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Tint_0777 Tint_0777 sucC sucC sucD sucD Tint_1393 Tint_1393 Tint_2337 Tint_2337 Tint_2338 Tint_2338 Tint_2339 Tint_2339 Tint_2340 Tint_2340 prpB prpB Tint_2344 Tint_2344 Tint_2346 Tint_2346 Tint_2347 Tint_2347 Tint_2512 Tint_2512
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tint_0777KEGG: lch:Lcho_2003 succinic semialdehyde dehydrogenase; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (401 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
Tint_1393TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: cti:RALTA_A2531 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (416 aa)
Tint_2337KEGG: bbr:BB3679 succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
Tint_2338KEGG: bur:Bcep18194_B2150 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (587 aa)
Tint_2339KEGG: bte:BTH_II0661 succinate dehydrogenase, hydrophobic membrane anchor protein; TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: succinate dehydrogenase cytochrome b subunit. (121 aa)
Tint_2340KEGG: mpt:Mpe_A2170 succinate dehydrogenase subunit C; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit. (137 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (296 aa)
Tint_2344TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: reu:Reut_A2329 methylcitrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family. (387 aa)
Tint_23462-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; manually curated; KEGG: bpt:Bpet1812 2-methylcitrate dehydratase; TIGRFAM: 2-methylcitrate dehydratase. (483 aa)
Tint_2347Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (911 aa)
Tint_2512KEGG: vap:Vapar_4079 isocitrate dehydrogenase (NAD(+)); PFAM: isocitrate/isopropylmalate dehydrogenase. (343 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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