC25B	ENSSGRP00000066810	ENSSGRP00000008820	ENSSGRP00000066810	M-phase inducer phosphatase 1-like.	Proteasome 26S subunit, ATPase 5.	0.536
CDC25B	ENSSGRP00000079966	ENSSGRP00000008820	ENSSGRP00000079966	M-phase inducer phosphatase 1-like.	Checkpoint kinase 2.	0.938
CDC25B	ENSSGRP00000089091	ENSSGRP00000008820	ENSSGRP00000089091	M-phase inducer phosphatase 1-like.	Polyubiquitin-B-like isoform X1.	0.629
CDC25B	ENSSGRP00000097497	ENSSGRP00000008820	ENSSGRP00000097497	M-phase inducer phosphatase 1-like.	Checkpoint kinase 1.	0.968
CDC25B	ENSSGRP00000097927	ENSSGRP00000008820	ENSSGRP00000097927	M-phase inducer phosphatase 1-like.	LOW QUALITY PROTEIN: proteasome activator complex subunit 4A-like.	0.427
CDC25B	ENSSGRP00000102551	ENSSGRP00000008820	ENSSGRP00000102551	M-phase inducer phosphatase 1-like.	Proteasome inhibitor PI31 subunit-like.	0.471
CDC25B	ENSSGRP00000103292	ENSSGRP00000008820	ENSSGRP00000103292	M-phase inducer phosphatase 1-like.	Proteasome 26S subunit, ATPase 3.	0.528
CDC25B	LOC107551636	ENSSGRP00000008820	ENSSGRP00000026867	M-phase inducer phosphatase 1-like.	Serine/threonine-protein kinase Chk1-like.	0.996