(26 nodes) Death domain network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107595685	Tumor necrosis factor receptor superfamily member 10A/B. (437 aa)
	irak1	Interleukin-1 receptor-associated kinase 1 isoform X1. (704 aa)
	LOC107593958	Uncharacterized protein LOC107593958 isoform X1. (226 aa)
	LOC107593391	Tumor necrosis factor receptor superfamily member 1A-like isoform X1. (391 aa)
	LOC107594999	Tumor necrosis factor receptor superfamily member 10A-like isoform X1. (418 aa)
	ENSSGRP00000002578	Interleukin-1 receptor-associated kinase 3-like. (388 aa)
	LOC107553893	CASP2 and RIPK1 domain containing adaptor with death domain. (201 aa)
	LOC107590265	CASP2 and RIPK1 domain containing adaptor with death domain. (201 aa)
	ENSSGRP00000064951	Interleukin-1 receptor-associated kinase 1. (659 aa)
	ENSSGRP00000061344	Ankyrin repeat and death domain-containing protein 1A-like isoform X1. (488 aa)
	myd88	Myeloid differentiation primary response protein MyD88. (284 aa)
	ENSSGRP00000057067	Tumor necrosis factor receptor superfamily member 1A-like. (388 aa)
	LOC107583532	Ectodysplasin-A receptor-associated adapter protein-like isoform X1. (222 aa)
	LOC107553365	Ectodysplasin-A receptor-associated adapter protein-like. (222 aa)
	ENSSGRP00000000744	Hematopoietic death receptor. (202 aa)
	ENSSGRP00000000804	Interleukin-1 receptor-associated kinase 3. (564 aa)
	ENSSGRP00000053634	P53-induced death domain protein 1. (747 aa)
	Ankdd1a	Ankyrin repeat and death domain-containing protein 1A isoform X1. (490 aa)
	LOC107584943	Myeloid differentiation primary response protein MyD88-like. (284 aa)
	LOC107550806	Tumor necrosis factor receptor superfamily member 1A-like. (395 aa)
	ENSSGRP00000104840	THO complex subunit 1-like. (86 aa)
	ENSSGRP00000099423	P53-induced death domain protein 1. (905 aa)
	LOC107563912	Tumor necrosis factor receptor superfamily member 6-like. (435 aa)
	LOC107553479	Tumor necrosis factor receptor superfamily member 21-like. (654 aa)
	LOC107560558	Tumor necrosis factor receptor superfamily member 16-like isoform X1. (433 aa)
	ENSSGRP00000065143	Ankyrin-1-like. (1516 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000000744	LOC107563912	ENSSGRP00000000744	ENSSGRP00000104634	Hematopoietic death receptor.	Tumor necrosis factor receptor superfamily member 6-like.	0.799
ENSSGRP00000000744	LOC107595685	ENSSGRP00000000744	ENSSGRP00000047859	Hematopoietic death receptor.	Tumor necrosis factor receptor superfamily member 10A/B.	0.798
ENSSGRP00000000804	ENSSGRP00000064951	ENSSGRP00000000804	ENSSGRP00000064951	Interleukin-1 receptor-associated kinase 3.	Interleukin-1 receptor-associated kinase 1.	0.876
ENSSGRP00000000804	LOC107584943	ENSSGRP00000000804	ENSSGRP00000082576	Interleukin-1 receptor-associated kinase 3.	Myeloid differentiation primary response protein MyD88-like.	0.823
ENSSGRP00000000804	irak1	ENSSGRP00000000804	ENSSGRP00000036935	Interleukin-1 receptor-associated kinase 3.	Interleukin-1 receptor-associated kinase 1 isoform X1.	0.884
ENSSGRP00000000804	myd88	ENSSGRP00000000804	ENSSGRP00000057314	Interleukin-1 receptor-associated kinase 3.	Myeloid differentiation primary response protein MyD88.	0.823
ENSSGRP00000002578	ENSSGRP00000064951	ENSSGRP00000002578	ENSSGRP00000064951	Interleukin-1 receptor-associated kinase 3-like.	Interleukin-1 receptor-associated kinase 1.	0.876
ENSSGRP00000002578	LOC107584943	ENSSGRP00000002578	ENSSGRP00000082576	Interleukin-1 receptor-associated kinase 3-like.	Myeloid differentiation primary response protein MyD88-like.	0.823
ENSSGRP00000002578	irak1	ENSSGRP00000002578	ENSSGRP00000036935	Interleukin-1 receptor-associated kinase 3-like.	Interleukin-1 receptor-associated kinase 1 isoform X1.	0.882
ENSSGRP00000002578	myd88	ENSSGRP00000002578	ENSSGRP00000057314	Interleukin-1 receptor-associated kinase 3-like.	Myeloid differentiation primary response protein MyD88.	0.823
ENSSGRP00000053634	LOC107553893	ENSSGRP00000053634	ENSSGRP00000050163	P53-induced death domain protein 1.	CASP2 and RIPK1 domain containing adaptor with death domain.	0.615
ENSSGRP00000053634	LOC107584943	ENSSGRP00000053634	ENSSGRP00000082576	P53-induced death domain protein 1.	Myeloid differentiation primary response protein MyD88-like.	0.449
ENSSGRP00000053634	LOC107590265	ENSSGRP00000053634	ENSSGRP00000075891	P53-induced death domain protein 1.	CASP2 and RIPK1 domain containing adaptor with death domain.	0.615
ENSSGRP00000053634	myd88	ENSSGRP00000053634	ENSSGRP00000057314	P53-induced death domain protein 1.	Myeloid differentiation primary response protein MyD88.	0.449
ENSSGRP00000057067	LOC107550806	ENSSGRP00000057067	ENSSGRP00000111843	Tumor necrosis factor receptor superfamily member 1A-like.	Tumor necrosis factor receptor superfamily member 1A-like.	0.901
ENSSGRP00000057067	LOC107553479	ENSSGRP00000057067	ENSSGRP00000067467	Tumor necrosis factor receptor superfamily member 1A-like.	Tumor necrosis factor receptor superfamily member 21-like.	0.572
ENSSGRP00000057067	LOC107563912	ENSSGRP00000057067	ENSSGRP00000104634	Tumor necrosis factor receptor superfamily member 1A-like.	Tumor necrosis factor receptor superfamily member 6-like.	0.560
ENSSGRP00000057067	LOC107584943	ENSSGRP00000057067	ENSSGRP00000082576	Tumor necrosis factor receptor superfamily member 1A-like.	Myeloid differentiation primary response protein MyD88-like.	0.543
ENSSGRP00000057067	LOC107593391	ENSSGRP00000057067	ENSSGRP00000030523	Tumor necrosis factor receptor superfamily member 1A-like.	Tumor necrosis factor receptor superfamily member 1A-like isoform X1.	0.915
ENSSGRP00000057067	LOC107595685	ENSSGRP00000057067	ENSSGRP00000047859	Tumor necrosis factor receptor superfamily member 1A-like.	Tumor necrosis factor receptor superfamily member 10A/B.	0.560