(17 nodes) Sir2 family network (Sinocyclocheilus grahami)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSGRP00000076285	Sirtuin 6. (350 aa)
	ENSSGRP00000006120	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like. (224 aa)
	ENSSGRP00000013288	Sirtuin 7. (383 aa)
	ENSSGRP00000013593	NAD-dependent protein deacetylase sirtuin-3-like. (368 aa)
	LOC107562394	NAD-dependent protein deacetylase sirtuin-1-like. (642 aa)
	LOC107561440	NAD-dependent protein deacetylase sirtuin-3-like isoform X1. (363 aa)
	ENSSGRP00000055782	Sirtuin 7. (396 aa)
	LOC107568197	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial-like. (309 aa)
	LOC107553976	NAD-dependent protein deacetylase sirtuin-3-like. (380 aa)
	sirt2	NAD-dependent protein deacetylase sirtuin-2 isoform X1. (379 aa)
	ENSSGRP00000082870	Si:dkey-103i16.6. (231 aa)
	ENSSGRP00000082878	Si:dkey-103i16.6. (323 aa)
	ENSSGRP00000101525	NAD-dependent protein deacetylase sirtuin-6-like. (362 aa)
	LOC107565065	NAD-dependent protein deacetylase sirtuin-1-like isoform X1. (501 aa)
	ENSSGRP00000104985	annotation not available (146 aa)
	LOC107581456	NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1. (306 aa)
	ENSSGRP00000112702	annotation not available (281 aa)

Your Current Organism:

Sinocyclocheilus grahami

NCBI taxonomy Id: 75366
Other names: S. grahami

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSGRP00000006120	ENSSGRP00000013288	ENSSGRP00000006120	ENSSGRP00000013288	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Sirtuin 7.	0.628
ENSSGRP00000006120	ENSSGRP00000013593	ENSSGRP00000006120	ENSSGRP00000013593	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein deacetylase sirtuin-3-like.	0.541
ENSSGRP00000006120	ENSSGRP00000055782	ENSSGRP00000006120	ENSSGRP00000055782	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Sirtuin 7.	0.625
ENSSGRP00000006120	ENSSGRP00000076285	ENSSGRP00000006120	ENSSGRP00000076285	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Sirtuin 6.	0.718
ENSSGRP00000006120	ENSSGRP00000082870	ENSSGRP00000006120	ENSSGRP00000082870	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Si:dkey-103i16.6.	0.459
ENSSGRP00000006120	ENSSGRP00000082878	ENSSGRP00000006120	ENSSGRP00000082878	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	Si:dkey-103i16.6.	0.459
ENSSGRP00000006120	ENSSGRP00000101525	ENSSGRP00000006120	ENSSGRP00000101525	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein deacetylase sirtuin-6-like.	0.662
ENSSGRP00000006120	LOC107553976	ENSSGRP00000006120	ENSSGRP00000064449	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein deacetylase sirtuin-3-like.	0.684
ENSSGRP00000006120	LOC107561440	ENSSGRP00000006120	ENSSGRP00000032423	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein deacetylase sirtuin-3-like isoform X1.	0.541
ENSSGRP00000006120	LOC107568197	ENSSGRP00000006120	ENSSGRP00000061050	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial-like.	0.586
ENSSGRP00000006120	sirt2	ENSSGRP00000006120	ENSSGRP00000080800	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	NAD-dependent protein deacetylase sirtuin-2 isoform X1.	0.736
ENSSGRP00000013288	ENSSGRP00000006120	ENSSGRP00000013288	ENSSGRP00000006120	Sirtuin 7.	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	0.628
ENSSGRP00000013288	ENSSGRP00000104985	ENSSGRP00000013288	ENSSGRP00000104985	Sirtuin 7.	annotation not available	0.640
ENSSGRP00000013288	ENSSGRP00000112702	ENSSGRP00000013288	ENSSGRP00000112702	Sirtuin 7.	annotation not available	0.560
ENSSGRP00000013288	LOC107562394	ENSSGRP00000013288	ENSSGRP00000017436	Sirtuin 7.	NAD-dependent protein deacetylase sirtuin-1-like.	0.669
ENSSGRP00000013288	LOC107565065	ENSSGRP00000013288	ENSSGRP00000104983	Sirtuin 7.	NAD-dependent protein deacetylase sirtuin-1-like isoform X1.	0.670
ENSSGRP00000013288	LOC107568197	ENSSGRP00000013288	ENSSGRP00000061050	Sirtuin 7.	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial-like.	0.732
ENSSGRP00000013288	LOC107581456	ENSSGRP00000013288	ENSSGRP00000109872	Sirtuin 7.	NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1.	0.555
ENSSGRP00000013288	sirt2	ENSSGRP00000013288	ENSSGRP00000080800	Sirtuin 7.	NAD-dependent protein deacetylase sirtuin-2 isoform X1.	0.454
ENSSGRP00000013593	ENSSGRP00000006120	ENSSGRP00000013593	ENSSGRP00000006120	NAD-dependent protein deacetylase sirtuin-3-like.	NAD-dependent protein deacylase sirtuin-5, mitochondrial-like.	0.541